EC 1.1.1.38 - Malate dehydrogenase (oxaloacetate-decarboxylating)

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IntEnz Enzyme Nomenclature
EC 1.1.1.38

Names

Accepted name:
malate dehydrogenase (oxaloacetate-decarboxylating)
Other names:
malic enzyme [ambiguous]
NAD-linked malic enzyme [ambiguous]
NAD-malic enzyme
NAD-specific malic enzyme
pyruvic-malic carboxylase
Systematic name:
(S)-malate:NAD+ oxidoreductase (oxaloacetate-decarboxylating)

Reactions

Comments:

Unlikef EC 1.1.1.39, malate dehydrogenase (decarboxylating), this enzyme can also decarboxylate oxaloacetate. cf. EC 1.1.1.40, malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+).

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ERGO , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Protein domains and families: PROSITE:PDOC00294
Structural data: CSA , EC2PDB
Gene Ontology: GO:0004471 , GO:0008948
CAS Registry Number: 9080-52-8
UniProtKB/Swiss-Prot: (120) [show] [UniProt]

References

  1. Kaufman, S., Korkes, S. and del Campillo, A.
    Biosynthesis of dicarboxylic acids by carbon dioxide fixation. V. Further studies of the "malic" enzyme of Lactobacillus arabinosus.
    J. Biol. Chem. 192: 301-312 (1951). [PMID: 14917678]
  2. Yamaguchi, M.
    Studies on regulatory functions of malic enzymes. IV. Effects of sulfhydryl group modification on the catalytic function of NAD-linked malic enzyme from Escherichia coli.
    J. Biochem. 86: 325-333 (1979). [PMID: 225306]

[EC 1.1.1.38 created 1961]