$VAR1 = undef;

Summary for peptidase M12.226: ADAMTS8 peptidase

Names
MEROPS Name	ADAMTS8 peptidase
Other names	ADAMTS8 g.p. (Homo sapiens), METH-2

Domain architecture

MEROPS Classification
Classification	Clan MA >> Subclan MA(M) >> Family M12 >> Subfamily B >> M12.226
Holotype	ADAMTS8 peptidase (Homo sapiens), Uniprot accession Q9UP79 (peptidase unit: 214-429), MERNUM MER0005545
History	Identifier created: MEROPS 3.4 (5 November 1999)

Activity
Catalytic type	Metallo
NC-IUBMB	Not yet included in IUBMB recommendations.
Activity status	human: putative mouse: putative
Other databases	WIKIPEDIA	http://en.wikipedia.org/wiki/ADAMTS8
Cleavage site specificity	Explanations of how to interpret the following cleavage site sequence logo and specificity matrix can be found here.
Cleavage pattern	s/-/q/-ls/l/-/- (based on 10 cleavages)

Specificity matrix

Amino acid	P4	P3	P2	P1	P1'	P2'	P3'	P4'
Gly	0	1	1	0	0	0	1	1
Pro	0	0	0	0	0	0	0	2
Ala	0	0	0	1	1	0	1	2
Val	0	1	1	0	0	0	1	1
Leu	1	0	2	1	5	3	1	0
Ile	0	0	0	0	0	0	0	0
Met	0	1	0	1	0	0	0	0
Phe	0	1	0	0	0	0	0	0
Tyr	0	1	0	1	0	0	0	1
Trp	0	0	0	0	0	0	0	0
Ser	3	0	1	1	2	1	2	1
Thr	2	1	0	0	0	1	2	0
Cys	0	0	0	0	0	0	0	0
Asn	1	0	0	1	0	0	1	0
Gln	1	1	4	2	1	1	0	0
Asp	2	0	0	1	1	0	0	0
Glu	0	1	0	1	0	0	1	0
Lys	0	1	1	0	0	2	0	1
Arg	0	0	0	0	0	2	0	1
His	0	1	0	0	0	0	0	0