$VAR1 = undef;

Summary for peptidase S08.051: aqualysin 1

Names
MEROPS Name	aqualysin 1
Other names	caldolysin (Thermus aquaticus strain T351), protease PA720 (Streptomyces rutgersensis)

Domain architecture

MEROPS Classification
Classification	Clan SB >> Subclan (none) >> Family S8 >> Subfamily A >> S08.051
Holotype	aqualysin 1 (Thermus aquaticus), Uniprot accession P08594 (peptidase unit: 128-453), MERNUM MER0000325
History	Identifier created: Handbook of Proteolytic Enzymes (1998) Academic Press, London.

Activity
Catalytic type	Serine
Peplist	Included in the Peplist with identifier PL00351
NC-IUBMB	Subclass 3.4 (Peptidases) >> Sub-subclass 3.4.21 (Serine endopeptidases) >> Peptidase 3.4.21.111
Enzymology	BRENDA database
Proteolytic events	CutDB database (9 cleavages)
Cleavage site specificity	Explanations of how to interpret the following cleavage site sequence logo and specificity matrix can be found here.
Cleavage pattern	-/-/-/--/l/-/- (based on 11 cleavages)

Specificity matrix

Amino acid	P4	P3	P2	P1	P1'	P2'	P3'	P4'
Gly	0	1	2	0	1	1	0	3
Pro	0	0	2	0	0	0	1	1
Ala	1	2	1	0	2	0	0	0
Val	1	1	2	0	0	1	2	0
Leu	1	2	1	2	1	4	0	1
Ile	0	0	0	0	0	0	0	0
Met	0	0	0	0	0	0	0	0
Phe	1	0	1	3	1	0	0	0
Tyr	2	0	0	1	2	1	1	0
Trp	0	0	0	0	0	0	0	0
Ser	0	0	0	1	0	0	1	0
Thr	0	1	0	0	0	1	1	0
Cys	0	0	0	0	0	0	0	0
Asn	1	0	1	0	0	0	0	0
Gln	0	1	0	1	0	0	0	0
Asp	0	0	0	0	0	0	0	0
Glu	2	1	0	1	0	1	0	1
Lys	0	0	0	1	0	0	0	1
Arg	1	1	0	0	0	0	1	0
His	1	0	1	0	2	0	0	1