$VAR1 = undef;
Summary for peptidase S01.228: hepatocyte growth factor activator
| Names | |
|---|---|
| MEROPS Name | hepatocyte growth factor activator |
| Other names | hepatocyte growth factor activating endopeptidase, HGFA |
| Domain architecture |
|---|
| MEROPS Classification | |
|---|---|
| Classification | Clan PA >> Subclan PA(S) >> Family S1 >> Subfamily A >> S01.228 |
| Holotype | hepatocyte growth factor activator (Homo sapiens), Uniprot accession Q04756 (peptidase unit: 408-648), MERNUM MER0000186 |
| History | Identifier created: Handbook of Proteolytic Enzymes (1998) Academic Press, London. |
| Activity | |||
|---|---|---|---|
| Catalytic type | Serine | ||
| NC-IUBMB | Not yet included in IUBMB recommendations. | ||
| Proteolytic events | CutDB database (1 cleavage) | ||
| Activity status | human: active (Kitamura, 2004) mouse: active (by similarity to human) | ||
| Physiology | Generates active hepatocyte growth factor from precursor. | ||
| Other databases | TREEFAM | http://www.treefam.org/family/TF329901 | |
| Human genetics | ||||||
|---|---|---|---|---|---|---|
| Gene symbol | Locus | Megabases | Ensembl | Entrez gene | Gene Cards | OMIM |
| HGFAC | 4p16 | ENSG00000109758 | 3083 | HGFAC | 604552 | |
| Mouse genetics | ||||||
| Gene symbol | Position | Megabases | Ensembl | Entrez gene | MGI | |
| Hgfac | 5:B2 | ENSMUSG00000029102 | 54426 | MGI:1859281 | ||
