$VAR1 = undef;

Summary for XT01.002

Summary Substrates

 

Names
MEROPS Name26S proteasome peptidase complex (eukaryote)
MEROPS Classification
Activity
Catalytic typeThreonine
NC-IUBMBNot yet included in IUBMB recommendations.
Cleavage site specificity Explanations of how to interpret the following cleavage site sequence logo and specificity matrix can be found here.
Cleavage pattern-/-/-/-Scissile bond-/-/-/- (based on 139 cleavages)
weblogo
Specificity matrix
 
Amino acid P4 P3 P2 P1 P1' P2' P3' P4'
Gly 9 5 6 7 10 7 10 11
Pro 26 19 9 8 20 17 21 20
Ala 6 4 6 4 5 6 4 4
Val 12 12 14 7 6 13 15 13
Leu 17 18 15 27 13 16 17 18
Ile 2 1 2 2 2 5 3 2
Met 1 0 1 3 4 2 1 3
Phe 6 6 4 6 5 9 8 6
Tyr 1 4 4 4 3 2 3 3
Trp 2 2 2 3 3 1 1 1
Ser 14 10 15 12 18 13 14 8
Thr 6 7 9 9 6 4 7 4
Cys 3 3 3 2 1 1 2 4
Asn 3 5 4 1 4 4 2 2
Gln 5 9 12 12 10 9 5 8
Asp 0 4 2 7 4 5 4 6
Glu 11 8 10 9 8 8 9 8
Lys 3 8 6 3 4 5 3 7
Arg 8 13 10 11 10 8 7 9
His 2 0 4 2 3 3 2 0