$VAR1 = undef;

Summary for peptidase S01.228: hepatocyte growth factor activator

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates

 

Names
MEROPS Namehepatocyte growth factor activator
Other nameshepatocyte growth factor activating endopeptidase, HGFA
Domain architecture
MEROPS Classification
Classification Clan PA >> Subclan PA(S) >> Family S1 >> Subfamily A >> S01.228
Holotypehepatocyte growth factor activator (Homo sapiens), Uniprot accession Q04756 (peptidase unit: 408-648), MERNUM MER0000186
History Identifier created: Handbook of Proteolytic Enzymes (1998) Academic Press, London.
Activity
Catalytic typeSerine
NC-IUBMBNot yet included in IUBMB recommendations.
Proteolytic eventsCutDB database (1 cleavage)
Activity statushuman: active (Kitamura, 2004)
mouse: active (by similarity to human)
PhysiologyGenerates active hepatocyte growth factor from precursor.
Other databases TREEFAMhttp://www.treefam.org/family/TF329901
Human genetics
Gene symbol Locus Megabases Ensembl Entrez gene Gene Cards OMIM
HGFAC 4p16 ENSG00000109758 3083 HGFAC 604552
Mouse genetics
Gene symbol Position Megabases Ensembl Entrez gene MGI
Hgfac 5:B2 ENSMUSG00000029102 54426 MGI:1859281