Summary for peptidase S01.494: Htra2 peptidase (Mycobacterium-type)

Summary Alignment Tree Sequences Sequence features Distribution Literature Substrates

 

Names
MEROPS NameHtra2 peptidase (Mycobacterium-type)
Other namesPepD (Mycobacterium-type)
Domain architecture
MEROPS Classification
Classification Clan PA >> Subclan PA(S) >> Family S1 >> Subfamily C >> S01.494
HolotypeHtra2 peptidase (Mycobacterium-type) (Mycobacterium tuberculosis) (peptidase unit: 180-450), MERNUM MER0004673
History Identifier created: MEROPS 8.2 (4 August 2008)
Activity
Catalytic typeSerine
NC-IUBMBNot yet included in IUBMB recommendations.
Pathways KEGGTwo-component system
Other databases PANTHERhttp://www.pantherdb.org/panther/familyList.do?searchType=basic&fieldName=all&listType=6&fieldValue=PTHR43019:SF14
Cleavage site specificity Explanations of how to interpret the following cleavage site sequence logo and specificity matrix can be found here.
Cleavage pattern-/-/-/VaitScissile bond-/-/-/- (based on 39 cleavages)
weblogo
Specificity matrix
 
Amino acid P4 P3 P2 P1 P1' P2' P3' P4'
Gly 5 1 4 0 2 3 6 4
Pro 2 1 6 0 0 0 0 3
Ala 7 3 4 8 6 5 4 5
Val 5 5 6 18 6 7 2 3
Leu 2 4 1 1 2 7 2 4
Ile 2 3 2 5 0 1 3 1
Met 1 0 0 0 0 0 1 0
Phe 1 1 2 0 1 2 1 1
Tyr 0 0 0 0 0 0 0 0
Trp 0 0 0 0 0 0 0 0
Ser 3 2 2 3 5 4 2 2
Thr 5 7 4 4 5 3 5 1
Cys 0 0 0 0 0 0 0 0
Asn 2 0 1 0 1 2 0 2
Gln 0 2 4 0 2 1 2 1
Asp 2 1 0 0 4 1 4 5
Glu 1 3 1 0 2 0 1 0
Lys 1 3 0 0 1 1 3 6
Arg 0 3 1 0 2 2 3 1
His 0 0 1 0 0 0 0 0