$VAR1 = undef;

Summary for peptidase C01.013: cathepsin X

Names
MEROPS Name	cathepsin X
Other names	carboxypeptidase LB, cathepsin IV, cathepsin B2, cathepsin P [obs.], cathepsin Y, cathepsin Z [obs.], cathepsin Z1 (Toxocara), CTSZ g.p. (Homo sapiens), cysteine-type carboxypeptidase, lysosomal carboxypeptidase B

Domain architecture

MEROPS Classification
Classification	Clan CA >> Subclan (none) >> Family C1 >> Subfamily A >> C01.013
Holotype	cathepsin X (Homo sapiens), Uniprot accession Q9UBR2 (peptidase unit: 57-302), MERNUM MER0004508
History	Identifier created: MEROPS 3.03 (10 September 1998)

Activity
Catalytic type	Cysteine
Peplist	Included in the Peplist with identifier PL00055
NC-IUBMB	Subclass 3.4 (Peptidases) >> Sub-subclass 3.4.18 (Cysteine-type carboxypeptidases) >> Peptidase 3.4.18.1
Enzymology	BRENDA database
Proteolytic events	CutDB database (4 cleavages)
Activity status	human: active (Menard & Sulea, 2004) mouse: active (by similarity)
Pathways	KEGG	Lysosome
Other databases	WIKIPEDIA	http://en.wikipedia.org/wiki/Cathepsin_Z
Cleavage site specificity	Explanations of how to interpret the following cleavage site sequence logo and specificity matrix can be found here.
Cleavage pattern	-/-/-/--/-/-/- (based on 46 cleavages)

Specificity matrix

Amino acid	P4	P3	P2	P1	P1'
Gly	0	0	0	8	2
Pro	2	4	4	0	1
Ala	0	2	3	4	4
Val	1	1	1	1	1
Leu	4	4	7	6	6
Ile	2	1	1	1	1
Met	1	1	1	1	2
Phe	0	1	4	2	3
Tyr	1	1	1	1	2
Trp	2	2	2	2	1
Ser	0	0	2	2	3
Thr	0	0	0	0	0
Cys	0	0	0	0	0
Asn	3	3	0	2	2
Gln	1	1	1	1	1
Asp	1	1	0	0	1
Glu	3	3	2	6	4
Lys	5	5	5	4	5
Arg	2	0	1	4	3
His	0	0	0	0	0