Summary for peptidase M14.010: carboxypeptidase A3

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Literature Substrates Inhibitors Pharma


MEROPS Namecarboxypeptidase A3
Other namesmast cell carboxypeptidase A, tissue carboxypeptidase A
Domain architecture
MEROPS Classification
Classification Clan MC >> Subclan (none) >> Family M14 >> Subfamily A >> M14.010
Holotypecarboxypeptidase A3 (Rattus norvegicus), Uniprot accession P21961 (peptidase unit: 108-417), MERNUM MER0001189
History Identifier created: Handbook of Proteolytic Enzymes (1998) Academic Press, London.
Catalytic typeMetallo
PeplistIncluded in the Peplist with identifier PL00214
NC-IUBMBNot yet included in IUBMB recommendations.
Proteolytic eventsCutDB database (1 cleavage)
Activity statushuman: active (Springman, 2004)
mouse: active (Reynolds et al., 1989)
Pathways KEGGPancreatic secretion
KEGGProtein digestion and absorption
KEGGRenin-angiotensin system
Other databases TREEFAM
Human genetics
Gene symbol Locus Megabases Ensembl Entrez gene Gene Cards OMIM
CPA3 3q21-q25 ENSG00000163751 1359 CPA3 114851
Mouse genetics
Gene symbol Position Megabases Ensembl Entrez gene MGI
Cpa3 3:A2 ENSMUSG00000001865 12873 MGI:88479