Statistics for the MEROPS Database
Counts are for peptidases and their homologues, and sequences of the same, that are included in MEROPS.
Contents
- Totals for all catalytic types
- Aspartic peptidases
- Cysteine peptidases
- Glutamic peptidases
- Metallopeptidases
- Asparagine peptidases
- Serine peptidases
- Threonine peptidases
- Peptidases of unknown catalytic type
- Unclassifiable peptidases
| TOTALS FOR ALL CATALYTIC TYPES | ||||||
|---|---|---|---|---|---|---|
| Catalytic Type | Sequences | Identifiers | Identifiers with EC numbers | Identifiers with PDB entries | ||
| Aspartic | 67801 | 324 | 52 | 72 | ||
| Cysteine | 195594 | 1059 | 182 | 280 | ||
| Glutamic | 11410 | 22 | 8 | 5 | ||
| Metallo | 390108 | 1098 | 216 | 352 | ||
| Asparagine | 3817 | 24 | 13 | 24 | ||
| Mixed | 6573 | 54 | 3 | 9 | ||
| Serine | 421584 | 1728 | 188 | 404 | ||
| Threonine | 39415 | 105 | 15 | 51 | ||
| Unknown | 6483 | 14 | 8 | 9 | ||
| Unclassifiable | 3 | 3 | 24 | - | ||
| Grand Total | 1142788 | 4431 | 709 | 1206 | ||
| Total Families | 281 | |||||
| Total clans | 66 | |||||
| Aspartic Peptidases | ||||||
| Clan | Family | Example | Sequences | Identifiers | Identifiers with EC numbers | Identifiers with PDB entries |
| AA | A1 | 20416 | 185 | 25 | 38 | |
| AA | A2 | HIV-1 retropepsin | 1692 | 52 | 4 | 15 |
| AA | A3 | cauliflower mosaic virus-type peptidase | 77 | 6 | 1 | - |
| AA | A9 | spumapepsin | 28 | 1 | 1 | 1 |
| AA | A11 | Copia transposon peptidase | 3791 | 6 | 1 | - |
| AA | A28 | DNA-damage inducible protein 1 | 2918 | 14 | 1 | 4 |
| AA | A32 | PerP peptidase (Caulobacter sp.) | 625 | 2 | 1 | 1 |
| AC | A8 | signal peptidase II | 8864 | 1 | 2 | 1 |
| AD | A22 | presenilin 1 | 3642 | 31 | 1 | 3 |
| AD | A24 | type 4 prepilin peptidase 1 | 8309 | 8 | 3 | 1 |
| AE | A25 | gpr peptidase | 1201 | 1 | 2 | 1 |
| AE | A31 | HybD peptidase | 2031 | 8 | 2 | 5 |
| AF | A26 | omptin | 449 | 5 | 3 | 2 |
| unassigned | A5 | thermopsin | 164 | 1 | 2 | - |
| unassigned | A36 | sporulation factor SpoIIGA | 1241 | 1 | 1 | - |
| unassigned | A37 | sso1175 g.p. (Sulfolobus solfataricus) | 50 | 1 | 1 | - |
| unassigned | A39 | TseI g.p. (Aeromonas dhakensis) | 12303 | 1 | 1 | - |
| Cysteine Peptidases | ||||||
| Clan | Family | Example | Sequences | Identifiers | Identifiers with EC numbers | Identifiers with PDB entries |
| CA | C1 | papain | 21368 | 232 | 26 | 44 |
| CA | C2 | calpain-2 | 6274 | 39 | 4 | 7 |
| CA | C6 | family S30 unassigned peptidases | 410 | 2 | 2 | 1 |
| CA | C10 | streptopain | 1018 | 4 | 2 | 2 |
| CA | C12 | ubiquitinyl hydrolase-L1 | 5233 | 21 | 2 | 5 |
| CA | C16 | murine hepatitis coronavirus papain-like peptidase 1 | 99 | 11 | 1 | 3 |
| CA | C19 | ubiquitin-specific peptidase 14 | 24499 | 201 | 2 | 25 |
| CA | C21 | tymovirus peptidase | 50 | 1 | 1 | 1 |
| CA | C28 | foot-and-mouth disease virus L-peptidase | 29 | 2 | 2 | 1 |
| CA | C31 | family S32 unassigned peptidases | 19 | 1 | 1 | 1 |
| CA | C32 | porcine reproductive and respiratory syndrome virus nsp4 peptidase | 29 | 3 | 1 | 1 |
| CA | C33 | equine arteritis virus Nsp2-type cysteine peptidase | 14 | 1 | 1 | 1 |
| CA | C39 | bacteriocin-processing peptidase | 3574 | 8 | 1 | 1 |
| CA | C47 | staphopain A | 27 | 4 | 2 | 2 |
| CA | C51 | D-alanyl-glycyl peptidase (staphylococcal phage phi11-type) | 205 | 3 | 1 | 1 |
| CA | C54 | autophagin-1 | 1761 | 18 | 1 | 2 |
| CA | C58 | YopT peptidase | 50 | 6 | 1 | 2 |
| CA | C64 | Cezanne peptidase | 1313 | 6 | 1 | 5 |
| CA | C65 | otubain-1 | 1171 | 4 | 1 | 3 |
| CA | C66 | IdeS peptidase | 60 | 3 | 1 | 1 |
| CA | C67 | CylD peptidase | 512 | 4 | 1 | 2 |
| CA | C70 | AvrRpt2 peptidase | 9 | 1 | 1 | - |
| CA | C71 | pseudomurein endoisopeptidase Pei | 2 | 1 | 1 | - |
| CA | C76 | viral tegument protein deubiquitinylating peptidase | 40 | 1 | 1 | 1 |
| CA | C78 | UfSP1 peptidase | 897 | 8 | 1 | 3 |
| CA | C83 | gamma-glutamylcysteine dipeptidyltranspeptidase | 601 | 5 | 1 | 1 |
| CA | C85 | OTUD5 peptidase (Homo sapiens) | 3516 | 18 | 1 | 5 |
| CA | C86 | ataxin-3 | 1190 | 10 | 1 | 2 |
| CA | C87 | nairovirus deubiquitinylating peptidase | 15 | 1 | 1 | 1 |
| CA | C93 | LapG peptidase (Pseudomonas fluorescens) | 283 | 1 | 1 | 2 |
| CA | C96 | McjB peptidase | 166 | 1 | 1 | - |
| CA | C98 | USPL1 peptidase | 203 | 1 | 1 | - |
| CA | C100 | agglutinin peptidase (Marasmius oreades) | 6 | 1 | 1 | 3 |
| CA | C101 | OTULIN peptidase | 349 | 2 | 1 | 2 |
| CA | C102 | GtgE peptidase | 1 | 1 | 1 | 1 |
| CA | C103 | HopX1 peptidase (Pseudomonas syringae) | 2 | 1 | 1 | - |
| CA | C104 | PlyC phage lysin | 27 | 1 | 1 | 1 |
| CA | C105 | family S32 unassigned peptidases | 1 | 1 | 1 | - |
| CA | C110 | kyphoscoliosis peptidase | 1311 | 1 | 1 | - |
| CA | C111 | coagulation factor XIIIa | 2292 | 10 | 2 | 1 |
| CA | C113 | IgdE peptidase (Streptococcus suis) | 69 | 1 | 1 | - |
| CA | C115 | MINDY-1 protein | 1206 | 2 | 1 | - |
| CA | C117 | SpvD g.p. (Salmonella enterica) | 9 | 1 | 1 | 1 |
| CA | C119 | LotA g.p. (Legionella pneumophila) | 41 | 1 | 1 | - |
| CA | C121 | MINDY-4 peptidase | 1055 | 2 | 1 | - |
| CA | C124 | Lem27 (Legionella pneumophila) | 41 | 1 | 1 | - |
| CD | C11 | clostripain | 1258 | 7 | 2 | 5 |
| CD | C13 | legumain (plant beta form) | 3649 | 13 | 2 | 4 |
| CD | C14 | caspase-1 | 9177 | 60 | 12 | 17 |
| CD | C25 | gingipain RgpA | 1393 | 4 | 3 | 3 |
| CD | C50 | separase (yeast-type) | 882 | 7 | 2 | 3 |
| CD | C80 | RTX self-cleaving toxin | 101 | 3 | 1 | 2 |
| CD | C84 | prtH peptidase (Tannerella forsythensis ATCC 43037) | 13 | 1 | 1 | - |
| CD | C123 | RARP2 (Rickettsia rickettsii) | 4 | 1 | 1 | - |
| CE | C5 | adenain | 146 | 1 | 2 | 1 |
| CE | C48 | Ulp1 peptidase | 5778 | 59 | 2 | 10 |
| CE | C55 | YopJ protein | 90 | 8 | 1 | 1 |
| CE | C57 | vaccinia virus I7L processing peptidase | 34 | 1 | 1 | - |
| CE | C63 | African swine fever virus processing peptidase | 1 | 1 | 1 | - |
| CE | C79 | ElaD peptidase (Escherichia-type) | 57 | 1 | 1 | 1 |
| CE | C122 | SdeA (Legionella pneumophila) | 10 | 1 | 1 | 1 |
| CF | C15 | pyroglutamyl-peptidase I (prokaryote) | 2475 | 9 | 2 | 1 |
| CL | C60 | sortase A (Staphylococcus-type) | 1919 | 9 | 3 | 6 |
| CL | C82 | L,D-transpeptidase (Enterococcus-type) | 9593 | 8 | 1 | 4 |
| CM | C18 | hepacivirin | 434 | 2 | 1 | 1 |
| CN | C9 | sindbis virus-type nsP2 peptidase | 81 | 2 | 1 | 2 |
| CO | C40 | dipeptidyl-peptidase VI (bacteria) | 18290 | 21 | 1 | 5 |
| CP | C97 | desumoylating isopeptidase 1 | 2368 | 14 | 1 | 1 |
| CQ | C53 | pestivirus Npro peptidase | 49 | 2 | 1 | 2 |
| CR | C108 | Prp peptidase (Staphylococcus aureus) | 834 | 2 | 1 | 2 |
| unassigned | C7 | chestnut blight fungus virus p29 peptidase | 12 | 1 | 1 | - |
| unassigned | C8 | chestnut blight fungus virus p48 peptidase | 7 | 1 | 1 | - |
| unassigned | C23 | carlavirus peptidase | 44 | 1 | 1 | - |
| unassigned | C27 | rubella virus peptidase | 1 | 1 | 1 | - |
| unassigned | C36 | beet necrotic yellow vein furovirus-type papain-like peptidase | 3 | 1 | 1 | - |
| unassigned | C42 | beet yellows virus-type papain-like peptidase | 10 | 4 | 1 | - |
| unassigned | C49 | Strawberry mottle virus 3C-like peptidase | 2 | 1 | 1 | - |
| unassigned | C75 | AgrB peptidase | 121 | 2 | 1 | - |
| unassigned | C106 | archaeosortase A (Haloferax volcanii ) | 118 | 1 | 1 | - |
| unassigned | C116 | dermonecrotic toxin (Pasteurella multocida) | 2 | 1 | 1 | 1 |
| unassigned | C118 | EspL g.p. (Escherichia coli) | 88 | 1 | 1 | - |
| unassigned | C120 | mavirus processing peptidase | 4 | 1 | 1 | - |
| PA | C3 | poliovirus-type picornain 3C | 1136 | 19 | 3 | 12 |
| PA | C4 | potyvirus P1 peptidase | 214 | 14 | 2 | 1 |
| PA | C24 | rabbit hemorrhagic disease virus 3C-like peptidase | 27 | 3 | 1 | 1 |
| PA | C30 | porcine transmissible gastroenteritis virus-type main peptidase | 99 | 7 | 2 | 7 |
| PA | C37 | calicivirin | 36 | 2 | 2 | 2 |
| PA | C62 | gill-associated virus 3C-like peptidase | 2 | 1 | 1 | - |
| PA | C74 | pestivirus Npro peptidase | 26 | 1 | 1 | 2 |
| PA | C99 | iflavirus processing peptidase | 3 | 1 | 1 | - |
| PA | C107 | alphamesonivirus 3C-like peptidase | 8 | 1 | 1 | 1 |
| PA | C125 | protease (sacbrood virus) | 75 | 1 | 1 | - |
| PB | C44 | amidophosphoribosyltransferase precursor | 10994 | 16 | 4 | 7 |
| PB | C45 | acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase precursor | 1082 | 2 | 1 | 1 |
| PB | C59 | penicillin V acylase precursor | 1969 | 2 | 2 | 3 |
| PB | C69 | dipeptidase A | 2310 | 6 | 1 | - |
| PB | C89 | acid ceramidase precursor | 700 | 4 | 1 | 2 |
| PB | C95 | lysosomal 66.3 kDa protein (Mus musculus-type) | 755 | 2 | 1 | 2 |
| PC | C26 | gamma-glutamyl hydrolase | 21267 | 44 | 15 | 17 |
| PC | C56 | PfpI peptidase | 13623 | 17 | 3 | 10 |
| PD | C46 | hedgehog protein | 1173 | 15 | 1 | 4 |
| Glutamic Peptidases | ||||||
| Clan | Family | Example | Sequences | Identifiers | Identifiers with EC numbers | Identifiers with PDB entries |
| GA | G1 | scytalidoglutamic peptidase | 943 | 6 | 3 | 2 |
| GB | G2 | pre-neck appendage protein (Bacillus phage phi29) | 125 | 1 | 1 | 1 |
| GC | G4 | Tiki1 peptidase | 1055 | 2 | 1 | - |
| GC | G6 | Ras/Rap1-specific peptidase | 100 | 1 | 1 | 1 |
| unassigned | G3 | strawberry mottle virus glutamic peptidase | 2 | 1 | 1 | - |
| unassigned | G5 | RCE1 peptidase (Saccharomyces cerevisiae-type) | 9185 | 11 | 1 | 1 |
| Metallo Peptidases | ||||||
| Clan | Family | Example | Sequences | Identifiers | Identifiers with EC numbers | Identifiers with PDB entries |
| MA | M1 | aminopeptidase N | 17730 | 65 | 10 | 13 |
| MA | M2 | angiotensin-converting enzyme peptidase unit 2 | 1390 | 9 | 3 | 4 |
| MA | M3 | thimet oligopeptidase | 16702 | 18 | 7 | 8 |
| MA | M4 | thermolysin | 6399 | 23 | 7 | 6 |
| MA | M5 | mycolysin | 145 | 1 | 2 | - |
| MA | M6 | immune inhibitor A peptidase (Bacillus sp.) | 3405 | 3 | 1 | 1 |
| MA | M7 | snapalysin | 1251 | 1 | 2 | 1 |
| MA | M8 | leishmanolysin | 2563 | 12 | 2 | 1 |
| MA | M9 | collagenase V (Vibrio spp.) | 1745 | 5 | 2 | 3 |
| MA | M10 | matrix metallopeptidase-1 | 12952 | 65 | 13 | 21 |
| MA | M11 | gametolysin | 229 | 3 | 2 | - |
| MA | M12 | astacin | 25399 | 242 | 32 | 36 |
| MA | M13 | neprilysin | 12551 | 49 | 3 | 4 |
| MA | M26 | IgA1-specific metallopeptidase | 2337 | 4 | 2 | - |
| MA | M27 | tentoxilysin | 68 | 4 | 3 | 4 |
| MA | M30 | hyicolysin | 468 | 1 | 1 | - |
| MA | M32 | carboxypeptidase Taq | 5269 | 6 | 2 | 5 |
| MA | M34 | anthrax lethal factor | 115 | 3 | 3 | 3 |
| MA | M35 | deuterolysin | 269 | 5 | 3 | 3 |
| MA | M36 | fungalysin | 742 | 2 | 1 | 1 |
| MA | M41 | FtsH peptidase | 11392 | 38 | 1 | 7 |
| MA | M43 | cytophagalysin | 1491 | 7 | 2 | 1 |
| MA | M48 | Ste24 peptidase | 12122 | 24 | 2 | 5 |
| MA | M49 | dipeptidyl-peptidase III | 1012 | 11 | 2 | 4 |
| MA | M54 | archaelysin | 734 | 3 | 1 | 1 |
| MA | M56 | BlaR1 peptidase | 2454 | 3 | 1 | 2 |
| MA | M57 | prtB g.p. (Myxococcus xanthus) | 50 | 1 | 1 | - |
| MA | M60 | enhancin | 83 | 6 | 1 | 1 |
| MA | M61 | glycyl aminopeptidase | 1404 | 2 | 1 | 1 |
| MA | M64 | IgA peptidase (Clostridium ramosum-type) | 104 | 1 | 1 | 1 |
| MA | M66 | StcE peptidase | 180 | 1 | 1 | 1 |
| MA | M72 | peptidyl-Asp metallopeptidase | 96 | 2 | 2 | - |
| MA | M76 | Atp23 peptidase (animal-type) | 831 | 5 | 1 | - |
| MA | M78 | ImmA peptidase | 1820 | 2 | 1 | 1 |
| MA | M80 | Wss1 peptidase (Saccharomyces-type) | 345 | 5 | 1 | 2 |
| MA | M84 | MpriBi peptidase (Bacillus sp.) | 24 | 1 | 1 | - |
| MA | M85 | NleC peptidase (Escherichia coli) | 12 | 1 | 1 | 1 |
| MA | M87 | chloride channel accessory protein 1 | 690 | 6 | 1 | - |
| MA | M88 | IMPa peptidase (Pseudomonas aeruginosa) | 31 | 1 | 1 | 1 |
| MA | M90 | MtfA peptidase | 1026 | 1 | 1 | 1 |
| MA | M91 | NleD peptidase (Escherichia coli-type) | 10 | 1 | 1 | - |
| MA | M93 | BACCAC_01431 g.p. (Bacteroides caccae) and similar | 232 | 1 | 1 | 1 |
| MA | M95 | abylysin (Pyrococcus abyssi) | 33 | 3 | 1 | 3 |
| MA | M97 | EcxAB peptidase | 150 | 1 | 1 | 1 |
| MA | M98 | YghJ g.p. (Escherichia coli) | 410 | 4 | 1 | - |
| MA | M100 | spartan peptidase | 32 | 1 | 1 | 1 |
| MA | M101 | flagellinolysin | 2 | 1 | 1 | - |
| MA | M102 | DA1 peptidase (Arabidopsis thaliana) | 471 | 1 | 1 | - |
| MA | M105 | MAP1 peptidase (Myxococcus xanthus, Pimelobacter sp.) | 330 | 1 | 1 | - |
| MA | M106 | FP0506 g.p. (Flavobacterium psychrophilum) | 399 | 1 | 1 | - |
| MC | M14 | carboxypeptidase A1 | 19935 | 76 | 13 | 17 |
| MC | M86 | PghP gamma-polyglutamate hydrolase (bacteriophage) | 152 | 1 | 1 | 1 |
| MC | M99 | Csd4 peptidase (Helicobacter pylori) | 1 | 1 | 1 | 1 |
| MD | M15 | zinc D-Ala-D-Ala carboxypeptidase (Streptomyces-type) | 10572 | 13 | 4 | 8 |
| MD | M74 | murein endopeptidase | 2295 | 1 | 1 | 1 |
| ME | M16 | pitrilysin | 27911 | 58 | 5 | 20 |
| ME | M44 | pox virus metallopeptidase | 39 | 1 | 1 | - |
| MF | M17 | leucyl aminopeptidase 3 | 5687 | 21 | 4 | 9 |
| MG | M24 | methionyl aminopeptidase 1 (Escherichia-type) | 23276 | 40 | 5 | 25 |
| MH | M18 | aminopeptidase I | 8514 | 6 | 3 | 5 |
| MH | M20 | glutamate carboxypeptidase | 47025 | 48 | 12 | 22 |
| MH | M28 | aminopeptidase S (Streptomyces-type) | 19466 | 46 | 5 | 18 |
| MH | M42 | glutamyl aminopeptidase (bacterium) | 3846 | 13 | 1 | 9 |
| MJ | M19 | membrane dipeptidase | 9245 | 13 | 2 | 8 |
| MJ | M38 | isoaspartyl dipeptidase (metallo-type) | 22536 | 15 | 7 | 14 |
| MM | M50 | site 2 peptidase | 9444 | 20 | 2 | 4 |
| MN | M55 | D-aminopeptidase DppA | 742 | 2 | 1 | 1 |
| MO | M23 | beta-lytic metallopeptidase | 10283 | 18 | 3 | 12 |
| MP | M67 | PSMD14 peptidase | 7179 | 31 | 2 | 15 |
| MQ | M29 | aminopeptidase T | 6498 | 4 | 1 | 2 |
| MS | M75 | imelysin | 328 | 1 | 1 | 1 |
| MT | M81 | microcystinase MlrC | 548 | 1 | 1 | 1 |
| MU | M103 | TldD peptidase (Escherichia coli) | 3340 | 4 | 1 | 5 |
| MV | M77 | tryptophanyl aminopeptidase 7-DMATS-type peptidase | 196 | 4 | 2 | 2 |
| unassigned | M73 | camelysin | 181 | 2 | 1 | 1 |
| unassigned | M82 | PrsW peptidase | 1170 | 1 | 1 | - |
| Asparagine Peptidases | ||||||
| Clan | Family | Example | Sequences | Identifiers | Identifiers with EC numbers | Identifiers with PDB entries |
| NA | N1 | nodavirus peptide lyase | 8 | 1 | 2 | 2 |
| NA | N2 | tetravirus coat protein | 7 | 1 | 1 | 2 |
| NA | N8 | poliovirus-type picornain 3C | 822 | 1 | 1 | 3 |
| NB | N6 | YscU protein | 1881 | 5 | 1 | 4 |
| NC | N7 | reovirus type 1 coat protein | 22 | 2 | 1 | 1 |
| ND | N4 | Tsh peptidase | 448 | 2 | 1 | 3 |
| NE | N5 | picobirnavirus self-cleaving protein | 6 | 1 | 1 | 1 |
| PD | N9 | intein-containing V-type proton ATPase catalytic subunit A | 88 | 1 | 2 | 1 |
| PD | N10 | intein-containing replicative DNA helicase precursor | 461 | 9 | 2 | 7 |
| PD | N11 | peptidase Clp (type 7) | 74 | 1 | 1 | - |
| Mixed Peptidases | ||||||
| Clan | Family | Example | Sequences | Identifiers | Identifiers with EC numbers | Identifiers with PDB entries |
| PB | P2 | EGF-like module containing mucin-like hormone receptor-like 2 | 5881 | 49 | 1 | 4 |
| PE | P1 | DmpA aminopeptidase | 692 | 5 | 2 | 5 |
| Serine Peptidases | ||||||
| Clan | Family | Example | Sequences | Identifiers | Identifiers with EC numbers | Identifiers with PDB entries |
| PA | S1 | chymotrypsin A (cattle-type) | 70933 | 704 | 58 | 141 |
| PA | S3 | togavirin | 85 | 1 | 2 | 1 |
| PA | S6 | IgA1-specific serine peptidase (Neisseria-type) | 1373 | 12 | 2 | 6 |
| PA | S7 | flavivirin | 360 | 2 | 2 | 3 |
| PA | S29 | hepacivirin | 236 | 2 | 2 | 2 |
| PA | S30 | potyvirus P1 peptidase | 97 | 2 | 1 | - |
| PA | S31 | pestivirus NS3 polyprotein peptidase | 32 | 1 | 2 | 1 |
| PA | S32 | equine arteritis virus serine peptidase | 121 | 2 | 2 | 2 |
| PA | S39 | sobemovirus peptidase | 71 | 2 | 1 | 2 |
| PA | S46 | dipeptidyl-peptidase 7 (Porphyromonas gingivalis-type) | 1028 | 4 | 1 | 2 |
| PA | S55 | SpoIVB peptidase | 339 | 1 | 2 | - |
| PA | S64 | Ssy5 peptidase | 40 | 1 | 1 | - |
| PA | S65 | picornain-like serine peptidase (Breda-1 torovirus) | 3 | 1 | 1 | - |
| PA | S75 | White bream virus serine peptidase | 1 | 1 | 1 | - |
| PB | S45 | penicillin G acylase precursor | 2556 | 5 | 2 | 4 |
| PC | S51 | dipeptidase E | 4376 | 3 | 3 | 3 |
| SB | S8 | subtilisin Carlsberg | 38224 | 210 | 18 | 46 |
| SB | S53 | sedolisin | 6031 | 13 | 6 | 4 |
| SC | S9 | prolyl oligopeptidase | 61060 | 213 | 18 | 49 |
| SC | S10 | carboxypeptidase Y | 10248 | 87 | 4 | 7 |
| SC | S15 | Xaa-Pro dipeptidyl-peptidase | 7478 | 1 | 2 | 3 |
| SC | S28 | lysosomal Pro-Xaa carboxypeptidase | 3596 | 31 | 3 | 2 |
| SC | S33 | prolyl aminopeptidase | 33239 | 151 | 10 | 24 |
| SC | S37 | PS-10 peptidase | 1191 | 1 | 1 | - |
| SC | S82 | autocrine proliferation repressor protein A (Dictyostelium discoideum) | 383 | 1 | 1 | - |
| SE | S11 | D-Ala-D-Ala carboxypeptidase A | 15883 | 12 | 2 | 9 |
| SE | S12 | D-Ala-D-Ala carboxypeptidase B | 29463 | 33 | 3 | 11 |
| SE | S13 | D-Ala-D-Ala peptidase C | 6481 | 6 | 2 | 3 |
| SF | S24 | repressor LexA | 14488 | 6 | 2 | 4 |
| SF | S26 | signal peptidase I | 19747 | 34 | 2 | 4 |
| SH | S21 | cytomegalovirus assemblin | 89 | 7 | 2 | 5 |
| SH | S73 | gpO peptidase (Enterobacteria phage P2) | 330 | 1 | 1 | - |
| SH | S77 | prohead peptidase gp21 (bacteriophage T4) | 116 | 1 | 1 | 1 |
| SH | S78 | prohead peptidase (bacteriophage HK97) | 1492 | 2 | 1 | - |
| SH | S80 | prohead peptidase gp175 (Pseudomonas aeruginosa phage phiKZ) | 7 | 2 | 1 | - |
| SJ | S16 | Lon-A peptidase | 21382 | 25 | 2 | 8 |
| SJ | S50 | infectious pancreatic necrosis birnavirus Vp4 peptidase | 24 | 4 | 2 | 2 |
| SJ | S69 | Tellina virus 1 VP4 peptidase | 1 | 1 | 1 | 1 |
| SK | S14 | peptidase Clp (type 1) | 17300 | 15 | 2 | 13 |
| SK | S41 | C-terminal processing peptidase-1 | 14449 | 20 | 2 | 8 |
| SK | S49 | signal peptide peptidase A (Pseudomonas aeruginosa) | 15503 | 9 | 1 | 3 |
| SO | S74 | Escherichia coli phage K1F endosialidase CIMCD self-cleaving protein | 66 | 3 | 1 | 3 |
| SP | S59 | nucleoporin 145 | 1200 | 11 | 1 | 6 |
| SR | S60 | lactoferrin | 1127 | 11 | 1 | 5 |
| SS | S66 | murein tetrapeptidase LD-carboxypeptidase (Pseudomonas-type) | 3554 | 3 | 2 | 4 |
| ST | S54 | rhomboid-1 (Diptera) | 13499 | 53 | 2 | 3 |
| unassigned | S48 | HetR putative peptidase | 88 | 1 | 1 | 1 |
| unassigned | S62 | influenza A PA peptidase | 52 | 1 | 1 | 3 |
| unassigned | S68 | PIDD auto-processing protein unit 1 | 171 | 2 | 1 | - |
| unassigned | S71 | MUC1 self-cleaving mucin | 672 | 2 | 1 | 1 |
| unassigned | S72 | dystroglycan | 367 | 2 | 1 | 1 |
| unassigned | S79 | CARD8 self-cleaving protein | 540 | 7 | 1 | 1 |
| unassigned | S81 | destabilase | 353 | 1 | 1 | 1 |
| unassigned | S85 | small protease (Pseudomonas aeruginosa) | 39 | 1 | 1 | 1 |
| Threonine Peptidases | ||||||
| Clan | Family | Example | Sequences | Identifiers | Identifiers with EC numbers | Identifiers with PDB entries |
| PB | T1 | archaean proteasome, beta component | 22654 | 62 | 3 | 39 |
| PB | T2 | glycosylasparaginase precursor | 3991 | 9 | 2 | 6 |
| PB | T3 | gamma-glutamyltransferase 1 (bacterial-type) | 8668 | 30 | 6 | 4 |
| PB | T7 | CwpV (Clostridium difficile) self-cleaving threonine peptidase | 5 | 1 | 1 | - |
| PE | T5 | ornithine acetyltransferase precursor | 3774 | 2 | 2 | 2 |
| unassigned | T8 | HopB1 g.p. (Pseudomonas syringae) | 323 | 1 | 1 | - |
| Unknown Peptidases | ||||||
| Clan | Family | Example | Sequences | Identifiers | Identifiers with EC numbers | Identifiers with PDB entries |
| unassigned | U32 | collagenase (Porphyromonas-type) | 2735 | 6 | 1 | 2 |
| unassigned | U40 | protein P5 murein endopeptidase (bacteriophage phi-6) | 2 | 1 | 1 | 1 |
| unassigned | U49 | Lit peptidase | 10 | 1 | 1 | - |
| unassigned | U56 | homomultimeric peptidase | 238 | 1 | 1 | 2 |
| unassigned | U57 | yabG protein (Bacillus-type) | 205 | 1 | 1 | - |
| unassigned | U69 | AIDA-I self-cleaving autotransporter protein (Escherichia coli) | 664 | 2 | 1 | 2 |
| unassigned | U72 | Dop isopeptidase | 538 | 1 | 1 | 2 |
| unassigned | U74 | neprosin | 2091 | 1 | 1 | - |
| Unclassifiable Peptidases | ||||||
| Clan | Family | Example | Sequences | Identifiers | Identifiers with EC numbers | Identifiers with PDB entries |
| unassignable | unassignable | 3 | 3 | 24 | - | |
