$VAR1 = undef;

Summary for peptidase C01.072: rhodesain

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates

 

Names
MEROPS Namerhodesain
Other namesbrucipain, trypanopain, major cathepsin L-like cysteine protease (Trypanosoma brucei)
Domain architecture
MEROPS Classification
Classification Clan CA >> Subclan (none) >> Family C1 >> Subfamily A >> C01.072
Holotyperhodesain (Trypanosoma brucei), Uniprot accession P14658 (peptidase unit: 126-340), MERNUM MER0000664
History Identifier created: MEROPS 5.8 (19 March 2002)
Activity
Catalytic typeCysteine
NC-IUBMBNot yet included in IUBMB recommendations.
Pathways KEGGAfrican trypanosomiasis
Cleavage site specificity Explanations of how to interpret the following cleavage site sequence logo and specificity matrix can be found here.
Cleavage pattern-/-/fl/krmScissile bond-/-/-/- (based on 11 cleavages)
weblogo
Specificity matrix
 
Amino acid P4 P3 P2 P1 P1' P2' P3' P4'
Gly 0 1 1 0 0 0 0 1
Pro 0 1 0 0 0 0 0 0
Ala 0 3 0 0 0 0 0 0
Val 0 1 0 0 0 0 0 0
Leu 0 0 3 0 0 1 0 0
Ile 0 0 0 0 0 0 1 0
Met 0 0 0 2 0 0 0 0
Phe 0 0 4 0 0 0 0 0
Tyr 0 0 1 1 0 0 0 0
Trp 0 0 1 0 0 0 0 0
Ser 1 0 0 0 1 0 0 0
Thr 0 0 0 0 0 0 0 0
Cys 0 0 0 0 0 0 0 0
Asn 0 0 0 0 0 0 0 0
Gln 0 0 0 0 0 0 0 0
Asp 0 1 0 0 0 0 0 0
Glu 0 0 0 0 0 0 0 0
Lys 0 1 0 4 0 0 0 0
Arg 0 0 1 4 0 0 0 0
His 0 0 0 0 0 0 0 0