$VAR1 = undef;

Summary for peptidase C13.007: legumain, trematode-type

Summary Alignment Tree Sequences Sequence features Distribution Literature Substrates

 

Names
MEROPS Namelegumain, trematode-type
Other nameshemoglobinase, Sm32 (Schistosoma mansoni), Sj32 (Schistosoma japonica)
Domain architecture
MEROPS Classification
Classification Clan CD >> Subclan (none) >> Family C13 >> Subfamily (none) >> C13.007
Holotypelegumain, trematode-type (Schistosoma japonicum), Uniprot accession P42665 (peptidase unit: 27-285), MERNUM MER0000843
History Identifier created: MEROPS 8.1 (5 May 2008)
Activity
Catalytic typeCysteine
NC-IUBMBSubclass 3.4 (Peptidases) >> Sub-subclass 3.4.22 (Cysteine endopeptidases) >> Peptidase 3.4.22.34
EnzymologyBRENDA database
Cleavage site specificity Explanation of how to interpret specificity from combinatorial substrates can be found here.
Specificity from combinatorial peptides
 
Organism comment P4 P3 P2 P1 P1' P2' P3' P4' optimal substrate fluorophore or acceptor-donor pair Reference
Schistosoma mansoni recombinant nd A/T/S A/T/P N - - - - AAN AMC Mathieu et al., 2002
Schistosoma mansoni recombinant nd T/A/S A/T/S N - - - - TAN AMC Mathieu et al., 2002