$VAR1 = undef;
Summary for peptidase M12.244: ADAM33 peptidase
| Names | |
|---|---|
| MEROPS Name | ADAM33 peptidase |
| Domain architecture |
|---|
| MEROPS Classification | |
|---|---|
| Classification | Clan MA >> Subclan MA(M) >> Family M12 >> Subfamily B >> M12.244 |
| Holotype | ADAM33 peptidase (Mus musculus), Uniprot accession Q923W9 (peptidase unit: 207-410), MERNUM MER0015147 |
| History | Identifier created: MEROPS 6.0 (30 August 2002) |
| Activity | |||
|---|---|---|---|
| Catalytic type | Metallo | ||
| NC-IUBMB | Not yet included in IUBMB recommendations. | ||
| Proteolytic events | CutDB database (3 cleavages) | ||
| Activity status | human: active (Zou et al., 2004) mouse: putative | ||
| Pharmaceutical relevance | There is evidence that polymorphisms in ADAM33 predispose to asthma (Van Eerdewegh et al., 2002; Howard et al., 2003; Werner et al., 2004). | ||
| Other databases | WIKIPEDIA | http://en.wikipedia.org/wiki/ADAM33 | |
| Human genetics | ||||||
|---|---|---|---|---|---|---|
| Gene symbol | Locus | Megabases | Ensembl | Entrez gene | Gene Cards | OMIM |
| ADAM33 | 20p13 | ENSG00000149451 | 80332 | 607114 | ||
| Mouse genetics | ||||||
| Gene symbol | Position | Megabases | Ensembl | Entrez gene | MGI | |
| Adam33 | 2:F2 | ENSMUSG00000027318 | 110751 | MGI:1341813 | ||
