$VAR1 = undef;
Summary for peptidase C15.001: pyroglutamyl-peptidase I (prokaryote)
| Names | |
|---|---|
| MEROPS Name | pyroglutamyl-peptidase I (prokaryote) |
| Other names | 5-oxoprolyl-peptidase, pyrase, PGP-1, pyroglutamyl aminopeptidase, pyrrolidone carboxyl peptidase, pyrrolidone-carboxylate peptidase |
| Domain architecture |
|---|
| MEROPS Classification | |
|---|---|
| Classification | Clan CF >> Subclan (none) >> Family C15 >> Subfamily (none) >> C15.001 |
| Holotype | pyroglutamyl-peptidase I (prokaryote) (Bacillus amyloliquefaciens), Uniprot accession P46107 (peptidase unit: 1-215), MERNUM MER0001424 |
| History | Identifier created: Handbook of Proteolytic Enzymes (1998) Academic Press, London. |
| Activity | |||
|---|---|---|---|
| Catalytic type | Cysteine | ||
| Peplist | Included in the Peplist with identifier PL00105 | ||
| NC-IUBMB | Subclass 3.4 (Peptidases) >> Sub-subclass 3.4.19 (Omega peptidases) >> Peptidase 3.4.19.3 | ||
| Enzymology | BRENDA database | ||
| Biotechnology | Removal of pyroglutamyl groups from peptides, in protein sequencing. Laboratory use in identification of group A streptococci and enterococci. | ||
| Physiology | Removal of pyroglutamyl groups from peptides in protein catabolism. | ||
| Other databases | PANTHER | http://www.pantherdb.org/panther/familyList.do?searchType=basic&fieldName=all&listType=6&fieldValue=PTHR23402:SF1 | |
