$VAR1 = undef;

Summary for peptidase M12.025: ADAMTS15 peptidase

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Literature Substrates

 

Names
MEROPS NameADAMTS15 peptidase
Domain architecture
MEROPS Classification
Classification Clan MA >> Subclan MA(M) >> Family M12 >> Subfamily B >> M12.025
HolotypeADAMTS15 peptidase (Homo sapiens), Uniprot accession Q8TE58 (peptidase unit: 213-427), MERNUM MER0017029
History Identifier created: MEROPS 5.9 (21 June 2002)
Activity
Catalytic typeMetallo
NC-IUBMBNot yet included in IUBMB recommendations.
Activity statushuman: putative
mouse: putative
Other databases TREEFAMhttp://www.treefam.org/family/TF331949
Cleavage site specificity Explanations of how to interpret the following cleavage site sequence logo and specificity matrix can be found here.
Cleavage pattern-/-/-/eScissile bonda/-/g/- (based on 125 cleavages)
weblogo
Specificity matrix
 
Amino acid P4 P3 P2 P1 P1' P2' P3' P4'
Gly 10 10 5 11 6 3 39 9
Pro 3 4 2 5 0 3 2 8
Ala 13 15 28 17 38 16 21 16
Val 8 16 7 3 16 17 8 10
Leu 20 14 17 0 17 15 4 11
Ile 7 9 7 2 5 15 4 11
Met 6 3 7 6 1 4 2 1
Phe 0 11 4 4 3 5 2 3
Tyr 1 9 0 6 6 6 2 3
Trp 1 0 0 0 0 0 0 3
Ser 8 5 5 7 7 4 3 8
Thr 8 8 5 3 3 8 4 7
Cys 0 0 4 0 0 2 0 2
Asn 3 3 4 2 4 5 3 3
Gln 5 3 14 9 8 5 6 8
Asp 6 4 7 2 2 1 4 6
Glu 5 6 4 45 4 4 12 10
Lys 6 3 2 0 0 1 1 0
Arg 10 1 2 0 3 10 5 3
His 5 1 1 3 2 1 3 3
Human genetics
Gene symbol Locus Megabases Ensembl Entrez gene Gene Cards OMIM
ADAMTS15 11q25 ENSG00000166106 170689 ADAMTS15 607509
Mouse genetics
Gene symbol Position Megabases Ensembl Entrez gene MGI
Adamts15 9:A4 ENSMUSG00000033453 235130 MGI:2449569