Summary for peptidase S01.176: batroxobin

Summary Alignment Sequences Sequence features Distribution Literature Substrates Inhibitors

 

Names
MEROPS Namebatroxobin
Other namesDefibrase, leucurobin (Bothrops leucurus), Reptilase
Domain architecture
MEROPS Classification
Classification Clan PA >> Subclan PA(S) >> Family S1 >> Subfamily A >> S01.176
Holotypebatroxobin (Bothrops atrox), Uniprot accession P04971 (peptidase unit: 25-249), MERNUM MER0000153
History Identifier created: Handbook of Proteolytic Enzymes (1998) Academic Press, London.
Activity
Catalytic typeSerine
NC-IUBMBNot yet included in IUBMB recommendations.
Proteolytic eventsCutDB database (1 cleavage)
PhysiologyContributes coagulant activity to toxicity of snake venoms.
Pharmaceutical relevanceUsed as benign defibrinating agent.
Other databases WIKIPEDIAhttp://en.wikipedia.org/wiki/Batroxobin
Relevant inhibitors NPGB, PPACK