$VAR1 = undef;

Summary for peptidase C19.010: ubiquitin-specific peptidase 4

Names
MEROPS Name	ubiquitin-specific peptidase 4
Other names	ubiquitin-specific protease 4, Unp oncoprotein (Mus musculus, UNP g.p. (Mus musculus), Unph protein (Homo sapiens), USP4 g.p. (Homo sapiens), USP4

Domain architecture

MEROPS Classification
Classification	Clan CA >> Subclan (none) >> Family C19 >> Subfamily (none) >> C19.010
Holotype	ubiquitin-specific peptidase 4 (Homo sapiens), Uniprot accession Q13107 (peptidase unit: 264-934), MERNUM MER0001795
History	Identifier created: MEROPS 3.03 (10 September 1998)

Activity
Catalytic type	Cysteine
NC-IUBMB	Not yet included in IUBMB recommendations.
Activity status	human: active (Gilchrist & Baker, 2000) mouse: active (Gilchrist & Baker, 2000)
Other databases	TREEFAM	http://www.treefam.org/family/TF106276
Cleavage site specificity	Explanations of how to interpret the following cleavage site sequence logo and specificity matrix can be found here.
Cleavage pattern	L/R/G/G-/-/-/- (based on 12 cleavages)

Specificity matrix

Amino acid	P4	P3	P2	P1	P1'	P2'	P3'	P4'
Gly	0	0	12	12	1	0	1	0
Pro	0	0	0	0	1	1	1	3
Ala	0	0	0	0	0	0	0	0
Val	0	0	0	0	0	0	0	0
Leu	12	0	0	0	0	0	0	0
Ile	0	0	0	0	3	3	1	0
Met	0	0	0	0	2	0	0	0
Phe	0	0	0	0	0	0	0	1
Tyr	0	0	0	0	0	0	0	1
Trp	0	0	0	0	0	0	0	0
Ser	0	0	0	0	0	0	0	1
Thr	0	0	0	0	0	0	0	0
Cys	0	0	0	0	0	0	0	0
Asn	0	0	0	0	0	0	0	0
Gln	0	0	0	0	0	1	0	0
Asp	0	0	0	0	0	0	0	0
Glu	0	0	0	0	0	0	3	0
Lys	0	0	0	0	1	1	1	0
Arg	0	12	0	0	1	0	0	1
His	0	0	0	0	0	1	0	0