$VAR1 = undef;

Summary for peptidase S26.016: SpsB signal peptidase

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates

 

Names
MEROPS NameSpsB signal peptidase
Other namesSip2 (Staphylococcus sp.), Sip3 (Staphylococcus sp.)
Domain architecture
MEROPS Classification
Classification Clan SF >> Subclan (none) >> Family S26 >> Subfamily A >> S26.016
HolotypeSpsB signal peptidase (Staphylococcus aureus), Uniprot accession P0A069 (peptidase unit: 23-184), MERNUM MER0003273
History Identifier created: MEROPS 6.4 (24 September 2003)
Activity
Catalytic typeSerine
NC-IUBMBNot yet included in IUBMB recommendations.
Cleavage site specificity Explanations of how to interpret the following cleavage site sequence logo and specificity matrix can be found here.
Cleavage patternt/A/k/AScissile bondAes/se/k/i (based on 49 cleavages)
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Specificity matrix
 
Amino acid P4 P3 P2 P1 P1' P2' P3' P4'
Gly 2 0 1 1 1 0 3 2
Pro 1 0 0 0 0 1 0 6
Ala 1 34 2 46 22 2 1 3
Val 1 6 0 0 2 2 4 4
Leu 1 2 6 0 0 1 1 0
Ile 4 0 0 0 1 2 0 13
Met 0 0 0 0 1 0 0 0
Phe 0 0 1 0 1 0 1 1
Tyr 0 0 0 0 0 0 1 0
Trp 0 0 0 0 0 0 0 0
Ser 4 4 3 0 5 17 5 3
Thr 14 1 0 0 0 4 4 2
Cys 0 0 0 0 0 0 0 0
Asn 5 0 4 1 1 4 5 4
Gln 7 0 2 0 0 1 3 2
Asp 0 0 2 0 1 2 1 4
Glu 4 1 1 0 11 11 2 1
Lys 3 0 18 1 3 2 15 4
Arg 0 0 3 0 0 0 1 0
His 1 0 5 0 0 0 2 0