$VAR1 = undef;

Summary for peptidase S01.072: matriptase-3

Names
MEROPS Name	matriptase-3
Other names	Tryp_SPc peptidase

Domain architecture

MEROPS Classification
Classification	Clan PA >> Subclan PA(S) >> Family S1 >> Subfamily A >> S01.072
Holotype	matriptase-3 (Mus musculus), Uniprot accession Q8BIK6 (peptidase unit: 529-822), MERNUM MER0028239
History	Identifier created: MEROPS 6.3 (23 June 2003)

Activity
Catalytic type	Serine
NC-IUBMB	Not yet included in IUBMB recommendations.
Proteolytic events	CutDB database (4 cleavages)
Activity status	human: putative mouse: putative
Other databases	TREEFAM	http://www.treefam.org/family/TF330647
Cleavage site specificity	Explanations of how to interpret the following cleavage site sequence logo and specificity matrix can be found here.
Cleavage pattern	-/-/-/Rk/-/-/- (based on 114 cleavages)

Specificity matrix

Amino acid	P4	P3	P2	P1	P1'	P2'	P3'	P4'
Gly	7	1	15	3	15	15	23	7
Pro	12	6	20	3	0	4	9	9
Ala	5	14	22	4	14	22	10	17
Val	11	5	12	2	3	7	7	13
Leu	2	4	3	1	3	8	11	16
Ile	8	3	2	0	2	3	2	5
Met	1	2	1	3	2	0	1	0
Phe	5	3	1	0	0	1	3	2
Tyr	1	1	1	0	0	0	1	1
Trp	0	0	0	0	2	0	2	0
Ser	7	7	6	2	16	13	5	5
Thr	2	15	6	3	4	6	9	5
Cys	2	0	2	1	0	1	1	2
Asn	2	3	2	1	1	7	2	2
Gln	5	1	5	3	2	5	7	5
Asp	1	7	1	0	2	1	3	11
Glu	2	7	5	1	0	6	5	3
Lys	3	5	1	3	28	3	5	7
Arg	8	10	3	82	12	5	5	2
His	0	0	0	2	6	5	1	0