$VAR1 = undef;
Summary for peptidase A02.008: murine leukemia virus-type retropepsin
Names | |
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MEROPS Name | murine leukemia virus-type retropepsin |
Other names | Moloney murine leukemia virus-type retropepsin, retropepsin (Moloney murine leukemia virus), xenotropic murine leukemia virus-related virus (XMRV) retropepsin |
Domain architecture |
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MEROPS Classification | |
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Classification | Clan AA >> Subclan (none) >> Family A2 >> Subfamily A >> A02.008 |
Holotype | murine leukemia virus-type retropepsin (Moloney murine leukemia virus), Uniprot accession P03355 (peptidase unit: 535-659), MERNUM MER0001480 |
History | Identifier created: Handbook of Proteolytic Enzymes (1998) Academic Press, London. |
Activity | |||
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Catalytic type | Aspartic | ||
Peplist | Included in the Peplist with identifier PL00030 | ||
NC-IUBMB | Not yet included in IUBMB recommendations. | ||
Proteolytic events | CutDB database (5 cleavages) | ||
Physiology | Processing of viral polyprotein. | ||
Cleavage site specificity | Explanations of how to interpret the following cleavage site sequence logo and specificity matrix can be found here. | ||
Cleavage pattern | S/q/N/YlftP/Il/V/Q (based on 20 cleavages) |
Specificity matrix | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Mouse genetics | ||||||
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Gene symbol | Position | Megabases | Ensembl | Entrez gene | MGI | |
Mela | 8 E1 | ENSMUSG00000074036 | 17276 | MGI:107565 |