$VAR1 = undef;

Summary for peptidase A01.031: yapsin-2

Names
MEROPS Name	yapsin-2
Other names	MKC7 g.p. [obs.] (Saccharomyces cerevisiae), YPS2 g.p. (Saccharomyces cerevisiae)

Domain architecture

MEROPS Classification
Classification	Clan AA >> Subclan (none) >> Family A1 >> Subfamily A >> A01.031
Holotype	yapsin-2 (Saccharomyces cerevisiae), Uniprot accession P53379 (peptidase unit: 61-471), MERNUM MER0002653
History	Identifier created: Handbook of Proteolytic Enzymes (1998) Academic Press, London.

Activity
Catalytic type	Aspartic
Peplist	Included in the Peplist with identifier PL00021
NC-IUBMB	Not yet included in IUBMB recommendations.
Physiology	Contributes to processing of protein precursors in Saccharomyces cerevisiae.
Other databases	PANTHER	http://www.pantherdb.org/panther/familyList.do?searchType=basic&fieldName=all&listType=6&fieldValue=PTHR13683:SF412
Cleavage site specificity	Explanations of how to interpret the following cleavage site sequence logo and specificity matrix can be found here.
Cleavage pattern	-/Ye/krv/RKE/A/E/A (based on 16 cleavages)

Specificity matrix

Amino acid	P4	P3	P2	P1	P1'	P2'	P3'	P4'
Gly	0	0	0	0	0	0	0	0
Pro	0	0	0	0	0	0	0	0
Ala	0	0	0	0	0	13	2	13
Val	0	0	2	0	0	1	0	0
Leu	1	0	0	0	2	0	0	0
Ile	0	0	0	0	0	0	0	0
Met	1	0	0	0	1	0	0	0
Phe	0	0	1	0	0	0	1	0
Tyr	0	10	0	0	0	0	0	0
Trp	0	0	0	0	0	0	0	0
Ser	0	0	0	0	0	0	0	0
Thr	0	0	0	0	0	0	0	0
Cys	0	0	0	0	0	0	0	0
Asn	0	0	0	0	0	0	0	0
Gln	0	0	1	0	0	0	0	0
Asp	0	1	0	0	0	2	0	0
Glu	0	3	1	0	13	0	13	2
Lys	0	1	7	5	0	0	0	0
Arg	0	0	2	10	0	0	0	0
His	1	1	0	0	0	0	0	0