$VAR1 = undef;

Summary for peptidase C30.007: coronavirus COVID-19 3C-like peptidase

Names
MEROPS Name	coronavirus COVID-19 3C-like peptidase
Other names	3CL(pro), 3CLpro, 3-chymotrypsin-like protease, COVID-19 virus main protease, nsp5, Mpro, SARS-CoV-2 main protease, SARS-CoV-2 M(pro) protease

MEROPS Classification
Classification	Clan PA >> Subclan PA(C) >> Family C30 >> Subfamily (none) >> C30.007

Activity
Catalytic type	Cysteine
NC-IUBMB	Not yet included in IUBMB recommendations.
Cleavage site specificity	Explanations of how to interpret the following cleavage site sequence logo and specificity matrix can be found here.
Cleavage pattern	asv/lr/Lqfg/Qsag/-/-/- (based on 28 cleavages)

Specificity matrix

Amino acid	P4	P3	P2	P1	P1'	P2'	P3'	P4'
Gly	0	0	2	4	5	4	1	1
Pro	1	0	0	0	0	0	3	3
Ala	6	1	0	1	6	5	1	3
Val	6	2	1	1	1	0	2	1
Leu	3	8	17	0	1	1	2	2
Ile	1	2	0	0	0	2	0	1
Met	0	1	0	0	0	0	2	0
Phe	0	0	2	0	0	0	2	0
Tyr	0	0	0	0	0	1	1	2
Trp	0	0	0	0	0	0	0	0
Ser	6	1	0	2	8	0	1	3
Thr	2	4	0	0	1	2	1	1
Cys	1	0	0	0	1	0	0	1
Asn	0	0	0	0	2	3	4	2
Gln	1	1	6	20	2	4	1	1
Asp	0	0	0	0	0	0	1	1
Glu	0	1	0	0	1	1	2	1
Lys	1	1	0	0	0	2	1	1
Arg	0	6	0	0	0	1	0	1
His	0	0	0	0	0	1	2	2