$VAR1 = undef;

Summary for peptidase A01.046: napsin A

Names
MEROPS Name	napsin A
Other names	Asp4 protease, dap1, dap2, decidual aspartyl protease, kidney aspartic protease (Mus musculus), Mername-AA043 peptidase, TA02 protein

Domain architecture

MEROPS Classification
Classification	Clan AA >> Subclan (none) >> Family A1 >> Subfamily A >> A01.046
Holotype	napsin A (Homo sapiens), Uniprot accession O96009 (peptidase unit: 65-394), MERNUM MER0004981
History	Identifier created: MEROPS 3.21 (12 May 1999)

Activity
Catalytic type	Aspartic
Peplist	Included in the Peplist with identifier PL00024
NC-IUBMB	Not yet included in IUBMB recommendations.
Physiology	Abundantly expressed in normal human lung and kidney tissue, and particularly highly expressed in lung adenocarcinomas (Chuman et al., 1999; Hirano et al., 2000).
Pharmaceutical relevance	Napsin A has been described as a useful marker for diagnosis of primary lung adenocarcinoma (Ueno et al., 2003).
Pathways	KEGG	Lysosome
Other databases	WIKIPEDIA	http://en.wikipedia.org/wiki/NAPSA