Peptidase specificity

Specificity is only shown where there are at least ten known substrates for a peptidase. The brighter the shade of green the greater the preference at each position. Positions where no amino acid is possible (for example P4-P2 for an aminopeptidase or P2'-P4' for a carboxypeptidase) are shown with a grey background.

MEROPS ID	Peptidase name	Total cleavages	P4	P3	P2	P1	P1'	P2'	P3'	P4'
A01.001	pepsin A	970
A01.002	pepsin B	25	P			F		R	L
A01.003	gastricsin	50
A01.004	BACE1 g.p. (Homo sapiens)	25
A01.006	chymosin	20				F
A01.007	renin	10	P	F	H	L	L	V	HY	S
A01.008	renin-2	3
A01.009	cathepsin D	924
A01.010	cathepsin E	1596
A01.011	penicillopepsin	17			A	K		A
A01.012	rhizopuspepsin	249
A01.013	mucorpepsin	9
A01.014	candidapepsin SAP1	26	L	V	E			Y	L	V
A01.015	barrierpepsin	1
A01.016	aspergillopepsin I	157
A01.017	endothiapepsin	11
A01.018	saccharopepsin	14
A01.019	polyporopepsin	11
A01.020	phytepsin	62
A01.021	plasmepsin (Plasmodium sp.)	5
A01.022	plasmepsin-1	13				F
A01.023	plasmepsin-2	15				F
A01.027	trichodermapepsin	1
A01.030	yapsin-1	46
A01.031	yapsin-2	16		Y		R	E	A	E	A
A01.035	yapsin-3	9
A01.036	axp peptidase (Yarrowia lipolytica)	3
A01.037	canditropsin	9
A01.038	candiparapsin	5
A01.040	nepenthesin	733
A01.041	BACE2 g.p. (Homo sapiens)	33
A01.042	syncephapepsin	18
A01.043	histoaspartic peptidase (Plasmodium falciparum)	4
A01.045	nothepsin	1
A01.046	napsin A	7
A01.051	pepsin F	3
A01.053	necepsin-1	133
A01.054	tick heme-binding aspartic proteinase (Rhipicephalus microplus)	2
A01.055	Mername-AA047 peptidase	1
A01.056	Yps1 protein (Schizosaccharomyces pombe)	3
A01.059	plasmepsin-4	8
A01.060	candidapepsin SAP2	22	L	V	E	L		Y	L	V
A01.061	candidapepsin SAP3	21	L	V	E	L		Y	L	V
A01.064	candidapepsin SAP6	22	L	V	E	L	L	Y	L	V
A01.067	candidapepsin SAP9	17
A01.068	necepsin-2	45
A01.069	CDR1 peptidase (Arabidopsis-type)	2
A01.070	pepsin A4	4
A01.071	pepsin A5 (Homo sapiens)	10
A01.073	nucellin	1
A01.075	plasmepsin-5 (Plasmodium sp.)	7
A01.076	Sapp2p peptidase (Candida parapsilosis)	7
A01.084	yolk cathepsin (Boophilus sp.)	17				L
A01.085	candidapepsin SAP10	16				K
A01.088	pepsin (fish)	2
A01.089	pregnancy-associated glycoprotein 2	1
A01.093	CAD3 peptidase (Musca domestica)	2
A01.094	pregnancy-associated glycoprotein 12	1
A01.095	shewasin A (Shewanella amazonensis)	5
A01.096	chlapsin	1
A01.097	GPI-anchored aspartic peptidase (Saccharomyces-type)	1
A01.098	ASP5 g.p. (Toxoplasma gondii)	1
A01.UPA	subfamily A1A unassigned peptidases	1
A02.001	HIV-1 retropepsin	1046
A02.002	HIV-2 retropepsin	30	S		N			I	V	Q
A02.004	equine infectious anaemia virus retropepsin	13	S	Q	N	Y	P	I	V	Q
A02.005	bovine immunodeficiency virus retropepsin	11
A02.007	feline immunodeficiency virus retropepsin	28			V
A02.008	murine leukemia virus-type retropepsin	20	S		N	Y	P	I	V	Q
A02.009	Mason-Pfizer leukemia virus retropepsin	18	S	Q	N	Y	P	I	V	Q
A02.010	mouse mammary tumor virus retropepsin	13	S		N		P	I	V	Q
A02.011	human endogenous retrovirus K retropepsin	100
A02.012	retropepsin (human T-cell leukemia virus)	15			IV	L	P	V
A02.013	bovine leukemia virus retropepsin	20	S		N		P	I	V	Q
A02.015	Rous sarcoma virus retropepsin	18	S		N	Y	P	I	V	Q
A02.016	intracisternal A-particle retropepsin	7
A02.020	porcine endogenous retrovirus peptidase	6
A02.022	Ty3 transposon peptidase	5
A02.024	rabbit endogenous retrovirus endopeptidase	1
A02.061	Ulysses retrotransposon retropepsin	6
A02.063	walleye dermal sarcoma virus retropepsin	25			NQ		P	I
A03.001	cauliflower mosaic virus-type peptidase	1
A03.002	bacilliform virus peptidase	6
A05.001	thermopsin	18
A08.001	signal peptidase II	5
A09.001	spumapepsin	11			V	N		V	T
A11.001	Copia transposon peptidase	9
A11.003	Ty1 transposon peptidase	3
A22.001	presenilin 1	19
A22.003	impas 1 peptidase	6
A22.004	signal peptide peptidase-like protein 2B	5
A22.007	signal peptide peptidase-like protein 2A	5
A22.015	intramembrane aspartyl peptidase (Methanoculleus marisnigri JR1)	8
A24.001	type 4 prepilin peptidase 1	16		Q		G	F	T	L	I
A24.016	FlaK peptidase	6
A24.017	PibD peptidase	18		K	K	G	A	ST	GS	IT
A24.018	EppA peptidase	2
A25.001	gpr peptidase	32	M	K		E	I	A	S	E
A26.001	omptin	54				R	R
A26.002	OmpP peptidase	11	L	A	A	R	R	G	A	G
A26.003	plasminogen activator Pla	16				R	R	I
A26.004	protein E (Salmonella sp.)	2
A26.005	IcsP peptidase (Shigella flexneri)	1
A28.004	skin SASPase	15	S	F	L	Y	Q	V	S	T
A31.001	HybD peptidase	4
A31.003	HycI peptidase	1
A31.005	hupW peptidase	1
A31.006	FrxA peptidase	1
A32.002	RC1339 g.p. (Rickettsia conorii)	800
A36.001	sporulation factor SpoIIGA	4
A37.001	sso1175 g.p. (Sulfolobus solfataricus)	6
A39.001	TseI g.p. (Aeromonas dhakensis)	4
A9G.010	pycnoporopepsin	8
A9G.017	acid peptidase (Cladosporium)	8
A9G.019	acrocylindropepsin	6
A9G.020	yapsin A	9
C01.001	papain	89					Q			D
C01.002	chymopapain	12
C01.003	caricain	9
C01.004	glycyl endopeptidase	3
C01.005	stem bromelain	26
C01.006	ficin	17
C01.007	actinidin	19
C01.008	asclepain A	11
C01.009	cathepsin V	5799
C01.010	vignain	80					Q	Q
C01.011	calotropain	1
C01.013	cathepsin X	46						0-	0-	0-
C01.017	zingipain	1
C01.018	cathepsin F	3406
C01.019	CC-I peptidase (Vasconcellea sp.)	1
C01.020	CC-III peptidase (Vasconcellea-type)	3
C01.024	endopeptidase-B (Hordeum-type)	70					Q	P
C01.026	ananain	17						0-	0-	0-
C01.027	comosain	13	0-					0-	0-	0-
C01.028	fruit bromelain	4
C01.029	pseudotzain	1
C01.030	crustapain	10
C01.032	cathepsin L	6703
C01.033	cathepsin L1 (Fasciola sp.)	196
C01.034	cathepsin S	3126
C01.035	cathepsin O	2
C01.036	cathepsin K	10608
C01.037	cathepsin W	4
C01.038	cathepsin P	10		K	L	R	S	S	K	Q
C01.040	cathepsin H	48
C01.041	aleurain	6
C01.044	SmCL2 peptidase	4
C01.046	falcipain-2	152
C01.049	cathepsin B, plant form	1
C01.050	histolysain	11			R	R
C01.057	vinckepain-2	28			L
C01.060	cathepsin B	4712
C01.061	SmCB2 peptidase (Schistosoma-type)	2
C01.062	cathepsin B-like peptidase (platyhelminth)	55
C01.063	falcipain-3	126
C01.064	RD21 peptidase	20				R
C01.066	CPL-1 peptidase (Caenorhabditis elegans-type)	4
C01.067	insect 26/29 kDa peptidase	6
C01.068	vitellogenic cathepsin B	1
C01.070	dipeptidyl-peptidase I	33
C01.071	toxopain-1	3
C01.072	rhodesain	11
C01.073	peptidase 1 (mite)	29
C01.074	CPB peptidase	17		K	L	R	F	S	K	Q
C01.075	cruzipain	65			L
C01.076	CPA peptidase	2
C01.077	falcipain-1	2
C01.079	papain homologue (Theileria-type)	5
C01.081	papain homologue (Dictyostelium-type)	2
C01.082	Mername-AA287 peptidase	3
C01.083	V-cath peptidase	1
C01.084	bleomycin hydrolase (animal)	19
C01.085	bleomycin hydrolase (yeast)	9
C01.086	aminopeptidase C	22	0-	0-	0-					0-
C01.088	oligopeptidase E	8
C01.089	peptidase G	4
C01.092	cathepsin L1 (arthropod-type)	12
C01.093	miltpain	1
C01.094	giardain	2
C01.096	melain G	6
C01.097	phytolacain	13
C01.098	CPC peptidase	9
C01.099	ervatamin B	6
C01.100	cruzipain 2	26		K	L	R	F	S	K	Q
C01.101	cathepsin B-like peptidase, nematode	47
C01.113	tetrain	1
C01.115	fascipain B	10				R
C01.116	ervatamin C	7
C01.120	Mername-AA249 peptidase	2
C01.124	dipeptidylpeptidase I (Plasmodium-type)	6
C01.125	Cwp84 peptidase	2
C01.127	TsCL-1 peptidase	2
C01.128	xylellain	2
C01.129	cathepsin L3 (Fasciola sp.)	72
C01.130	CSCP3 peptidase (Clonorchis-type)	56
C01.133	CmCatB (Callosobruchus maculatus)-type peptidase	1
C01.137	ervatamin A	8
C01.141	GsCL1 peptidase (Gnathostoma spinigerum)	1
C01.142	cathepsin L2 (Fasciola sp.)	54
C01.143	intestain D4 (Leptinotarsa decemlineata)	1
C01.144	cathepsin B-like cysteine peptidase (Raphanus sativus)	24
C01.145	hieronymain I	1
C01.146	hieronymain II	1
C01.147	hieronymain III	1
C01.149	TgCPL peptidase (Toxoplasma-type)	7
C01.150	asclepain f (Asclepias fruticosa)	5
C01.152	SmCL3 peptidase (Schistosoma-type)	1
C01.153	araujiain (Araujia sp.)	5
C01.155	EhCP4 peptidase (Entamoeba histolytica)	2
C01.157	vivapain-4 (Plasmodium vivax)	4
C01.158	asclepain cI (Asclepias curassavica)	1
C01.159	asclepain cII (Asclepias curassavica)	6
C01.160	morrenain b I (Morrenia brachystephana)	3
C01.161	morrenain b II (Morrenia brachystephana)	1
C01.164	CPXaC peptidase (Xanthomonas sp.)	1
C01.165	TgCPC1 (Toxoplasma gondii)	2
C01.166	SmCL1 peptidase (Schistosoma mansoni and similar)	9
C01.167	Cwp13 (Clostridium difficile)	1
C01.168	endopeptidase-A (Hordeum-type)	20	0-		L		Q	P		D
C01.169	SERA6 (Plasmodium sp.)	1
C01.170	macrodontain	8
C01.171	Pd_dinase (Parabacteroides distasonis)	4
C01.172	endopeptidase (bacterium symbiont of Theonella swinhoei)	2
C01.984	serine-repeat antigen (Plasmodium sp.)	2
C01.UPA	subfamily C1A unassigned peptidases	3
C02.001	calpain-1	431
C02.002	calpain-2	453
C02.004	calpain-3	19
C02.007	calpain-8	2
C02.009	calpain tra-3	1
C02.014	calpain A	3
C02.015	calpain B	4
C02.018	calpain-10	1
C02.022	Tpr peptidase (Porphyromonas gingivalis)	1
C02.028	calpain-7	1
C02.029	calpain (Plasmodium-type)	1
C03.001	poliovirus-type picornain 3C	14	A			Q	G
C03.003	cowpea mosaic comovirus-type picornain 3C	6
C03.004	grapevine fanleaf-type nepovirus picornain 3C	3
C03.005	hepatitis A virus-type picornain 3C	9
C03.007	human rhinovirus 2-type picornain 3C	6
C03.008	foot-and-mouth disease virus picornain 3C	5
C03.009	cardiovirus picornain 3C	9
C03.011	Coxsackievirus-type picornain 3C	10	A	L	F	Q	G	P	P	V
C03.012	tomato ringspot nepovirus picornain 3C	7
C03.013	human rhinovirus 14-type 3C peptidase	3
C03.014	human enterovirus 71 3C peptidase	10	A			Q	G
C03.015	Plautia stali intestine virus picornain C3	4
C03.016	tomato marchitez virus 3C peptidase	6
C03.020	enterovirus picornain 2A	12	L		T		G
C03.021	rhinovirus picornain 2A	12					G
C03.024	rice tungro spherical virus-type peptidase	2
C03.025	tomato black ring virus-type picornain	5
C04.001	nuclear-inclusion-a peptidase (plum pox virus)	21	V		H	Q
C04.003	tobacco vein mottling virus-type NIa peptidase	13	V	R	F	Q	S	G	T	R
C04.004	tobacco etch virus NIa peptidase	14	V	RY	F	Q	S	G	T	R
C04.008	bean yellow mosaic virus-type NIa peptidase	7
C04.014	potato virus A NIa peptidase	7
C05.001	adenain	26			G	G
C06.001	potato virus Y-type helper component peptidase	2
C07.001	chestnut blight fungus virus p29 peptidase	1
C08.001	chestnut blight fungus virus p48 peptidase	1
C09.001	sindbis virus-type nsP2 peptidase	6
C10.001	streptopain	28
C10.002	PrtT peptidase	1
C10.003	periodontain	2
C10.004	interpain A	22
C101.001	OTULIN peptidase	1
C102.001	GtgE peptidase	1
C104.002	PlyPy phage lysin	1
C105.001	papain-like peptidase 1 alpha (simian hemorrhagic fever virus)	2
C106.001	archaeosortase A (Haloferax volcanii )	2
C107.001	alphamesonivirus 3C-like peptidase	2
C108.001	Prp peptidase (Staphylococcus aureus)	1
C108.002	bacteriophage Cp-1 orf13 protein	1
C11.001	clostripain	9
C11.003	PmC11 peptidase (Parabacteroides merdae)	7
C11.004	fragipain (Bacteroides fragilis)	2
C11.005	thetapain	1
C11.006	clostripain-related protein (Bacteroides thetaiotaomicron)	3
C110.001	kyphoscoliosis peptidase	1
C111.001	coagulation factor XIIIa	1
C113.001	IgdE peptidase (Streptococcus suis)	8
C115.001	MINDY-1 protein	1
C118.001	EspL g.p. (Escherichia coli)	2
C12.001	ubiquitinyl hydrolase-L1	8
C12.002	ubiquitinyl hydrolase-YUH1	6
C12.003	ubiquitinyl hydrolase-L3	26	L	R	G	G
C12.004	ubiquitinyl hydrolase-BAP1	1
C12.005	ubiquitinyl hydrolase-L5	1
C12.008	ubiquitinyl hydrolase UCH-D	3
C120.001	mavirus processing peptidase	4
C121.001	MINDY-4 peptidase	1
C124.001	Lem27 (Legionella pneumophila)	5
C13.001	legumain (plant beta form)	15				N
C13.002	legumain (plant alpha form)	9
C13.004	legumain, animal-type	2266				N
C13.005	glycosylphosphatidylinositol:protein transamidase	19						A
C13.006	legumain (plant gamma form)	1
C13.007	legumain, trematode-type	6
C13.008	legumain, Blastocystis-type	1
C13.009	butelase 1	12	C	Y		N	H	V	I	A
C13.A01	legumain (plant delta form)	1
C14.001	caspase-1	189				D
C14.002	CED-3 peptidase	14	D			D	G
C14.003	caspase-3	701				D
C14.004	caspase-7	502				D
C14.005	caspase-6	1307				D
C14.006	caspase-2	290				D	G
C14.007	caspase-4	11		E		D
C14.008	caspase-5	4
C14.009	caspase-8	72				D
C14.010	caspase-9	14				D
C14.011	caspase-10	10				D
C14.012	caspase-11	9
C14.013	caspase-12	5
C14.015	caspase (insect 1)	8
C14.016	caspase (insect 2)	3
C14.018	caspase-14	17				D
C14.019	caspase DRONC (Drosophila melanogaster)	11		E		D
C14.022	caspase DECAY	8
C14.024	Mername-AA065 peptidase	1
C14.025	caspase DAMM (Drosophila sp.)	4
C14.026	paracaspase	30	L		S	R	G
C14.030	Caspy peptidase (Brachydanio rerio-type)	2
C14.031	Caspy2 g.p. (Brachydanio rerio)	1
C14.033	metacaspase-4 (Arabidopsis-type)	7
C14.034	metacaspase-9 (Arabidopsis-type)	5
C14.035	metacaspase Yca1 (Saccharomyces cerevisiae-type)	11				R		0-	0-	0-
C14.036	metacaspase mcII-Pa (Picea abies)-like peptidase	3
C14.037	SfAV caspase (Spodoptera frugiperda ascovirus)	1
C14.038	caspase-15	5
C14.040	caspase Dredd	4
C14.043	metacaspase Ld (Leishmania-type)	27				R
C14.044	metacaspase TbMCA2	11				R			A
C14.046	metacaspase Atmc8 (Arabidopsis thaliana)	2
C14.047	metacaspase-1 (Arabidopsis-type)	9
C14.049	metacaspase Atmc5 (Arabidopsis sp.)	9
C14.050	orthocaspase MaOC1 (Microcystis aeruginosa)	9
C14.A06	csp-1 g.p. (Caenorhabditis elegans)	7
C15.001	pyroglutamyl-peptidase I (prokaryote)	3
C15.010	pyroglutamyl-peptidase I (chordate)	6
C15.012	pyroglutamyl-peptidase I (Trypanosoma-type)	4
C16.001	murine hepatitis coronavirus papain-like peptidase 1	4
C16.002	human coronavirus 229E papain-like peptidase 1	3
C16.005	avian infectious bronchitis coronavirus papain-like peptidase	2
C16.006	mouse hepatitis coronavirus papain-like peptidase 2	2
C16.009	severe acute respiratory syndrome coronavirus papain-like peptidase	3
C16.010	human coronavirus 229E papain-like peptidase 2	3
C16.012	coronavirus COVID-19 papain-like peptidase	8
C18.001	hepatitis C virus peptidase 2	1
C18.UPW	family C18 unassigned peptidases	1
C19.001	ubiquitin-specific peptidase 5	10	L	R	G	G
C19.002	Ubp1 ubiquitin peptidase	3
C19.003	Ubp2 ubiquitin peptidase	3
C19.004	Ubp3 ubiquitin peptidase	2
C19.005	Doa4 ubiquitin peptidase	2
C19.010	ubiquitin-specific peptidase 4	12	L	R	G	G
C19.011	ubiquitin-specific peptidase 8	6
C19.012	ubiquitin-specific peptidase 13	3
C19.013	ubiquitin-specific peptidase 2	9
C19.014	ubiquitin-specific peptidase 11	1
C19.016	ubiquitin-specific peptidase 7	12	L	R	G	G	K
C19.017	ubiquitin-specific peptidase 9X	6
C19.018	ubiquitin-specific peptidase 10	3
C19.019	ubiquitin-specific peptidase 1	2
C19.022	ubiquitin-specific peptidase 15	10	L	R	G	G	M
C19.023	ubiquitin-specific peptidase 17	1
C19.024	ubiquitin-specific peptidase 19	1
C19.025	ubiquitin-specific peptidase 20	2
C19.028	ubiquitin-specific peptidase 9Y	2
C19.030	ubiquitin-specific peptidase 18	2
C19.034	ubiquitin-specific peptidase 21	2
C19.037	ubiquitin-specific peptidase 33	4
C19.042	ubiquitin-specific peptidase 36	1
C19.046	ubiquitin-specific peptidase 26 (Homo sapiens-type)	1
C19.047	ubiquitin-specific peptidase 24	1
C19.048	ubiquitin-specific peptidase 42	1
C19.052	ubiquitin-specific peptidase 46	1
C19.053	ubiquitin-specific peptidase 37	2
C19.054	ubiquitin-specific peptidase 28	1
C19.056	ubiquitin-specific peptidase 38	1
C19.057	ubiquitin-specific peptidase 44	4
C19.059	ubiquitin-specific peptidase 35	1
C19.060	ubiquitin-specific peptidase 30	3
C19.064	ubiquitin-specific peptidase 45	1
C19.065	ubiquitin-specific peptidase 51	1
C19.067	ubiquitin-specific peptidase 34	3
C19.073	ubiquitin-specific peptidase 49	1
C19.078	USP17-like peptidase	2
C19.079	ubiquitin-specific peptidase 6 (Saccharomyces-type)	4
C19.087	ubiquitin-specific peptidase 8 (Saccharomyces cerevisiae)	1
C19.088	ubiquitin-specific peptidase 10 (Saccharomycetales)	1
C19.094	UBP6 peptidase (Arabidopsis-type)	1
C19.099	UBP15 peptidase (Saccharomyces cerevisiae)	8
C19.100	ubiquitin carboxyl-terminal hydrolase 13 (Saccharomyces cerevisiae)	1
C19.101	ubiquitin carboxy-terminal hydrolase 7 (Saccharomyces cerevisiae)	1
C19.102	putative ubiquitin carboxyl-terminal hydrolase ybl067c (Saccharomyces cerevisiae)	1
C19.103	putative ubiquitin carboxyl-terminal hydrolase ybr058c (Saccharomyces cerevisiae)	4
C19.104	ubpA (Dictyostelium discoideum)	1
C21.001	tymovirus peptidase	3
C23.001	carlavirus peptidase	1
C24.002	feline calicivirus 3C-like peptidase	8
C24.003	sapovirus 3C-like peptidase	10	F		E	EQ	G		T	D
C25.001	gingipain RgpA	26				R
C25.002	gingipain K	47				K
C25.003	gingipain RgpB	16				R
C26.001	gamma-glutamyl hydrolase	3
C27.001	rubella virus peptidase	1
C28.001	foot-and-mouth disease virus L-peptidase	7
C28.002	equine rhinovirus L-peptidase	2
C30.001	coronavirus picornain 3C-like peptidase-1	44			L	Q	S
C30.002	avian infectious bronchitis coronavirus 3C-like peptidase	18			L	Q	S
C30.003	human coronavirus 229E main peptidase	14			L	Q
C30.004	porcine transmissible gastroenteritis virus-type main peptidase	4
C30.005	SARS coronavirus picornain 3C-like peptidase	27				GQ
C30.007	coronavirus COVID-19 3C-like peptidase	28			L	Q
C30.UPW	family C30 unassigned peptidases	3
C32.001	equine arteritis virus-type cysteine peptidase	5
C32.002	papain-like peptidase 1 beta (simian hemorrhagic fever virus)	1
C32.003	papain-like peptidase 1 gamma (simian hemorrhagic fever virus)	1
C33.001	equine arteritis virus Nsp2-type cysteine peptidase	5
C37.001	calicivirin	11			L	Q	G	P	E
C37.003	murine norovirus NS6 peptidase	1
C39.001	bacteriocin-processing peptidase	13	I		G	G
C39.003	streptococcin processing peptidase	1
C39.004	mersacidin lantibiotic processing peptidase	1
C39.005	colicin V processing peptidase	1
C39.007	lacticin 481 processing peptidase (Lactococcus lactis)	16	I	L	G	A	K	G	G	S
C40.001	dipeptidyl-peptidase VI (bacteria)	1
C40.004	spr peptidase	2
C40.005	PgdS peptidase	1
C40.007	YddH peptidase	1
C40.009	NLP/P60 (Nostoc punctiforme)-like putative peptidase	1
C40.010	CwlO peptidase (Bacillus sp.)	1
C40.011	RipA peptidoglycan hydrolase	4
C40.012	RipB peptidoglycan hydrolase	3
C40.013	YdhO protein (Escherichia coli)	1
C40.014	BacL1 peptidase (Enterococcus faecalis)	1
C42.001	beet yellows virus-type papain-like peptidase	1
C42.003	L1 peptidase (Citrus tristeza virus)	1
C42.004	L2 peptidase (grapevine leafroll-associated virus 2)	1
C44.001	amidophosphoribosyltransferase precursor	1
C45.001	acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase precursor	2
C46.001	hedgehog protein	2
C46.002	Sonic hedgehog protein	4
C46.003	Indian hedgehog protein	2
C46.004	Desert hedgehog protein	2
C46.005	Tiggy-winkle protein	1
C47.001	staphopain A	6
C47.002	staphopain B	9
C47.003	EcpA peptidase	8
C47.004	staphopain C	10
C48.001	Ulp1 peptidase	2
C48.002	SENP1 peptidase	32	Q	T	G	G	K
C48.003	SENP3 peptidase	8
C48.004	SENP6 peptidase	13	Q	T	G	G	K
C48.007	SENP2 peptidase	20	Q	T	G	G	K
C48.008	SENP5 peptidase	13	Q	T	G	G	K
C48.009	SENP7 peptidase	2
C48.011	SENP8 peptidase	8
C48.023	XopD peptidase	3
C48.031	SENP8 peptidase (fungus-type)	2
C48.032	ChlaDub1 peptidase	2
C48.034	PfSENP1 (Plasmodium falciparum)	2
C48.A03	At5g60190 (Arabidopsis thaliana)	1
C48.A04	At1g60220 (Arabidopsis thaliana)	1
C48.A05	At1g10570 (Arabidopsis thaliana)	1
C49.001	Strawberry mottle virus 3C-like peptidase	5
C50.001	separase (yeast-type)	12	E		G	R
C50.002	separase (Homo sapiens-type)	7
C50.003	separase (Drosophila-type)	1
C51.001	D-alanyl-glycyl peptidase (staphylococcal phage phi11-type)	1
C51.002	bacteriophage B30 lysin	3
C53.001	pestivirus Npro peptidase	4
C54.001	ATG4 peptidase	4
C54.002	autophagin-2	6
C54.003	autophagin-1	15		T	F	G
C54.004	autophagin-3	3
C54.005	autophagin-4	2
C54.007	ATG4.2 peptidase (Leishmania-type)	2
C54.008	atg-4.1 peptidase (Caenorhabditis elegans-type)	1
C54.009	atg-4.2 peptidase (Caenorhabditis elegans-type)	1
C54.010	autophagin-2 (Trypanosoma cruzi)	2
C55.001	YopJ protein	4
C56.001	PfpI peptidase	1
C56.002	DJ-1 putative peptidase	1
C56.006	Hsp31 peptidase	7
C57.001	vaccinia virus I7L processing peptidase	4
C58.001	YopT peptidase	3
C58.002	AvrPphB peptidase	2
C58.004	NopT g.p. (Rhizobium sp. NGR234)	1
C58.005	RipT g.p. (Ralstonia solanacearum GMI1000)	1
C58.007	ORF4 g.p. (Pseudomonas syringae)	1
C59.001	penicillin V acylase precursor	1
C60.001	sortase A (Staphylococcus-type)	21	L	P		T	G
C60.002	sortase B	5
C60.003	sortase C2	1
C60.004	sortase C (Bacillus-type)	2
C60.006	sortase A (Streptococcus-type)	9
C60.007	sortase C1 (Streptococcus sp.)	1
C62.001	gill-associated virus 3C-like peptidase	2
C63.001	African swine fever virus processing peptidase	7
C64.001	Cezanne peptidase	5
C64.002	Cezanne-2 peptidase	1
C64.003	A20 peptidase	3
C64.004	trabid peptidase	8
C64.006	VCIP135 deubiquitinating peptidase	2
C65.001	otubain-1	14	L	R	G	G	K
C65.002	otubain-2	2
C66.001	IdeS peptidase	2
C66.002	dentipain	2
C67.001	CylD peptidase	7
C69.001	dipeptidase A	2
C69.002	arginine aminopeptidase (Streptococcus-type)	11	0-	0-	0-	R
C70.001	AvrRpt2 peptidase	3
C71.001	pseudomurein endoisopeptidase Pei	1
C74.001	pestivirus NS2 peptidase	1
C75.001	AgrB peptidase	1
C76.001	viral tegument protein deubiquitinylating peptidase	4
C78.001	UfSP1 peptidase	3
C78.002	UfSP2 peptidase	2
C78.003	ZUP1 g.p. (Homo sapiens)	3
C78.004	Mug105 (Saccharomyces pombe)	3
C79.001	ElaD peptidase (Escherichia-type)	3
C80.001	RTX self-cleaving toxin	5
C80.002	self-cleaving toxin A (Clostridium-type)	1
C80.003	self-cleaving toxin B (Clostridium-type)	1
C82.001	L,D-transpeptidase (Enterococcus-type)	1
C82.002	Ldt(fs) transpeptidase	2
C82.A01	LdtF protein (Escherichia coli)	1
C83.001	gamma-glutamylcysteine dipeptidyltranspeptidase	1
C83.002	phytochelatin synthase	1
C84.001	prtH peptidase (Tannerella forsythensis ATCC 43037)	1
C85.001	OTUD5 peptidase (Homo sapiens)	4
C85.003	OTUD3 peptidase (Homo sapiens)	2
C85.004	OTUD1 peptidase (Homo sapiens)	1
C85.006	OTU1 peptidase (Saccharomyces cerevisiae-type)	3
C85.007	YOD1 peptidase	4
C85.008	OTU2 peptidase (Saccharomyces cerevisiae-type)	5
C86.001	ataxin-3	1
C86.003	ataxin-3 homologue (Caenorhabditis sp.)	1
C87.001	nairovirus deubiquitinylating peptidase	3
C89.001	acid ceramidase precursor	1
C89.002	N-acylethanolamine acid amidase precursor	1
C93.001	LapG peptidase (Pseudomonas fluorescens)	1
C95.001	lysosomal 66.3 kDa protein (Mus musculus-type)	2
C96.001	McjB peptidase	1
C97.001	desumoylating isopeptidase 1	1
C98.001	USPL1 peptidase	4
C99.001	iflavirus processing peptidase	2
C9B.001	lysosomal dipeptidase II	1
C9C.001	dipeptidyl-dipeptidase	4
C9G.001	cathepsin N	14
C9G.030	bothropain	12			F	R				0-
C9G.031	protease-B-17N-1 (Bacillus sp. 17N-1)	2
G01.001	scytalidoglutamic peptidase	37		K	L			S	K	Q
G01.002	aspergilloglutamic peptidase	68
G01.005	PMAP-1 peptidase (Penicillium marneffei)	3
G02.001	pre-neck appendage protein (Bacillus phage phi29)	1
G03.001	strawberry mottle virus glutamic peptidase	3
G04.001	Tiki1 peptidase	1
G05.001	RCE1 peptidase (Saccharomyces cerevisiae-type)	4
G05.002	RCE1 peptidase (Homo sapiens-type)	22	K	T	K		V	I		0-
G05.004	microcystinase MlrA	1
G05.005	RCE1 peptidase (Sarcomastigophora-type)	1
G06.001	Ras/Rap1-specific peptidase	2
M01.001	aminopeptidase N	42	0-	0-	0-
M01.002	lysyl aminopeptidase (bacteria)	22	0-	0-	0-
M01.003	aminopeptidase A	14	0-	0-	0-	E
M01.004	leukotriene A4 hydrolase	21	0-	0-	0-
M01.005	alanyl aminopeptidase (bacterial-type)	66						0-	0-	0-
M01.006	Ape2 aminopeptidase	4
M01.007	Aap1' aminopeptidase	1
M01.008	pyroglutamyl-peptidase II	3
M01.009	aminopeptidase N (actinomycete-type)	11	0-	0-	0-			0-	0-	0-
M01.010	cytosol alanyl aminopeptidase	57
M01.011	cystinyl aminopeptidase	11	0-	0-	0-
M01.013	aminopeptidase N (insect)	29	0-	0-	0-			0-	0-	0-
M01.014	aminopeptidase B	16	0-	0-	0-	R
M01.015	aminopeptidase H11 (nematode)	3
M01.016	aminopeptidase Ey	18	0-	0-
M01.018	endoplasmic reticulum aminopeptidase 1	80	0-	0-	0-	T	V
M01.020	tricorn interacting factor F2	6
M01.021	tricorn interacting factor F3	3
M01.022	arginyl aminopeptidase-like 1	14	0-	0-	0-			0-	0-	0-
M01.024	ERAP2 aminopeptidase	27	0-	0-	0-
M01.025	aminopeptidase-1 (Caenorhabditis-type)	7
M01.026	aminopeptidase Q	17	0-	0-
M01.028	aminopeptidase O	3
M01.029	M1 aminopeptidase (Plasmodium spp.)	7
M01.030	aminopeptidase N2 (insect)	4
M01.031	cold-active aminopeptidase (Colwellia psychrerythraea)-type peptidase	2
M01.032	lysyl aminopeptidase 1 (Streptomyces sp.)	8
M01.033	lysyl endopeptidase (Streptomyces albulus)	1
M01.034	leukotriene A4 hydrolase (Saccharomyces cerevisiae)	6
M01.035	LePepA g.p. (Legionella pneumophila)	2
M01.036	ApiP peptidase (Actinoplanes sp. NAI112)	16
M01.UPW	family M1 unassigned peptidases	9
M02.001	angiotensin-converting enzyme peptidase unit 1	8
M02.002	peptidyl-dipeptidase Acer	11
M02.003	peptidyl-dipeptidase Ance	7
M02.004	angiotensin-converting enzyme peptidase unit 2	13
M02.005	peptidyl-dipeptidase A (Theromyzon-type)	4
M02.006	angiotensin-converting enzyme-2	14				P		0-	0-	0-
M02.007	peptidyl-dipeptidase A (Crassostrea-type)	3
M03.001	thimet oligopeptidase	124	G						Q
M03.002	neurolysin	128	G			P			Q
M03.003	saccharolysin	8
M03.004	oligopeptidase A	10			P
M03.005	peptidyl-dipeptidase Dcp	8
M03.006	mitochondrial intermediate peptidase	34
M03.007	oligopeptidase F	24
M03.009	oligopeptidase MepB	1
M03.010	Pz-peptidase A	13			P	L	G	P
M03.011	tropolysin	34	G	F	S	P	F	R	Q
M03.A12	OCT1 (Arabidopsis thaliana)	12
M04.001	thermolysin	3994
M04.003	vibriolysin	17
M04.005	pseudolysin	70					L
M04.006	Msp peptidase (Legionella-type)	8
M04.007	coccolysin	25
M04.008	Mpl peptidase (Listeria sp.)	1
M04.009	aureolysin	24
M04.010	vimelysin	12					FL
M04.011	lambda toxin	4
M04.014	bacillolysin	41				G	L
M04.016	PA peptidase (Aeromonas-type)	2
M04.017	griselysin	36				G	L	A
M04.018	stearolysin	5
M04.019	MprIII (Alteromonas sp. strain O-7)	1
M04.021	neutral peptidase (Thermoactinomyces-type)	1
M04.024	PrtS peptidase (Photorhabdus luminescens)	1
M04.025	protealysin	9
M04.027	Prt1 peptidase (Pectobacterium carotovorum)	1
M05.001	mycolysin	12
M06.001	immune inhibitor A peptidase (Bacillus sp.)	24
M06.002	PrtV peptidase	3
M07.001	snapalysin	4
M08.001	leishmanolysin	20
M09.001	collagenase V (Vibrio spp.)	5
M09.002	collagenase G/A (Clostridium histolyticum)	167		G			G
M09.003	bacterial collagenase H	246		G			G	P
M09.005	collagenase ColT (Clostridium tetani)	281		G			G
M10.001	matrix metallopeptidase-1	91
M10.002	matrix metallopeptidase-8	123
M10.003	matrix metallopeptidase-2	3423
M10.004	matrix metallopeptidase-9	412
M10.005	matrix metallopeptidase-3	2471
M10.006	matrix metallopeptidase-10 (Homo sapiens-type)	103
M10.007	matrix metallopeptidase-11	21
M10.008	matrix metallopeptidase-7	196					L
M10.009	matrix metallopeptidase-12	342
M10.010	envelysin	6
M10.012	GM1-MMP (Glycine max)	3
M10.013	matrix metallopeptidase-13	165		P
M10.014	membrane-type matrix metallopeptidase-1	139
M10.015	membrane-type matrix metallopeptidase-2	14
M10.016	membrane-type matrix metallopeptidase-3	20
M10.017	membrane-type matrix metallopeptidase-4	27
M10.018	matrix metallopeptidase-18	2
M10.019	matrix metallopeptidase-20	43
M10.020	fragilysin	5
M10.021	matrix metallopeptidase-19	8
M10.022	matrix metallopeptidase-23B	1
M10.023	membrane-type matrix metallopeptidase-5	3
M10.024	membrane-type matrix metallopeptidase-6	178
M10.025	HMMP (Hydra vulgaris)-like peptidase	1
M10.029	matrix metallopeptidase-26	17
M10.031	Dm1 matrix metallopeptidase	3
M10.033	collagenase-like A peptidase (rodent)	1
M10.036	Dm2-matrix metallopeptidase	1
M10.038	At5-MMP (Arabidopsis thaliana)	169
M10.039	metallopeptidase II (Bacteroides fragilis)	4
M10.051	serralysin	2
M10.053	peptidase B (Erwinia-type)	1
M10.054	peptidase C (Erwinia-type)	1
M10.056	aeruginolysin	13
M10.057	mirabilysin	32
M10.060	epralysin	10			R	R
M10.063	PrtA peptidase (Photorhabdus-type)	29		E		Y
M10.066	karilysin	38		P			L
M10.A01	At2-MMP (Arabidopsis thaliana)	104
M10.A02	At4-MMP (Arabidopsis thaliana)	183
M10.A04	At1-MMP (Arabidopsis thaliana)	61
M10.A05	At3-MMP (Arabidopsis thaliana)	103
M100.001	spartan peptidase	1
M101.001	flagellinolysin	2
M102.001	DA1 peptidase (Arabidopsis thaliana)	1
M103.001	TldD peptidase (Escherichia coli)	24
M11.001	gametolysin	7
M12.001	astacin	209
M12.002	meprin alpha subunit	776
M12.003	myosinase	2
M12.004	meprin beta subunit	935
M12.005	procollagen C-peptidase	42					D
M12.006	choriolysin L	1
M12.007	choriolysin H	7
M12.008	nephrosin	6
M12.010	tolloid	1
M12.012	blastula protease 10 (Paracentrotus)	1
M12.014	hatching enzyme (Xenopus-type)	6
M12.015	xolloid	1
M12.016	vertebrate tolloid-like 1 protein	17					D
M12.018	mammalian-type tolloid-like 2 protein	6
M12.019	MIG-17 peptidase	1
M12.020	ADAM28 peptidase (mouse-type)	5
M12.021	ADAMTS9 peptidase	2
M12.022	ADAM25 H6	2
M12.024	ADAMTS14 peptidase	3
M12.025	ADAMTS15 peptidase	125
M12.026	ADAMTS16 peptidase	5
M12.032	LAST peptidase (Limulus-type)	78
M12.033	LAST_MAM peptidase (Limulus-type)	432
M12.066	flavastacin	25
M12.131	acutolysin A	2
M12.132	jararafibrase	6
M12.133	fibrolase	3
M12.134	halylysin a	3
M12.136	leucolysin	16				G
M12.137	BHRa hemorrhagin (Bitis arietans)	14
M12.138	jararhagin	40
M12.139	bothrolysin	4
M12.140	bothropasin	62					L
M12.141	adamalysin	7
M12.142	atrolysin A	8
M12.143	atrolysin B	6
M12.144	atrolysin C	60
M12.145	atrolysin E	19					L
M12.146	atrolysin F	6
M12.147	atroxase	5
M12.148	basilysin	5
M12.149	horrilysin	5
M12.150	ruberlysin	16
M12.151	ecarin	4
M12.152	ophiolysin	5
M12.153	fibrinolytic peptidase (Philodryas olfersii)	15					L	V
M12.154	trimerelysin I	8
M12.155	trimerelysin II	12					L
M12.156	trimerelysin IIA	2
M12.157	mucrolysin	14
M12.158	russellysin	7
M12.160	venom metallopeptidase PREH	3
M12.161	kistomin (Calloselasma rhodostoma)	9
M12.162	mutalysin II	7
M12.164	lebetase	14
M12.167	najalysin	3
M12.168	alpha peptidase (Crotalus atrox)	4
M12.169	metallopeptidase B (Bothrops moojeni)	16
M12.170	jararafibrase II (Bothrops jararaca)	2
M12.171	HT-1 peptidase (Crotalus viridis)	7
M12.172	carinactivase	1
M12.173	mocarhagin	4
M12.175	hemorrhagic toxin I (Crotalus ruber)	5
M12.177	multactivase	1
M12.178	brevilysin L6	16					L	L
M12.179	bilitoxin 2 (Agkistrodon bilineatus)	4
M12.182	hemorrhagic metallopeptidase a (Trimeresurus mucrosquamatus)	4
M12.183	hemorrhagic metallopeptidase b (Trimeresurus mucrosquamatus)	2
M12.184	mutalysin I	2
M12.188	ADAMTS20 peptidase (mouse-type)	1
M12.190	ammodytase	6
M12.191	antarease	70
M12.208	ADAM8 peptidase	29
M12.209	ADAM9 peptidase	20
M12.210	ADAM10 peptidase	155
M12.211	Kuzbanian peptidase (non-mammalian)	2
M12.212	ADAM12 peptidase	7
M12.214	ADAM19 peptidase	13					S
M12.215	ADAM15 peptidase	2
M12.216	jerdohagin (Trimeresurus jerdonii)	15
M12.217	ADAM17 peptidase	184
M12.219	ADAMDEC1 peptidase	4
M12.220	ADAMTS3 peptidase	1
M12.221	ADAMTS4 peptidase	506
M12.222	ADAMTS1 peptidase	16				E
M12.224	ADAM28 peptidase (Homo sapiens-type)	6
M12.225	ADAMTS5 peptidase	435
M12.226	ADAMTS8 peptidase	10					L
M12.236	kaouthiagin	2
M12.241	ADAMTS13 peptidase	1
M12.244	ADAM33 peptidase	4
M12.301	procollagen I N-peptidase	4
M12.303	acutolysin C	7
M12.304	jararafibrase III (Bothrops jararaca)	5
M12.305	jararafibrase IV (Bothrops jararaca)	2
M12.306	BHRb haemorrhagin (Bitis arietans)	11
M12.307	halylysin b	6
M12.308	halylysin c	8
M12.309	hemorrhagic toxin I (Gloydius halys blomhoffii)	12					L
M12.310	metallopeptidase MTP-1	18
M12.311	BaP1 peptidase (Bothrops asper)	45
M12.312	neuwiedase (Bothrops neuwiedi)	2
M12.315	halysase	6
M12.320	hemorrhagic factor 3 (Bothrops jararaca)-like peptidase	1
M12.321	TOH-2 peptidase	1
M12.327	leucurolysin-a	25
M12.334	fibrinogenase-2 (Deinagkistrodon acutus)	4
M12.335	baltergin (Bothrops alternatus)	1
M12.338	BmooMPalpha-I (Bothrops sp.)	36				P			Q
M12.345	moojeni peptidase A	10	L
M12.UPB	subfamily M12B unassigned peptidases	11					L
M13.001	neprilysin	124
M13.002	endothelin-converting enzyme 1	34
M13.003	endothelin-converting enzyme 2	17
M13.004	oligopeptidase O1	10
M13.005	oligopeptidase O3	7
M13.008	neprilysin-2	16
M13.009	Zmp1 peptidase (Mycobacterium-type)	10
M13.010	oligopeptidase O2	4
M13.011	MEP peptidase (nematode)	57
M13.012	Nep2 peptidase (insect)	8
M13.014	neprilysin-4 (Drosophila melanogaster)	32
M13.090	Kell blood-group peptidase	7
M13.091	PHEX peptidase	54					D
M14.001	carboxypeptidase A1	22
M14.002	carboxypeptidase A2	11
M14.003	carboxypeptidase B	7
M14.004	carboxypeptidase N	15					KR	0-	0-	0-
M14.005	carboxypeptidase E	24					R
M14.006	carboxypeptidase M	11					KR	0-	0-	0-
M14.007	carboxypeptidase T	2
M14.008	gamma-D-glutamyl-(L)-meso-diaminopimelate peptidase I	3
M14.009	carboxypeptidase B2	19					KR	0-	0-	0-
M14.010	carboxypeptidase A3	7
M14.011	metallocarboxypeptidase D peptidase unit 1	1
M14.012	metallocarboxypeptidase Z	14					R
M14.014	carboxypeptidase MeCPA	5
M14.016	metallocarboxypeptidase D peptidase unit 2	1
M14.017	carboxypeptidase A4	68						0-	0-	0-
M14.018	carboxypeptidase A6	42						0-	0-	0-
M14.020	carboxypeptidase A5	1
M14.023	CPG70 carboxypeptidase (Porphyromonas gingivalis)	27					K	0-	0-	0-
M14.024	insect gut carboxypeptidase-1	2
M14.025	cytosolic carboxypeptidase 5	6
M14.027	cytosolic carboxypeptidase 6	8
M14.028	cytosolic carboxypeptidase 1	17	E		E	E	E	0-	0-	0-
M14.030	cytosolic carboxypeptidase 4	5
M14.031	insect gut carboxypeptidase-2	2
M14.032	insect gut carboxypeptidase-3	4
M14.034	murein peptide amidase MpaA	1
M14.038	PGP1 D,L-carboxypeptidase (Campylobacter jejuni)	2
M15.001	zinc D-Ala-D-Ala carboxypeptidase (Streptomyces-type)	1
M15.002	DD-carboxypeptidase pdcA (Myxococcus-type)	1
M15.003	van XYc peptidase	3
M15.010	vanY D-Ala-D-Ala carboxypeptidase	5
M15.011	vanX D-Ala-D-Ala dipeptidase	5
M15.012	Aad peptidase	1
M15.021	Ply500 L-Ala-D-Glu peptidase	1
M15.022	L-alanyl-D-glutamate peptidase (bacteriophage T5)	1
M15.023	lysin LysA2 (Lactobacillus casei bacteriophage A2) and similar	2
M15.024	DacB metallopeptidase (Streptococcus pneumoniae)	2
M16.001	pitrilysin	23
M16.002	insulysin	101
M16.003	mitochondrial processing peptidase beta-subunit	86			R
M16.004	chloroplast (stromal) processing peptidase	19					A
M16.005	nardilysin	7
M16.007	Axl1 peptidase	1
M16.008	Ste23 peptidase	1
M16.009	eupitrilysin	60
M16.011	falcilysin	10
M16.013	CYM1 peptidase (Saccharomyces cerevisiae)	1
M16.016	YMXG peptidase	40
M16.017	plinsulysin	17
M16.019	YMXG peptidase	5
M17.001	leucyl aminopeptidase 3	2
M17.002	leucyl aminopeptidase (plant-type)	5
M17.003	PepA aminopeptidase	3
M17.004	PepB aminopeptidase	8
M17.008	M17 aminopeptidase (Plasmodium spp.)	8
M17.009	aminopeptidase yspII (Schizosaccharomyces sp.)	4
M17.010	leucyl aminopeptidase (Bacillus-type)	2
M17.011	leucyl aminopeptidase (Fasciola-type)	3
M17.012	PwLAP aminopeptidase	2
M17.013	cysteinylglycinase (Treponema denticola)-like peptidase	3
M17.014	LAPTc aminopeptidase	1
M17.015	aminopeptidase pepZ (Staphylococcus sp.)	16	0-	0-	0-			0-	0-	0-
M18.001	aminopeptidase I	1
M18.002	aspartyl aminopeptidase	10	0-	0-	0-	D
M18.003	aspartyl aminopeptidase (Plasmodium-type)	3
M19.001	membrane dipeptidase	4
M19.003	dipeptidase AC	1
M19.004	membrane-bound dipeptidase-3	1
M19.007	thermostable dipeptidase (Brevibacillus-type)	3
M19.011	dipeptidase 2 homologue (rodent)	1
M20.001	glutamate carboxypeptidase	1
M20.002	Gly-Xaa carboxypeptidase	1
M20.003	peptidase T	12	0-	0-	0-		AG		0-	0-
M20.004	peptidase V	6
M20.005	carnosine dipeptidase II	6
M20.006	carnosine dipeptidase I	17	0-	0-	0-				0-	0-
M20.007	Xaa-His dipeptidase	4
M20.008	carboxypeptidase Ss1	6
M20.010	DapE peptidase	15	0-	0-	0-	D		0-	0-	0-
M20.012	Pep581 peptidase	9
M20.013	Xaa-methyl-His dipeptidase	13	0-	0-	0-			0-	0-	0-
M20.014	indoleacetyl amino acid hydrolase	1
M20.017	Dug1 peptidase	1
M20.020	p-aminobenzoyl-glutamate hydrolase subunit A	2
M20.021	cytosolic beta-alanyl-lysine dipeptidase	6
M23.001	beta-lytic metallopeptidase	15				G
M23.002	staphylolysin	12			G	G
M23.003	Mername-AA291 peptidase	7
M23.004	lysostaphin	6
M23.005	zoocin A	1
M23.007	enterolysin A	2
M23.008	gp13 peptidase (bacteriophage phi-29)	1
M23.009	Mername-AA292 peptidase	2
M23.010	LytH peptidase	1
M23.011	YebA peptidase	1
M23.UPB	subfamily M23B unassigned peptidases	1
M24.001	methionyl aminopeptidase 1 (Escherichia-type)	978	0-	0-	0-	M
M24.002	methionyl aminopeptidase 2	135	0-	0-	0-	M
M24.003	Xaa-Pro dipeptidase (bacteria-type)	13	0-	0-	0-		P	0-	0-	0-
M24.004	aminopeptidase P (bacteria)	9
M24.005	aminopeptidase P2	13	0-	0-			P	P
M24.006	bacillus Xaa-Pro aminopeptidase	9
M24.007	Xaa-Pro dipeptidase (eukaryote-type)	3
M24.008	hyperthermophile prolidase	8
M24.009	aminopeptidase P1	18	0-	0-	0-		P
M24.017	methionyl aminopeptidase 1 (eukaryote)	6
M24.026	aminopeptidase P3	60	0-	0-	0-	Y	S
M24.028	mitochondrial methionyl aminopeptidase	131	0-	0-	0-	M
M24.031	leucine aminopeptidase (Thermotoga-type)	4
M24.032	Mername-AA273 peptidase	3
M24.033	aminopeptidase P (Streptomyces-type)	12	0-	0-	0-		P		0-	0-
M24.034	PH0974 dipeptidase	7
M24.036	methionyl aminopeptidase 1 (Staphylococcus-type)	3
M24.037	At4g36760 g.p. (Arabidopsis thaliana) and similar	4
M24.038	aminopeptidase P (Plasmodium falciparum-type)	22	0-	0-	0-		P
M24.039	YdpF (Escherischia coli)	19	0-	0-	0-
M24.A14	LCP55 (Arabidopsis thaliana)	93				F	S
M26.001	IgA1-specific metallopeptidase	1
M27.001	tentoxilysin	4
M27.002	bontoxilysin	10
M27.003	VAMP-cleaving peptidase (Weissella oryzae)	1
M27.004	botulinum neurotoxin X	6
M27.UPW	family M27 unassigned peptidases	2
M28.001	aminopeptidase Y	28	0-	0-	0-				0-	0-
M28.002	aminopeptidase Ap1	66	0-	0-	0-
M28.003	aminopeptidase S (Streptomyces-type)	10	0-	0-	0-	L			0-	0-
M28.004	aminopeptidase AC	13	0-	0-	0-	F
M28.006	Mername-AA063 peptidase	19	0-	0-	0-
M28.008	secreted aminopeptidase (Pseudomonas-type)	2
M28.009	YwaD peptidase	5
M28.010	glutamate carboxypeptidase II	10	0-	0-		E	E	0-	0-	0-
M28.012	glutamate carboxypeptidase III	3
M28.014	carboxypeptidase Q	33	0-	0-	0-			0-	0-	0-
M28.015	aminopeptidase ES-62 (Acanthocheilonema viteae)	1
M28.019	aminopeptidase SSAP (Streptomyces septatus)	9
M28.020	AM-1 aminopeptidase	5
M28.021	AaaA aminopeptidase	13	0-	0-	0-	R		0-	0-	0-
M28.022	leucine aminopeptidase-1 (Aspergillus fumigatus)	10	0-	0-	0-			0-	0-	0-
M29.001	aminopeptidase T	5
M29.002	aminopeptidase II (Bacillus-type)	6
M29.004	PepS aminopeptidase	1
M29.005	aminopeptidase S (Staphylococcus-type)	2
M30.001	hyicolysin	15
M32.001	carboxypeptidase Taq	14	0-	0-		A		0-	0-	0-
M32.002	carboxypeptidase Pfu	2
M32.003	TcMCP1 carboxypeptidase	27				F
M32.004	TcMCP2 carboxypeptidase (Trypanosoma cruzi)	1
M32.005	LmaCP1 carboxypeptidase (Leishmania major) and similar	13				A		0-	0-	0-
M32.006	ypwA peptidase	4
M34.001	anthrax lethal factor	17
M34.002	Pro-Pro endopeptidase 1 (Clostridium difficile-type)	13	V		N	P	P	V	P	P
M34.003	Pro-Pro endopeptidase 2	3
M35.001	penicillolysin	36
M35.002	deuterolysin	27
M35.004	peptidyl-Lys metallopeptidase	2105					K
M36.001	fungalysin	6
M36.002	neutral protease I (Aspergillus oryzae)	9
M38.001	isoaspartyl dipeptidase (metallo-type)	3
M38.002	Pro-Hyp dipeptidase	9
M38.UPW	family M38 unassigned peptidases	3
M41.001	FtsH peptidase	24
M41.003	m-AAA peptidase	3
M41.004	i-AAA peptidase	1
M41.006	paraplegin	1
M41.007	Afg3-like protein 2	2
M41.013	Ftsh peptidase (Thermus-type)	32
M41.016	Afg3-like protein 1A	1
M42.001	glutamyl aminopeptidase (bacterium)	7
M42.002	aminopeptidase I beta chain (Bacillus-type)	2
M42.003	PhTET1 aminopeptidase	12	0-	0-	0-					0-
M42.004	PhTET2 aminopeptidase	23	0-	0-	0-
M42.005	TET aminopeptidase	12	0-	0-	0-
M42.008	YpdE-type putative peptidase	6
M42.009	PhTET3 aminopeptidase	4
M42.010	CelM peptidase	5
M43.001	cytophagalysin	2
M43.004	pappalysin-1	4
M43.005	pappalysin-2	1
M43.007	ulilysin (Methanosarcina acetivorans)	8
M43.008	Mername-AA293 peptidase	1
M44.001	pox virus metallopeptidase	1
M48.001	Ste24 peptidase	6
M48.003	farnesylated-protein converting enzyme 1	4
M48.018	Oma1 peptidase	3
M48.020	STE24 peptidase (Sarcomastigophora-type)	1
M48.021	metallopeptidase PGM48 (Arabidopsis thaliana)	6
M49.001	dipeptidyl-peptidase III	25
M49.005	Nudix hydrolase 3	6
M49.006	aflatoxin oxidase (Armillariella tabescens)	2
M49.007	dipeptidyl-peptidase III (Caldithrix abyssi)	10	0-	0-				0-	0-	0-
M49.UPW	family M49 unassigned peptidases	2
M50.001	site 2 peptidase	3
M50.002	sporulation factor SpoIVFB	1
M50.004	RseP peptidase	4
M50.009	At4g20310-like peptidase	1
M50.010	PF0167 g.p. (Pyrococcus furiosus)	1
M50.011	RasP peptidase (Bacillus subtilis)	1
M50.UPB	subfamily M50B unassigned peptidases	1
M54.001	archaelysin	4
M54.002	aminopeptidase AMZ2	2
M54.003	aminopeptidase AMZ1	4
M55.001	D-aminopeptidase DppA	8
M56.001	BlaR1 peptidase	2
M60.006	ZmpB peptidase (Clostridium perfringens)	6
M61.001	glycyl aminopeptidase	26	0-	0-	0-
M61.002	BcepAP aminopeptidase (Burkholderia cepacia)	10	0-	0-	0-	D
M64.001	IgA peptidase (Clostridium ramosum-type)	2
M67.001	PSMD14 peptidase	2
M67.002	Csn5 peptidase	4
M67.005	histone H2A deubiquitinase MYSM1	4
M67.006	STAMBP isopeptidase	2
M67.009	Mec peptidase	1
M67.012	desampylase	2
M72.001	peptidyl-Asp metallopeptidase	21					D
M72.002	CpaA g.p. (Acinetobacter baumannii)	2
M73.001	camelysin	11
M74.001	murein endopeptidase	3
M75.001	imelysin	8
M76.002	ATP23 peptidase (Saccharomyces cerevisiae-type)	1
M78.001	ImmA peptidase	1
M85.001	NleC peptidase (Escherichia coli)	2
M86.001	PghP gamma-polyglutamate hydrolase (bacteriophage)	1
M87.001	chloride channel accessory protein 1	6
M87.002	chloride channel accessory protein 4	6
M87.003	chloride channel accessory protein 2	5
M87.004	chloride channel accessory protein 7 (Mus musculus)	1
M87.005	chloride channel accessory protein 4 (Mus musculus)	1
M87.006	chloride channel accessory protein 1 (Mus musculus)	1
M87.UPW	family M87 unassigned peptidases	4
M88.001	IMPa peptidase (Pseudomonas aeruginosa)	1
M90.001	MtfA peptidase	5
M91.001	NleD peptidase (Escherichia coli-type)	1
M95.003	selecase (Methanocaldococcus jannaschii)	1
M98.001	YghJ g.p. (Escherichia coli)	1
M99.001	Csd4 peptidase (Helicobacter pylori)	2
M9A.002	tripeptide aminopeptidase	1
M9A.005	clostridial aminopeptidase	3
M9A.007	Xaa-Trp aminopeptidase	35	0-	0-	0-				0-	0-
M9A.008	tryptophanyl aminopeptidase (Trichosporon cutaneum)	15	0-	0-	0-	W		0-	0-	0-
M9A.009	aminopeptidase X	1
M9A.011	neuron-specific aminopeptidase	10	0-	0-	0-
M9A.012	glycyl aminopeptidase (Actinomucor elegans)	10	0-	0-	0-	G			0-	0-
M9A.013	neuron-specific aminopeptidase-2	9
M9B.001	Xaa-Arg dipeptidase	1
M9B.004	Met-Xaa dipeptidase	14	0-	0-	0-	M		0-	0-	0-
M9D.001	peptidyl-dipeptidase B	5
M9D.002	proline-specific peptidyl-dipeptidase (Streptomyces)	2
M9E.002	alanine carboxypeptidase	3
M9E.003	mitochondrial carboxypeptidase	1
M9E.004	membrane Pro-Xaa carboxypeptidase	20				P		0-	0-	0-
M9E.007	carboxypeptidase G3	12	0-	0-			E	0-	0-	0-
M9G.003	acrolysin	3
M9G.005	succinyl-tri-alanyl-p-nitroaniline hydrolase	3
M9G.009	neutral endopeptidase (Aspergillus oryzae)	6
M9G.010	FALGPA-peptidase (Treponema denticola)	3
M9G.018	neutral endopeptidase (Micrococcus caseolyticus)	12					F
M9G.021	metallopeptidase QG (Escherichia coli)	1
M9G.022	peptidase Ci (Escherichia coli)	9
M9G.025	magnolysin	1
M9G.026	dactylysin	23
M9G.028	magaininase	4
M9G.030	dynorphin-processing endopeptidase (metallo-type)	3
M9G.031	cyclic peptidase (Lactocobacillus)	1
M9G.034	metallopeptidase ShpII (Staphylococcus hyicus)	21
M9G.036	gonadotropin beta-subunit nicking enzyme	1
M9G.040	hepatitis B virus binding factor	1
M9G.041	aharin	2
M9G.047	insulin-cleaving periplasmic peptidase (Acinetobacter calcoaceticus)	7
M9G.051	ZPA-processing enzyme	1
M9G.054	extracellular metallopeptidase (Pseudomonas fluorescens M3/6)	1
M9G.055	dispase (Paenibacillus/Bacillus polymyxa)	2
N01.001	nodavirus peptide lyase	2
N02.001	tetravirus coat protein	1
N04.001	Tsh-associated self-cleaving domain (Escherichia coli) and similar	1
N04.UPW	family N4 unassigned peptide lyases	1
N06.001	YscU protein	1
N06.002	SpaS protein (Salmonella sp.)	2
N06.003	EscU protein (Escherichia coli)	1
N06.004	HrcU protein (Xanthomonas sp.)	1
N07.001	reovirus type 1 coat protein	1
N08.001	poliovirus capsid VP0-type self-cleaving protein	40	P	A	L	N	S	P
N09.001	intein-containing V-type proton ATPase catalytic subunit A	45		VY	HV	GN	C		E
N10.002	intein-containing replicative DNA helicase precursor	160			H	N	C
N10.003	intein-containing DNA polymerase III subunit alpha precursor	2
N10.004	intein-containing translation initiation factor IF-2 precursor	51			GH	N	C			P
N10.005	intein-containing DNA polymerase II large subunit DP2 precursor Mername-AA281	26					C	F
N10.006	intein-containing DNA polymerase II large subunit DP2 precursor Mername-AA282	18	K	R	GR	NQ	C	DF	G	D
N10.007	intein-containing DNA-dependent DNA polymerase precursor	2
N11.001	intein-containing chloroplast ATP-dependent peptide lyase	2
P01.001	DmpA aminopeptidase	44
P01.003	BapF peptidase (Pseudomonas sp.)	5
P02.001	EGF-like module containing mucin-like hormone receptor-like 2	1
P02.010	latrophilin-1	1
P02.011	latrophilin 3	1
P02.038	KIAA1879 protein	1
S01.001	chymotrypsin A (cattle-type)	1059
S01.005	mast cell peptidase 4 (Rattus)	40		V	W	F		G
S01.010	granzyme B (Homo sapiens-type)	1902				D
S01.011	testisin	12			P	R
S01.013	Nudel peptidase	1
S01.015	tryptase beta	65				K
S01.017	kallikrein-related peptidase 5	75				R
S01.019	corin	3
S01.020	kallikrein-related peptidase 12	20				KR				G
S01.021	DESC1 peptidase	111				R
S01.023	flavoxobin	1
S01.025	mast cell peptidase 6 (mouse numbering)	2
S01.026	mast cell peptidase 7 (mouse numbering)	3
S01.028	tryptase gamma 1	5
S01.029	kallikrein-related peptidase 14	79				R
S01.031	peptidase 9 (Dermatophagoides-type)	3
S01.033	factor VII-activating peptidase	15				R
S01.034	transmembrane peptidase, serine 4	10				R
S01.035	brachyurin-T	2
S01.039	kallikrein 1-related peptidase b22 (Mus musculus)	7
S01.040	chymotrypsin-like enzyme (Lepidoptera)	1
S01.041	kallikrein 1-related peptidase b11	3
S01.042	intestinal serine peptidase (rodent)	6
S01.047	human airway trypsin-like peptidase	100				R
S01.052	kallidin-releasing enzyme (Bitis arietans)	6
S01.069	kallikrein 1-related peptidase b24 (Mus musculus)	1
S01.070	kallikrein 1-related peptidase b26 (Mus musculus)	1
S01.071	kallikrein 1-related peptidase b9 (Mus musculus)	14				R
S01.072	matriptase-3	114				R
S01.073	kallikrein 1-related peptidase b27 (Mus musculus)	2
S01.074	marapsin	3
S01.075	tryptase-6	5
S01.079	transmembrane peptidase, serine 3	1
S01.081	kallikrein-related peptidase 15	1380				R
S01.082	spermosin (Halocynthia roretzi)	1
S01.086	30kP peptidase A (Bombyx-type)	8
S01.087	TMPRSS13 peptidase	4
S01.090	hypodermin B	5
S01.094	trypsin 1 (Rattus-type)	3
S01.095	vascular chymase (Rattus norvegicus)	6
S01.096	granzyme B (Equus-type)	1
S01.101	trypsin (Streptomyces griseus-type)	8
S01.102	trypsin (Streptomyces erythraeus-type)	2
S01.103	trypsin (fungal)	2
S01.108	tryptase-5	4
S01.109	astrovirus serine peptidase	1
S01.110	trypsin alpha (insect)	1
S01.111	hypodermin A	4
S01.112	cocoonase	6
S01.113	vitellin-degrading peptidase (Bombyx-type)	1
S01.118	tryptase (mammalian, non-Homo sapiens-type)	2
S01.120	trypsin-2 type B	3
S01.121	hypodermin C	8
S01.122	brachyurin-C	36
S01.123	euphauserase	1
S01.124	trypsin Y	2
S01.125	trypsin-1 (fish)	4
S01.126	trypsin-3 (fish)	1
S01.127	cationic trypsin (Homo sapiens-type)	8
S01.131	elastase-2	488
S01.132	mannan-binding lectin-associated serine peptidase-3	8
S01.133	cathepsin G	465
S01.134	myeloblastin	55
S01.135	granzyme A	441				R
S01.136	granzyme B, rodent-type	493				D
S01.137	granzyme C	19
S01.139	granzyme M	1369				L
S01.140	chymase (Homo sapiens-type)	107
S01.141	mast cell peptidase 1 (Rattus-type)	7
S01.142	duodenase	19
S01.143	tryptase alpha	23				KR
S01.144	cercarial elastase (Schistosoma sp.)	3
S01.145	mastin	1
S01.146	granzyme K	20				R
S01.147	granzyme H	8
S01.149	mast cell peptidase 4 (mouse numbering)	11
S01.150	mast cell peptidase 5 (mouse numbering)	44				V
S01.151	trypsin 1	22992				KR
S01.152	chymotrypsin B	26
S01.153	elastase-1	51
S01.154	pancreatic endopeptidase E	3
S01.155	pancreatic elastase II	19
S01.156	enteropeptidase	21			D	R			G
S01.157	chymotrypsin C	46
S01.159	prostasin	6
S01.160	kallikrein 1	31
S01.161	kallikrein-related peptidase 2	66				R
S01.162	kallikrein-related peptidase 3	86
S01.163	kallikrein 1-related peptidase b16 (Mus musculus)	2
S01.164	kallikrein 1-related peptidase b1	3
S01.165	kallikrein 1-related peptidase c10 (Rattus norvegicus)	5
S01.167	kallikrein 1 (Mus musculus)	4
S01.170	kallikrein 1-related peptidase b3	3
S01.172	kallikrein 1-related peptidase c2 (Rattus norvegicus)	21				R
S01.173	kallikrein 13 (Mus musculus)	7
S01.174	mesotrypsin	22				R
S01.176	batroxobin	2
S01.177	crotalase	2
S01.178	ancrod	3
S01.179	bothrombin	1
S01.180	platelet-aggregating venom peptidase	4
S01.181	bilineobin	1
S01.183	trypsin IV (Rattus norvegicus)	3
S01.184	factor V activator (Daboia russellii)	1
S01.186	snake venom plasminogen activator	5
S01.187	peptidase 6 (Dermatophagoides sp.)	2
S01.188	capillary permeability-increasing enzyme-2 (Gloydius-type)	4
S01.189	complement component C1r-like peptidase	1
S01.191	complement factor D	3
S01.192	complement component activated C1r	7
S01.193	complement component activated C1s	20				R
S01.194	complement component C2a	9
S01.196	complement factor Bb	8
S01.198	mannan-binding lectin-associated serine peptidase 1	8
S01.199	complement factor I	7
S01.200	Snake peptidase (Insecta)	1
S01.201	Easter peptidase	1
S01.204	prophenoloxidase-activating peptidase-I	1
S01.211	coagulation factor XIIa	7
S01.212	plasma kallikrein	40				R
S01.213	coagulation factor XIa	12				R
S01.214	coagulation factor IXa	12			G	R
S01.215	coagulation factor VIIa	9
S01.216	coagulation factor Xa	63				R
S01.217	thrombin	195				R
S01.218	protein C (activated)	15				R
S01.219	coagulation factor C (Limulus, Tachypleus), activated	4
S01.220	coagulation factor B (Limulus, Tachypleus), activated	4
S01.221	clotting enzyme (Tachypleus-type)	4
S01.222	coagulation factor G, activated	4
S01.223	acrosin	6
S01.224	hepsin	110				R
S01.228	hepatocyte growth factor activator	2
S01.229	mannan-binding lectin-associated serine peptidase 2	8
S01.231	urokinase-type plasminogen activator	19				R
S01.232	t-plasminogen activator	9
S01.233	plasmin	132				KR
S01.234	peptidase 3 (Dermatophagoides-type)	3
S01.235	acutobin	3
S01.236	kallikrein-related peptidase 6	82				R
S01.237	neurotrypsin	3
S01.239	plasminogen activator (Desmodus-type)	1
S01.240	ovochymase-2	3
S01.243	lumbrokinase	25				R
S01.244	kallikrein-related peptidase 8	25				R
S01.245	ovochymase domain 3	1
S01.246	kallikrein-related peptidase 10	2
S01.247	epitheliasin	21				R
S01.251	kallikrein-related peptidase 4	123				R
S01.252	prosemin	2
S01.253	halystase	6
S01.256	chymopasin	6
S01.257	kallikrein-related peptidase 11	16				R				G-
S01.258	trypsin-2 type A	9
S01.261	streptogrisin A	6
S01.262	streptogrisin B	14		A
S01.265	streptogrisin C	1
S01.266	streptogrisin D	5
S01.267	streptogrisin E	23		A	A	E	V	F		D
S01.268	alpha-lytic endopeptidase	9
S01.269	glutamyl endopeptidase I	4330				E
S01.271	glutamyl peptidase BL	72				E
S01.273	DegP peptidase	16				V
S01.274	DegQ peptidase	7
S01.275	DegS peptidase	6
S01.276	yeast-lytic peptidase	5
S01.277	HtrA1 peptidase (Homo sapiens-type)	5
S01.278	HtrA2 peptidase	235
S01.280	lysyl endopeptidase (bacteria)	809				K
S01.281	arginyl peptidase	11				R
S01.282	SplB peptidase (Staphylococcus aureus)	19	W	E	L	Q		S
S01.286	Tysnd1 peptidase	1
S01.294	HAT-like 3 peptidase	11				R
S01.300	kallikrein-related peptidase 7	43
S01.302	matriptase	119				R
S01.303	mast cell peptidase-11 (rodent)	6
S01.305	prophenoloxidase-activating peptidase (Bombyx-type)	1
S01.306	kallikrein-related peptidase 13	21				R
S01.307	kallikrein-related peptidase 9	1
S01.308	matriptase-2	162				R
S01.311	LCLP peptidase	1
S01.312	SplE peptidase (Staphylococcus aureus)	27			L				0-	0-
S01.313	spinesin	2
S01.335	calobin	3
S01.339	cerastotin	3
S01.340	serpentokallikrein-1 (Trimeresurus mucrosquamatus)	1
S01.346	okinaxobin I	3
S01.347	contortrixobin	6
S01.353	KN-BJ peptidase 1 (Bothrops jararaca)	7
S01.356	afaacytin (Cerastes cerastes)	3
S01.357	polyserase-IA unit 1	11				R
S01.358	polyserase-IA unit 2	2
S01.364	HtrA-like peptidase (Listeria-type)	2
S01.392	allergen Sar s 3	5
S01.405	kallikrein 1 (Rattus sp.)	10			F	R
S01.407	kallikrein 1-related peptidase c9 (Rattus sp.)	14				R
S01.408	elastase A	4
S01.409	blarinasin	7
S01.412	CHY1 peptidase (Metarhizium anisopliae)	3
S01.413	prophenoloxidase-activating peptidase (Pacifastacus leniusculus)	3
S01.420	prothrombin activator (Lonomia sp.)	3
S01.422	fibrinolytic enzyme A (Annelida-type)	19
S01.423	SprE glutamyl peptidase	3
S01.425	trocarin D	4
S01.428	LV-Ka peptidase	4
S01.430	gabonase (Bitis gabonica)	4
S01.431	SFase-2 endopeptidase	1
S01.432	rhombeobin (Lachesis muta rhombeata )	4
S01.433	peptidase A (Bothrops-type)	4
S01.438	fire ant chymotrypsin	17			P	F		0-	0-	0-
S01.443	glutamyl peptidase BI	14				E
S01.444	hemolymph proteinase 14	2
S01.446	pseutarin C	9
S01.452	blarina toxin (Blarina brevicauda)	2
S01.458	chymase 1 (Mus musculus-type)	44				F	S
S01.462	Spatzle-processing enzyme (Drosophila sp.)	1
S01.463	LV-PA peptidase (Lachesis muta muta)	2
S01.464	OET-03 peptidase (Homarus americanus)	1
S01.466	ACC-C peptidase	1
S01.467	hemolymph proteinase 21	2
S01.479	peptidase Ba III 4 (Bothrops atrox)	1
S01.480	HtrA peptidase (Chlamydia trachomatis-type)	14
S01.481	harobin	5
S01.492	venom serine peptidase (Hymenoptera)	2
S01.494	Htra2 peptidase (Mycobacterium-type)	39
S01.499	alkaline endopeptidase (Nesterenkonia sp.)	9
S01.501	DEG15 peptidase	2
S01.503	SplA peptidase (Staphylococcus aureus)	23				Y
S01.515	VesA peptidase (Vibrio cholerae)	1
S01.516	VesB peptidase (Vibrio cholerae)	1
S01.517	VesC peptidase (Vibrio cholerae)	1
S01.524	kangshuanmei peptidase	4
S01.526	SplD peptidase (Staphylococcus aureus)	22		Y			S
S01.527	pepK (Porphyromonas gingivalis)	1
S01.529	elastase-1 (Trichinella spiralis)	1
S01.975	macrophage-stimulating protein	1
S01.UPA	subfamily S1A unassigned peptidases	14				R
S03.001	togavirin	2
S06.001	IgA1-specific serine peptidase (Neisseria-type)	6
S06.002	EspP peptidase (Escherichia coli)	4
S06.004	Sat peptidase	1
S06.005	Pic peptidase	9
S06.006	Hap serine peptidase	4
S06.007	IgA1-specific serine peptidase type 1 (Haemophilus sp.)	3
S06.008	IgA1-specific serine peptidase type 2 (Haemophilus sp.)	1
S06.009	EatA peptidase Mername-AA278 (Escherichia coli)	6
S07.001	flavivirin	29				R
S07.003	Zika virus NS2B-NS3 peptidase	2
S08.001	subtilisin Carlsberg	43
S08.003	subtilisin lentus	16
S08.004	wprA g.p. (Bacillus-type)	1
S08.005	endopeptidase Q	8
S08.007	thermitase	13
S08.008	Mername-AA053 peptidase	16
S08.009	subtilisin Ak1	12
S08.010	M-peptidase	14
S08.012	PfSUB1 peptidase	23	V		AG
S08.013	subtilisin-like peptidase 2 (Plasmodium-type)	3
S08.014	ALE1 peptidase	16
S08.017	bacillopeptidase F	9
S08.019	lactocepin I	102
S08.020	C5a peptidase	2
S08.022	bpr peptidase (Dichelobacter nodosus)	12
S08.023	apr5 peptidase (Dichelobacter nodosus)	6
S08.024	dentilisin	17
S08.025	allergen 13 (Penicillium sp.)	2
S08.027	cell envelope peptidase A (Streptococcus-type)	4
S08.028	high alkaline protease (Alkaliphilus transvaalensis)	28
S08.029	thermicin	6
S08.030	IspA peptidase	3
S08.031	bli-4 g.p. (Caenorhabditis sp.)	4
S08.032	Psp3 peptidase	4
S08.034	subtilisin BPN'	17
S08.036	subtilisin E	4
S08.037	subtilisin DY	16	A	A	P	F		0-	0-	0-
S08.039	PCSK9 peptidase	3
S08.040	apr2 peptidase (Dichelobacter nodosus)	7
S08.041	perkinsin	1
S08.043	HreP peptidase (Yersinia enterocolitica)	1
S08.046	subtilisin aprM	4
S08.047	KPC1-type peptidase	2
S08.048	furin-1 (arthropod-type)	6
S08.049	furin-2 (insect)	4
S08.050	secreted peptidase A	1
S08.051	aqualysin 1	11
S08.052	cerevisin	21
S08.053	oryzin	3
S08.054	endopeptidase K	47
S08.056	cuticle-degrading peptidase of parasitic fungus	14
S08.057	thermomycolin	28
S08.059	NisP (Lactococcus lactis)-type lantibiotic leader peptidase	4
S08.060	EpiP lantibiotic leader peptidase	1
S08.061	peptidase T	1
S08.063	site-1 peptidase	31	R		L	L
S08.065	MutP (Streptococcus mutans)-type lantibiotic leader peptidase	2
S08.069	SAM-P45 peptidase	1
S08.070	kexin	192			K	R
S08.071	furin	220	R			R
S08.072	PCSK1 peptidase	97			K	R
S08.073	PCSK2 peptidase	205			K	R
S08.074	PCSK4 peptidase	103	R			R
S08.075	PCSK6 peptidase	105	R		K	R
S08.076	PCSK5 peptidase	129	R			R
S08.077	PCSK7 peptidase	116	R			R
S08.079	PrcA peptidase	4
S08.085	PepP lantibiotic leader peptidase	1
S08.086	CylA lantibiotic leader peptidase	1
S08.087	EciP lantibiotic leader peptidase (Staphylococcus epidermidis)	2
S08.090	tripeptidyl-peptidase II	8
S08.091	tripeptidyl-peptidase S	2
S08.092	cucumisin	32
S08.093	LasP lantibiotic leader peptidase (Lactobacillus sakei)	1
S08.095	ElkP lantibiotic leader peptidase	1
S08.097	peptidase C1	6
S08.098	subtilisin sendai	6
S08.099	halophilic peptidase (Halobacillus sp. SR5-3)	2
S08.101	halolysin 1	9
S08.102	halolysin R4	3
S08.108	CspB peptidase (Clostridium sp.)	1
S08.109	KPC2-type peptidase	115			K	R
S08.110	keratinase K1 (Stenotrophomonas maltophilia)	8
S08.112	ARA12 peptidase	53	F	A	P	F	G	G	G
S08.114	peptidase Vpr (Bacillus-type)	1
S08.116	lactocepin-3	158
S08.120	cuticle-degrading peptidase of nematode-trapping fungus	3
S08.121	cytotoxin SubAB	1
S08.123	KP-43 peptidase	1
S08.124	ASUB peptidase	3
S08.125	AspA (Aeromonas sobria)-type peptidase	4
S08.127	TagC peptidase (Dictyostelium discoideum)	2
S08.129	Tk-subtilisin	1
S08.130	MCP-01 peptidase	6
S08.135	tengconlysin	19
S08.137	AprX peptidase (Bacillus sp.)	1
S08.142	collagenolytic endopeptidase (Geobacillus sp. MO-1)	11
S08.145	sporangin	6
S08.146	PatG peptidase	1
S08.148	keratinase (Doratomyces microsporus)	19
S08.149	CDF peptidase	5
S08.150	phytaspase	5
S08.151	SlSBT3 g.p. (Solanum lycopersicum)	19
S08.153	prtR peptidase (Lactobacillus rhamnosus)	1
S08.154	SUB2 g.p. (Toxoplasma gondii)	1
S08.156	PatA peptidase (Prochloron didemni )	1
S08.160	NalP g.p. (Neisseria meningitidis)	1
S08.162	EprS g.p. (Pseudomonas aeruginosa)	12				R		0-	0-	0-
S08.A21	At5g59120 (Arabidopsis thaliana)	2
S09.001	prolyl oligopeptidase	59				P
S09.002	prolyl oligopeptidase homologue (Pyrococcus-type)	3
S09.003	dipeptidyl-peptidase IV (eukaryote)	35				P
S09.004	acylaminoacyl-peptidase	14
S09.005	dipeptidyl aminopeptidase A	14	0-	0-		AP
S09.006	dipeptidyl aminopeptidase B (fungus)	7
S09.007	fibroblast activation protein alpha subunit	10			G	P				Q
S09.008	dipeptidyl peptidase 4 (Aspergillus-type)	8
S09.009	dipeptidyl-peptidase 4 (bacteria-type 1)	5
S09.010	oligopeptidase B	42				R
S09.012	dipeptidyl-peptidase 5	7
S09.013	dipeptidyl-peptidase 4 (bacteria-type 2)	18				P
S09.017	prolyl tripeptidyl peptidase	13	0-			P
S09.018	dipeptidyl-peptidase 8	10	0-	0-		P
S09.019	dipeptidyl-peptidase 9	15	0-	0-		P
S09.021	glutamyl endopeptidase C	15				E
S09.031	AlbD protein (Pantoea dispersa)	2
S09.032	sphingopyxin I lasso peptide isopeptidase	10	0-	0-	0-	G	D	E	D	Q
S09.035	lasso peptide isopeptidase (Asticcacaulis-type)	1
S09.036	Rv0457c peptidase (Mycobacterium tuberculosis)	2
S09.057	apsC g.p. (Aspergillus niger N400)	3
S09.069	omega peptidase (Drosophila melanogaster)	18	0-			AP
S09.070	acylaminoacyl peptidase (Aeropyrum-type)	14				F
S09.072	puromycin hydrolase	17	0-	0-	0-			0-	0-	0-
S09.073	Xaa-Pro dipeptidylpeptidase	19	0-	0-	V	P			0-	0-
S09.075	dipeptidyl-peptidase 5 (Porphyromonas sp.)	7
S09.076	prolyl oligopeptidase (Myxococcus xanthus)	2
S09.077	prolyl oligopeptidase B (Galerina marginata)	3
S09.078	peptide cyclase 1	36	P	V	W	A	F	Q	A	K
S09.079	S9dr carboxypeptidase (Deinococcus radiodurans)	7
S09.A02	At1g76140 (Arabidopsis thaliana)-type peptidase	1
S09.UPA	subfamily S9A unassigned peptidases	3
S10.001	carboxypeptidase Y	17	0-	0-		A		0-	0-	0-
S10.002	serine carboxypeptidase A	10				F
S10.004	serine carboxypeptidase C	18	0-	0-		A		0-	0-	0-
S10.005	serine carboxypeptidase D	16	0-	0-		A		0-	0-	0-
S10.006	Mername-AA083 peptidase	72						0-	0-	0-
S10.007	kex carboxypeptidase	9
S10.008	carboxypeptidase OcpA	14	0-	0-		A		0-	0-	0-
S10.009	serine carboxypeptidase III (plant)	16	0-	0-		A		0-	0-	0-
S10.010	serine carboxypeptidase Z (Absidia zachae) and similar	16							0-	0-
S10.014	carboxypeptidase O	90							0-	0-
S10.UPW	family S10 unassigned peptidases	31							0-	0-
S11.001	D-Ala-D-Ala carboxypeptidase A	4
S11.002	murein-DD-endopeptidase	1
S11.004	K15-type DD-transpeptidase	2
S11.006	D,D-carboxypeptidase PBP3 (Streptococcus-type)	1
S11.007	penicillin-binding protein 4 (Neisseria-type) peptidase	2
S11.008	penicillin-binding protein 5-type peptidase	7
S11.011	D-alanyl-D-alanine carboxypeptidase (Mycobacterium smegmatis)	2
S12.001	D-Ala-D-Ala carboxypeptidase B	11	0-					0-	0-	0-
S12.002	aminopeptidase DmpB	17	0-	0-	0-					0-
S12.003	alkaline D-peptidase	12	0-						0-	0-
S12.008	Pab87 peptidase	1
S12.009	microcystinase MlrB	1
S12.012	AmpH protein (Escherichia-type)	2
S12.013	paenidase	3
S13.001	D-Ala-D-Ala peptidase C	1
S13.002	D-Ala-D-Ala carboxypeptidase (Actinomadura-type)	9
S13.004	penillin-binding protein 4	1
S13.005	Bd3459 D-alanyl-D-alanine carboxypeptidase (Bdellovibrio bacteriovorus)	1
S14.001	peptidase Clp (type 1)	15	A					L	V
S14.002	peptidase Clp (type 2)	1
S14.003	peptidase Clp (type 3)	10	A			M	A	L	V	P
S14.011	PFC0310c peptidase	1
S15.001	Xaa-Pro dipeptidyl-peptidase	10	0-	0-		P
S16.001	Lon-A peptidase	21
S16.002	PIM1 peptidase	8
S16.007	LonC peptidase	2
S16.012	SepM peptidase (Streptococcus mutans)	1
S16.013	CRISPR-associated Lon protease	1
S21.001	assemblin	5
S21.002	cytomegalovirus assemblin	13		V		A	S
S21.003	Epstein-Barr virus-type assemblin	4
S21.004	herpesvirus 6-type assemblin	4
S21.005	Varicella zoster assemblin	2
S21.006	herpesvirus 8-type assemblin	2
S24.001	repressor LexA	4
S24.003	UmuD protein	1
S24.UPW	family S24 unassigned peptidases	4
S26.001	signal peptidase I	347		A		A
S26.002	mitochondrial inner membrane peptidase 1	5
S26.003	signal peptidase SipS	2
S26.004	signal peptidase SipT	1
S26.008	thylakoidal processing peptidase	52		A		A
S26.010	signalase (animal) 21 kDa component	363				A
S26.011	signal peptidase SipW (Bacillus-type)	1
S26.012	mitochondrial inner membrane peptidase 2	1
S26.014	TraF peptidase	1
S26.015	Streptococcus-type signal peptidase	6
S26.016	SpsB signal peptidase	49		A		A
S28.001	lysosomal Pro-Xaa carboxypeptidase	11				P		0-	0-	0-
S28.002	dipeptidyl-peptidase II	30	0-	0-		P
S28.005	PRO1 g.p. (Plasmodiophora brassicae)	1
S29.001	hepacivirin	6
S30.001	potyvirus P1 peptidase	2
S30.002	clover yellow vein potyvirus-type P1 peptidase	1
S31.001	pestivirus NS3 polyprotein peptidase	4
S32.001	equine arteritis virus serine peptidase	15				E	G
S32.002	porcine reproductive and respiratory syndrome virus nsp4 peptidase	10			L	E	G
S33.001	prolyl aminopeptidase	6
S33.002	tripeptidyl-peptidase A	5
S33.004	prolyl dipeptidase (Lactobacillus-type)	18	0-	0-	0-	P			0-	0-
S33.005	tricorn interacting factor F1	16						0-	0-	0-
S33.006	tripeptidyl-peptidase B	1
S33.007	tripeptidyl-peptidase C	1
S33.008	prolyl aminopeptidase 2	10	0-	0-	0-	P
S33.010	SCO7095-type peptidase	11				R		0-	0-	0-
S33.021	iminopeptidase I (Lactobacillus delbrueckii) and similar	1
S33.023	Hip1 peptidase (Mycobacterium tuberculosis)	5
S37.001	PS-10 peptidase	3
S39.001	sobemovirus peptidase	5
S41.001	C-terminal processing peptidase-1	9
S41.002	C-terminal processing peptidase-2	2
S41.006	tricorn core peptidase (bacteria)	9
S41.007	ctpB peptidase	18
S41.011	chlamydial protease-like activity factor	700
S41.013	CtpA peptidase (Borrelia-type)	2
S45.001	penicillin G acylase precursor	3
S46.001	dipeptidyl-peptidase 7 (Porphyromonas gingivalis-type)	29
S46.002	dipeptidyl-peptidase 11 (Porphyromonas gingivalis-type)	10	0-	0-		D
S46.004	BF9343_2924 g.p. (Bacteroides sp.)	1
S49.001	signal peptide peptidase A (Pseudomonas aeruginosa)	7
S49.003	protein C (bacteriophage lambda)	1
S49.005	archaean signal peptide peptidase 1	7
S50.001	infectious pancreatic necrosis birnavirus Vp4 peptidase	8
S50.002	avian infectious bursal disease birnavirus Vp4 peptidase	5
S50.003	Drosophila X virus Vp4 peptidase	2
S50.004	blotched snakehead birnavirus Vp4 peptidase	38			A	A	AE	A		M
S51.001	dipeptidase E	7
S51.003	cyanophycinase	1
S53.001	sedolisin	22	P	A	K	F		R	L
S53.002	sedolisin-B	47	P	I	E	F		R	L	0-
S53.003	tripeptidyl-peptidase I	45
S53.004	kumamolisin	11					Y
S53.005	kumamolisin-B	61	P	I		F		R	L	0-
S53.006	physarolisin	11
S53.007	aorsin	10		L		R
S53.009	kumamolisin-As	1
S53.010	grifolisin	13
S53.011	scytalidolisin	20					A	A
S54.002	rhomboid-like protein 2	1
S54.004	AarA peptidase	58	I	A	T	A	A	F	G	S
S54.007	Pcp1 peptidase (yeast)	2
S54.009	PARL peptidase	3
S54.014	rhomboid YqgP peptidase	4
S54.016	GlpG peptidase (Escherichia-type)	7
S54.017	ROM4 peptidase (Plasmodium-type)	1
S55.001	SpoIVB peptidase	3
S59.001	nucleoporin 145	1
S59.002	nuclear pore complex component Nup145 (Saccharomyces-type)	1
S59.A07	nup189 (Schizosaccharomyces pombe)	1
S60.001	lactoferrin	7
S60.972	serotransferrin precursor (domain 1)	4
S65.001	picornain-like serine peptidase (Breda-1 torovirus)	2
S66.001	murein tetrapeptidase LD-carboxypeptidase (Pseudomonas-type)	1
S66.002	murein tetrapeptidase LD-carboxypeptidase (Escherichia-type)	6
S68.001	PIDD auto-processing protein unit 1	2
S69.001	Tellina virus 1 VP4 peptidase	6
S71.001	MUC1 self-cleaving mucin	1
S72.001	dystroglycan	1
S73.001	gpO peptidase (Enterobacteria phage P2)	1
S74.001	Escherichia coli phage K1F endosialidase CIMCD self-cleaving protein	1
S74.003	myelin regulatory factor	1
S75.001	White bream virus serine peptidase	4
S77.001	prohead peptidase gp21 (bacteriophage T4)	15				E
S79.001	CARD8 self-cleaving protein	1
S80.001	prohead peptidase gp175 (Pseudomonas aeruginosa phage phiKZ)	25		S		E
S80.002	SPN3US prohead peptidase ((Salmonella) myovirus)	3
S81.001	destabilase	4
S82.001	autocrine proliferation repressor protein A (Dictyostelium discoideum)	1
S85.001	small protease (Pseudomonas aeruginosa)	4
S9F.001	peptidyl-glycinamidase	5
S9G.012	tryase	14				R
S9G.013	guanidinobenzoatase	1
S9G.014	clipsin	2
S9G.023	ingobsin	4
S9G.025	snake venom coagulation factor X activator, serine-type (Bungarus fasciatus, Cerastes vipera, Ophiophagus hannah)	6
S9G.031	leucyl endopeptidase (Spinacia oleracea)	2
S9G.034	metridin	9
S9G.038	endopeptidase So	1
S9G.041	peptidase V (Escherichia coli)	7
S9G.054	profilaggrin endopeptidase 1	4
S9G.055	thermostable serine endopeptidase (Sulfolobus)	2
S9G.058	beta-secretase Matsumoto	2
S9G.062	thrombocytin	4
S9G.064	archealysin	8
S9G.069	apoptotic serine peptidase AP24	1
S9G.087	jerdonobin (Trimeresurus jerdonii)	2
S9G.088	jerdofibrase (Trimeresurus jerdonii)	4
S9G.089	flavovilase (Trimeresurus flavoviridis)	2
S9G.093	MSP 1 endopeptidase (Bothrops moojeni)	8
S9G.094	MSP 2 endopeptidase (Bothrops moojeni)	8
S9G.100	okinaxobin II (Trimeresurus okinavensis)	2
S9G.103	PofibS endopeptidase (Philodryas olfersii)	5
S9G.107	seaprose (Aspergillus melleus)	3
S9G.111	milin (Euphorbia milii)	3
S9G.114	CP790 peptidase (Lactobacillus helveticus CP790)	32
S9G.116	wrightin (Wrightia tinctoria)	1
S9G.117	coagulant peptidase (Trimeresurus flavoviridis)	3
S9G.118	Nysius proteinase	11		P		Q		Q
S9G.119	CLE-processing peptidase	1
T01.002	archaean proteasome, beta component	4
T01.005	bacterial proteasome, beta component	1
T01.006	HslV component of HslUV peptidase	3
T01.007	CodW component of CodWX peptidase	1
T01.010	proteasome subunit beta1c	43
T01.011	proteasome subunit beta2c	32				R
T01.012	proteasome subunit beta5c	221
T01.013	proteasome subunit beta1i	1
T01.015	proteasome subunit beta5i	1
T01.018	PfHslV peptidase	3
T01.021	TbHslUV peptidase	1
T02.001	glycosylasparaginase precursor	9
T02.002	isoaspartyl dipeptidase (threonine type)	17	0-	0-	0-	D			0-	0-
T02.004	taspase-1	5
T03.001	gamma-glutamyltransferase 1 (bacterial-type)	3
T03.006	gamma-glutamyltransferase 1 (mammalian-type)	3
T03.023	CapD poly-gamma-glutamate hydrolase	1
T05.001	ornithine acetyltransferase precursor	1
T05.002	ArgJ protein (archea)	1
T07.001	CwpV (Clostridium difficile) self-cleaving threonine peptidase	1
U40.001	protein P5 murein endopeptidase (bacteriophage phi-6)	1
U49.001	Lit peptidase	1
U69.001	AIDA-I self-cleaving autotransporter protein (Escherichia coli)	1
U72.001	Dop isopeptidase	1
U74.001	neprosin	110
U9B.003	Glu-Glu dipeptidase	1
U9B.004	peptidyl-D-amino acid hydrolase (cephalopod)	13	0-	0-	0-	G		0-	0-	0-
U9B.005	LD-dipeptidase (Bacillus sphaericus)	8
U9C.001	dipeptidylaminopeptidase dDAP	3
U9F.002	N-formylmethionyl-peptidase	3
U9G.007	dibasic processing endopeptidase (unsequenced)	9
U9G.008	leulysin	2
U9G.012	peptidase yscJ	2
U9G.029	prolyl endopeptidase (Spinacia)	3
U9G.033	substance P endopeptidase (of CSF)	3
U9G.053	miniglucagon endopeptidase	1
U9G.054	LPXTGase (Streptococcus pyogenes) and similar	4
U9G.055	D-aspartyl endopeptidase	4
U9G.060	nuclear-scaffold peptidase activity	9
U9G.066	cancer procoagulant	1
U9G.070	salivary glutaminyl endopeptidase	2
U9G.071	transthyretin	5
X42.001	protease I	1
XM02.001	angiotensin-converting enzyme compound peptidase	27
XM12.001	meprin A complex peptidase	71
XM14.001	metallocarboxypeptidase D compound peptidase	2
XP01.001	tricorn peptidase complex	14				R
XS01.001	polyserase-1	1
XS01.002	polyserase-2	4
XS01.004	ovochymase (Xenopus-type)	1
XS26.001	signal peptidase complex (animal)	1886
XS26.002	mitochondrial signal peptidase complex	1
XS68.001	PIDD auto-processing protein	2
XT01.001	20S constitutive proteasome peptidase complex (eukaryote)	950
XT01.002	26S proteasome peptidase complex (eukaryote)	139
XT01.003	20 S immunoproteasome peptidase complex (eukaryote)	352