PDBe 1c3c

X-ray diffraction
1.8Å resolution

T. MARITIMA ADENYLOSUCCINATE LYASE

Released:

Function and Biology Details

Reaction catalysed:
(1) N(6)-(1,2-dicarboxyethyl)AMP = fumarate + AMP. (2) (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate = fumarate + 5-amino-1-(5-phospho-D- ribosyl)imidazole-4-carboxamide. 
Biochemical function:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Adenylosuccinate lyase Chains: A, B
Molecule details ›
Chains: A, B
Length: 429 amino acids
Theoretical weight: 49.69 KDa
Source organism: Thermotoga maritima
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9X0I0 (Residues: 2-430; Coverage: 100%)
Gene names: TM_1095, purB
Sequence domains:
Structure domains:

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X8C
Spacegroup: C2221
Unit cell:
a: 120.809Å b: 126.753Å c: 169Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.179 0.179 0.207
Expression system: Escherichia coli