$VAR1 = undef;

Summary for peptidase C01.142: cathepsin L2 (Fasciola sp.)

Summary Alignment Sequences Sequence features Distribution Literature Substrates

 

Names
MEROPS Namecathepsin L2 (Fasciola sp.)
Other namesCL2, FhCatL2, FhCatL5, FheCL2
Domain architecture
MEROPS Classification
Classification Clan CA >> Subclan (none) >> Family C1 >> Subfamily A >> C01.142
Holotypecathepsin L2 (Fasciola sp.) (Fasciola hepatica) (peptidase unit: 107-323), MERNUM MER0002302
History Identifier created: MEROPS 8.2 (4 August 2008)
Activity
Catalytic typeCysteine
NC-IUBMBNot yet included in IUBMB recommendations.
Cleavage site specificity Explanations of how to interpret the following cleavage site sequence logo and specificity matrix can be found here.
Cleavage pattern-/-/-/-Scissile bond-/gp/-/- (based on 54 cleavages)
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Specificity matrix
 
Amino acid P4 P3 P2 P1 P1' P2' P3' P4'
Gly 9 11 13 9 9 14 9 12
Pro 7 4 7 8 3 11 9 7
Ala 8 8 2 1 4 0 5 5
Val 2 2 2 1 4 1 3 2
Leu 2 4 7 4 4 1 3 1
Ile 5 1 3 4 2 2 1 0
Met 1 0 0 2 1 0 0 0
Phe 0 1 1 2 1 2 1 1
Tyr 1 0 1 1 1 1 2 0
Trp 0 0 0 1 0 1 0 0
Ser 2 3 2 1 5 4 4 2
Thr 0 3 5 0 3 0 1 2
Cys 0 0 0 0 0 1 0 1
Asn 2 2 3 2 1 1 0 5
Gln 2 4 2 3 2 2 2 3
Asp 1 1 2 3 5 1 0 1
Glu 3 2 0 4 2 3 4 3
Lys 3 3 2 3 2 3 4 4
Arg 3 2 2 3 1 3 2 1
His 0 1 0 1 1 0 1 1