$VAR1 = undef;

Summary for peptidase M12.310: metallopeptidase MTP-1

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Literature Substrates

 

Names
MEROPS Namemetallopeptidase MTP-1
Other namesmetalloprotease MTP-1 (Ancylostoma caninum)
Domain architecture
MEROPS Classification
Classification Clan MA >> Subclan MA(M) >> Family M12 >> Subfamily A >> M12.310
Holotypemetallopeptidase MTP-1 (Ancylostoma caninum) (peptidase unit: 141-328), MERNUM MER0015241
History Identifier created: MEROPS 6.5 (22 December 2003)
Activity
Catalytic typeMetallo
NC-IUBMBNot yet included in IUBMB recommendations.
Cleavage site specificity Explanations of how to interpret the following cleavage site sequence logo and specificity matrix can be found here.
Cleavage pattern-/vfgl/-/-Scissile bondla/-/-/- (based on 18 cleavages)
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Specificity matrix
 
Amino acid P4 P3 P2 P1 P1' P2' P3' P4'
Gly 1 3 2 1 1 2 2 0
Pro 1 0 0 1 1 2 2 1
Ala 0 0 3 2 4 1 3 2
Val 1 4 4 0 1 3 0 2
Leu 2 3 2 3 7 3 1 1
Ile 1 0 0 0 0 0 0 0
Met 0 0 0 0 0 0 0 0
Phe 0 3 1 0 0 0 0 1
Tyr 1 0 0 0 0 1 0 1
Trp 0 0 0 0 0 1 0 0
Ser 1 0 1 0 2 1 1 1
Thr 1 0 1 0 0 1 2 2
Cys 0 0 0 1 0 0 0 0
Asn 1 1 0 1 1 0 3 2
Gln 1 0 1 0 0 0 1 0
Asp 1 0 1 4 0 2 2 1
Glu 1 0 0 0 0 0 0 1
Lys 2 1 2 2 0 0 0 2
Arg 0 1 0 1 0 0 0 0
His 1 0 0 2 1 1 1 1