Summary for peptidase S60.001: lactoferrin

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Inhibitors Pharma

 

Names
MEROPS Namelactoferrin
Domain architecture
MEROPS Classification
Classification Clan SR >> Subclan (none) >> Family S60 >> Subfamily (none) >> S60.001
Holotypelactoferrin (Homo sapiens), Uniprot accession P02788 (peptidase unit: 20-357), MERNUM MER0020365
History Identifier created: MEROPS 6.3 (23 June 2003)
Activity
Catalytic typeSerine
NC-IUBMBNot yet included in IUBMB recommendations.
Proteolytic eventsCutDB database (6 cleavages)
Activity statushuman: active (Hendrixson et al., 2003)
mouse: active (by similarity to human)
Other databases PANTHERhttp://www.pantherdb.org/panther/familyList.do?searchType=basic&fieldName=all&listType=6&fieldValue=PTHR11485:SF33
Human genetics
Gene symbol Locus Megabases Ensembl Entrez gene Gene Cards OMIM
LTF 3q21-q23 ENSG00000012223 4057 LTF 150210
Mouse genetics
Gene symbol Position Megabases Ensembl Entrez gene MGI
Ltf 9:F3 ENSMUSG00000032496 17002 MGI:96837