Summary for peptidase M27.001: tentoxilysin

Summary Alignment Sequences Sequence features Distribution Structure Literature Substrates Inhibitors Pharma


MEROPS Nametentoxilysin
Other namesTeNT, tetanus neurotoxin, tetanus toxin
Domain architecture
MEROPS Classification
Classification Clan MA >> Subclan MA(E) >> Family M27 >> Subfamily (none) >> M27.001
Holotypetentoxilysin (Clostridium tetani), Uniprot accession P04958 (peptidase unit: 117-457), MERNUM MER0001174
History Identifier created: Handbook of Proteolytic Enzymes (1998) Academic Press, London.
Catalytic typeMetallo
PeplistIncluded in the Peplist with identifier PL00243
NC-IUBMBSubclass 3.4 (Peptidases) >> Sub-subclass 3.4.24 (Metalloendopeptidases) >> Peptidase
EnzymologyBRENDA database
Proteolytic eventsCutDB database (1 cleavage)
Pharmaceutical relevanceActivity essential for action of tetanus toxin.