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M-CSA ID Enzyme Name Uniprot InterPro EC PDB Catalytic CATH
1 glutamate racemase IPR004391 5.1.1.3 1b73 3.40.50.1860
2 beta-lactamase (Class A) IPR000871 3.5.2.6 1btl 3.40.710.10
3 NAD(P)H dehydrogenase (quinone) IPR003680 1.6.5.2 1d4a 3.40.50.360
4 nitrite reductase (copper type) IPR001287 1.7.2.1 1nia 2.60.40.420
5 carboxypeptidase D IPR001563 3.4.16.6 1whs 3.40.50.1820, 3.40.50.11320
6 glutathione-disulfide reductase IPR006322 1.8.1.7 2gh5 3.30.390.30, 3.50.50.60
7 isocitrate dehydrogenase (NADP+) IPR004439 1.1.1.42 5icd 3.40.718.10
8 nicotinate-nucleotide diphosphorylase (carboxylating) (type II) IPR004393 2.4.2.19 1qpr 3.20.20.70, 3.90.1170.20
9 methionine adenosyltransferase IPR002133 2.5.1.6 5a1i 3.30.300.10
10 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase IPR010083 4.2.1.59 1mkb 3.10.129.10
11 deoxyribonuclease IV (phage-T4-induced) IPR001719 3.1.21.2 1qum 3.20.20.150
12 ornithine carbamoyltransferase IPR002292 2.1.3.3 1oth 3.40.50.1370
13 amine dehydrogenase IPR004229 1.4.9.1 2bbk 2.130.10.10, 2.60.30.10
14 chloride peroxidase (vanadate dependent) IPR000326 1.11.1.10 1vnc 1.10.606.10
15 beta-lactamase (Class B1) IPR001279 3.5.2.6 1znb 3.60.15.10
16 beta-lactamase (Class B1) IPR001279 3.5.2.6 1bc2 3.60.15.10
17 purine-nucleoside phosphorylase IPR011270 2.4.2.1 1rr6 3.40.50.1580
18 glycine amidinotransferase IPR033195 2.1.4.1 1jdw 3.75.10.10
19 mannosyl-oligosaccharide 1,2-alpha-mannosidase IPR001382 3.2.1.113 1x9d 1.50.10.10
20 fumarate reductase (quinol) IPR010960 1.3.5.4 1qjd 3.50.50.60, 3.90.700.10
21 malate dehydrogenase (oxaloacetate-decarboxylating) IPR001891 1.1.1.38 1do8 3.40.50.10380, 3.40.50.720
22 aralkylamine N-acetyltransferase IPR016181 2.3.1.87 1b6b 3.40.630.30
23 glycine N-methyltransferase IPR014369 2.1.1.20 1xva 3.30.46.10, 3.40.50.150
24 4-chlorobenzoyl-CoA dehalogenase IPR001753 3.8.1.7 1nzy 3.90.226.10
25 N-carbamoylsarcosine amidase IPR000868 3.5.1.59 1nba 3.40.50.850
26 phosphatidylinositol diacylglycerol-lyase IPR017946 4.6.1.13 1ptd 3.20.20.190
27 phospholipase C IPR008947 3.1.4.3 1ah7 1.10.575.10
28 phosphoinositide phospholipase C IPR028391 3.1.4.11 1djx 3.20.20.190
29 glutamin-(asparagin-)ase IPR004550 3.5.1.38 1djo 3.40.50.40, 3.40.50.1170
30 formate C-acetyltransferase IPR005949 2.3.1.54 2pfl 3.20.70.20
31 thymidylate synthase IPR000398 2.1.1.45 1lcb 3.30.572.10
32 lactoylglutathione lyase IPR004361 4.4.1.5 1qin 3.10.180.10
33 methylmalonyl-CoA epimerase IPR017515 5.1.99.1 1jc5 3.10.180.10
34 catechol 2,3-dioxygenase IPR017624 1.13.11.2 1mpy 3.10.180.10
35 phosphorylase kinase IPR002291 2.7.11.19 2phk 1.10.510.10
36 (S)-2-haloacid dehalogenase IPR006439 3.8.1.2 1qq5 3.40.50.1000, 1.10.150.240
37 prostaglandin-endoperoxide synthase IPR029576 1.14.99.1 5cox 1.10.640.10
38 GTP cyclohydrolase I IPR001474 3.5.4.16 1fbx 3.30.1130.10
39 inosine-uridine preferring nucleoside hydrolase IPR023186 3.2.2.1 2mas 3.90.245.10
40 phosphoglycerate kinase IPR027250 2.7.2.3 13pk 3.40.50.1260
41 deoxyribonuclease I IPR016202 3.1.21.1 1dnk 3.60.10.10
42 nuclease IPR001604 3.1.30.2 1ql0 3.40.570.10
43 purple acid phosphatase IPR015914 3.1.3.2 4kbp 3.60.21.10
44 alkaline phosphatase IPR001952 3.1.3.1 1alk 3.40.720.10
45 cyclomaltodextrin glucanotransferase IPR006047 2.4.1.19 1cdg 3.20.20.80
46 site-specific DNA-methyltransferase (adenine-specific) IPR021188 2.1.1.72 2adm 3.40.50.150
47 protein-tyrosine-phosphatase non-receptor class IPR003546 3.1.3.48 1ytw 3.90.190.10
48 hypoxanthine phosphoribosyltransferase IPR005904 2.4.2.8 1bzy 3.40.50.2020
49 histidine decarboxylase IPR003427 4.1.1.22 1pya 3.50.20.10, 4.10.510.10
50 orotidine-5'-phosphate decarboxylase IPR014732 4.1.1.23 1dbt 3.20.20.70
51 phosphoenolpyruvate carboxykinase (ATP) IPR001272 4.1.1.49 1aq2 2.170.8.10, 3.40.449.10, 3.90.228.20
52 fructose-bisphosphate aldolase (Class II) IPR006411 4.1.2.13 1b57 3.20.20.70
53 malate synthase IPR006253 2.3.3.9 1d8c 3.20.20.360, 1.20.1220.12
54 3-dehydroquinate dehydratase (type I) IPR001381 4.2.1.10 1qfe 3.20.20.70
55 3-dehydroquinate dehydratase (type II) IPR001874 4.2.1.10 1gu1 3.40.50.9100
56 tRNA-pseudouridine synthase IPR020103 5.4.99.25 1ze1 3.30.2350.10
57 nitrile hydratase IPR018141,IPR003168 4.2.1.84 2ahj 3.90.330.10, 1.10.472.20
58 adenylate cyclase IPR030672 4.6.1.1 1cju 3.30.70.1230
59 3-dehydroquinate synthase IPR030960 4.2.3.4 1dqs 1.20.1090.10, 3.40.50.1970
60 glucosamine-6-phosphate deaminase IPR004547 3.5.99.6 1dea 3.40.50.1360
61 2-hydroxymuconate tautomerase IPR018191 5.3.2.6 1bjp 3.30.429.10
62 methylmalonyl-CoA mutase IPR006099,IPR006099 5.4.99.2 1req 3.40.50.280, 3.20.20.240
63 methylaspartate mutase IPR006396,IPR006394 5.4.99.1 1cb7 3.40.50.280, 3.20.20.240
64 DNA topoisomerase (type III) IPR005738 5.6.2.1 1d6m 1.10.290.10, 3.40.50.140
65 adenylosuccinate synthase IPR001114 6.3.4.4 1gim 3.40.440.10
66 D-alanine transaminase IPR005784 2.6.1.21 1daa 3.20.10.10, 3.30.470.10
67 alanine dehydrogenase IPR008141 1.4.1.1 1pjb 3.40.50.720
68 isovaleryl-CoA dehydrogenase IPR034183 1.3.8.4 1ivh 1.20.140.10, 2.40.110.10
69 acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase IPR010137 2.3.1.129 1lxa 2.160.10.10
70 methylmalonyl-CoA decarboxylase IPR001753 7.2.4.3 1ef8 3.90.226.10
71 uridine nucleosidase (family I) IPR002043 3.2.2.3 1eug 3.40.470.10
72 L-fuculose-phosphate aldolase IPR004782 4.1.2.17 2fua 3.40.225.10
73 4a-hydroxytetrahydrobiopterin dehydratase IPR001533 4.2.1.96 1dco 3.30.1360.20
74 dethiobiotin synthase IPR004472 6.3.3.3 1bs1 3.40.50.300
75 aspartate-ammonia ligase IPR004618 6.3.1.1 12as 3.30.930.10
76 NAD+ ADP-ribosyltransferase IPR008288 2.4.2.30 1a26 3.90.228.10
77 acetyl-CoA C-acyltransferase IPR002155 2.3.1.16 1afw 3.40.47.10
78 citrate (Si)-synthase IPR002020 2.3.3.1 1al6 1.10.230.10, 1.10.580.10
79 nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase IPR017846 2.4.2.21 1d0s 3.40.50.10210
80 adenylosuccinate lyase IPR004769 4.3.2.2 1c3c 1.10.275.10, 1.20.200.10
81 chorismate mutase (AroQ) IPR020822 5.4.99.5 3csm 1.10.590.10
82 glutamine-fructose-6-phosphate transaminase (isomerizing) IPR005855 2.6.1.16 1jxa 3.60.20.10, 3.40.50.10490
83 phospholipase A2 (group IB) IPR001211 3.1.1.4 1l8s 1.20.90.10
84 6-pyruvoyltetrahydropterin synthase IPR007115 4.2.3.12 1b66 3.30.479.10
85 methylglyoxal synthase IPR004363 4.2.3.3 1b93 3.40.50.1380
86 arginine kinase IPR000749 2.7.3.3 1bg0 3.30.590.10
87 urease IPR005848 3.5.1.5 1fwj 3.20.20.140
88 UDP-glucose-hexose-1-phosphate uridylyltransferase IPR001937 2.7.7.12 1hxq 3.30.428.10
89 pentalenene synthase IPR034686 4.2.3.7 1ps1 1.10.600.10
90 adenosylhomocysteinase IPR034373 3.3.1.1 1b3r 3.40.50.1480, 3.40.50.720
91 pyrimidine-nucleoside phosphorylase IPR018090 2.4.2.2 1brw 3.40.1030.10
92 UDP-glucose 6-dehydrogenase IPR028357 1.1.1.22 1dli 1.10.1040.10, 3.40.50.720
93 hydroxymethylglutaryl-CoA reductase (NADPH) IPR004816 1.1.1.34 1dqa 3.90.770.10, 3.30.70.420
94 1-alkyl-2-acetylglycerophosphocholine esterase IPR013830 3.1.1.47 1bwp 3.40.50.1110
95 L-fucose isomerase IPR005763 5.3.1.25 1fui 3.20.14.10, 3.40.275.10
96 creatinase IPR000994 3.5.3.3 1chm 3.90.230.10
97 cytidine deaminase IPR020797 3.5.4.5 1ctt 3.40.140.10
98 peptide deformylase IPR023635 3.5.1.88 1bsz 3.90.45.10
99 methanol dehydrogenase (cytochrome c) IPR017512 1.1.2.7 1g72 2.140.10.10
100 betaine-aldehyde dehydrogenase IPR015590 1.2.1.8 1a4s 3.40.309.10, 3.40.605.10
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