$VAR1 = undef;

Summary for XM02.001

Summary Substrates

 

Names
MEROPS Nameangiotensin-converting enzyme compound peptidase
MEROPS Classification
Holotypeangiotensin-converting enzyme peptidase unit 2 (Homo sapiens), Uniprot accession P12821 (peptidase unit: 641-1258), MERNUM MER0001019
Activity
Catalytic typeMetallo
NC-IUBMBNot yet included in IUBMB recommendations.
Proteolytic eventsCutDB database (4 cleavages)
Cleavage site specificity Explanations of how to interpret the following cleavage site sequence logo and specificity matrix can be found here.
Cleavage pattern-/-/-/-Scissile bond-/plf/-/- (based on 27 cleavages)
weblogo
Specificity matrix
 
Amino acid P4 P3 P2 P1 P1' P2' P3' P4'
Gly 3 3 3 4 3 2 2 1
Pro 2 1 3 2 1 7 0 1
Ala 0 0 0 0 0 1 1 0
Val 0 1 0 0 0 0 1 0
Leu 0 1 0 2 0 6 0 1
Ile 1 0 0 1 1 0 0 0
Met 1 0 1 3 0 2 1 0
Phe 2 3 4 5 4 4 1 1
Tyr 1 3 1 2 1 1 0 0
Trp 0 0 2 1 1 0 1 0
Ser 1 0 5 1 3 0 0 0
Thr 0 0 1 0 0 0 0 0
Cys 0 0 0 0 0 0 0 0
Asn 0 0 0 0 0 0 0 0
Gln 1 1 0 0 1 0 0 0
Asp 0 0 0 2 1 0 0 0
Glu 0 0 1 0 1 0 1 0
Lys 0 0 0 1 3 0 1 0
Arg 2 1 1 2 2 2 0 1
His 0 1 1 1 4 1 0 1