$VAR1 = undef;

Summary for peptidase C48.004: SENP6 peptidase

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Literature Substrates

 

Names
MEROPS NameSENP6 peptidase
Other namesSUSP1, SUMO-1-specific protease 6
Domain architecture
MEROPS Classification
Classification Clan CE >> Subclan (none) >> Family C48 >> Subfamily (none) >> C48.004
HolotypeSENP6 peptidase (Homo sapiens), Uniprot accession Q9GZR1 (peptidase unit: 672-1042), MERNUM MER0011109
History Identifier created: MEROPS 5.0 (17 April 2000)
Activity
Catalytic typeCysteine
NC-IUBMBNot yet included in IUBMB recommendations.
Activity statushuman: active (Kim et al., 2000)
mouse: active (by similarity to human) (Kim et al., 2000)
Other databases TREEFAMhttp://www.treefam.org/family/TF350136
Cleavage site specificity Explanations of how to interpret the following cleavage site sequence logo and specificity matrix can be found here.
Cleavage patternQ/T/G/GScissile bondK/-/E/- (based on 13 cleavages)
weblogo
Specificity matrix
 
Amino acid P4 P3 P2 P1 P1' P2' P3' P4'
Gly 0 0 13 13 0 0 0 0
Pro 0 0 0 0 0 0 1 0
Ala 0 0 0 0 0 0 1 1
Val 0 0 0 0 0 1 0 0
Leu 1 0 0 0 0 0 0 0
Ile 0 0 0 0 0 0 0 0
Met 0 0 0 0 0 1 0 0
Phe 0 0 0 0 0 0 0 0
Tyr 0 0 0 0 0 0 0 0
Trp 0 0 0 0 0 0 0 0
Ser 0 0 0 0 0 1 0 1
Thr 0 12 0 0 0 1 0 1
Cys 0 0 0 0 0 1 0 0
Asn 0 0 0 0 0 0 0 2
Gln 12 0 0 0 0 0 0 0
Asp 0 0 0 0 0 0 0 0
Glu 0 0 0 0 0 1 5 0
Lys 0 0 0 0 11 0 0 1
Arg 0 1 0 0 0 0 0 1
His 0 0 0 0 0 1 0 0
Human genetics
Gene symbol Locus Megabases Ensembl Entrez gene Gene Cards OMIM
SENP6 6q13-q14.3 ENSG00000112701 26054 SENP6 605003
Mouse genetics
Gene symbol Position Megabases Ensembl Entrez gene MGI
Senp6 9:E1 ENSMUSG00000034252 215351 MGI:1922075