$VAR1 = undef;

Summary for peptidase C01.129: cathepsin L3 (Fasciola sp.)

Summary Alignment Sequences Sequence features Distribution Literature Substrates

 

Names
MEROPS Namecathepsin L3 (Fasciola sp.)
Other namesCL3 peptidase (Fasciola hepatica), FgCatL1G
Domain architecture
MEROPS Classification
Classification Clan CA >> Subclan (none) >> Family C1 >> Subfamily A >> C01.129
Holotypecathepsin L3 (Fasciola sp.) (Fasciola hepatica) (peptidase unit: 87-303), MERNUM MER0014557
History Identifier created: MEROPS 8.5 (24 August 2009)
Activity
Catalytic typeCysteine
NC-IUBMBNot yet included in IUBMB recommendations.
Cleavage site specificity Explanations of how to interpret the following cleavage site sequence logo and specificity matrix can be found here.
Cleavage patternp/-/g/-Scissile bond-/g/-/- (based on 72 cleavages)
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Specificity matrix
 
Amino acid P4 P3 P2 P1 P1' P2' P3' P4'
Gly 12 15 22 12 13 24 13 18
Pro 18 13 9 8 10 5 12 8
Ala 10 7 6 4 8 2 4 7
Val 0 3 4 7 2 3 4 3
Leu 1 1 2 5 1 3 4 5
Ile 1 0 2 1 4 2 1 2
Met 2 0 3 0 1 0 2 0
Phe 4 1 1 3 2 1 0 1
Tyr 1 2 1 0 1 4 1 1
Trp 0 0 0 0 1 0 0 2
Ser 1 2 4 3 0 4 1 3
Thr 1 4 3 3 4 1 5 1
Cys 1 0 0 0 1 1 1 2
Asn 0 4 1 1 0 1 6 1
Gln 3 2 5 2 5 1 4 3
Asp 1 4 2 6 2 3 3 5
Glu 3 3 2 4 6 5 1 3
Lys 7 5 0 6 5 3 2 1
Arg 3 4 3 5 3 3 4 3
His 0 1 2 2 0 3 1 0