PDBe 1ctt

X-ray diffraction
2.2Å resolution

TRANSITION-STATE SELECTIVITY FOR A SINGLE OH GROUP DURING CATALYSIS BY CYTIDINE DEAMINASE

Released:

Function and Biology Details

Reaction catalysed:
(1) Cytidine + H(2)O = uridine + NH(3). (2) 2'-deoxycytidine + H(2)O = 2'-deoxyuridine + NH(3). 
Biochemical function:
Cellular component:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cytidine deaminase Chain: A
Molecule details ›
Chain: A
Length: 294 amino acids
Theoretical weight: 31.57 KDa
Source organism: Escherichia coli
Expression system: Not provided
UniProt:
  • Canonical: P0ABF6 (Residues: 1-294; Coverage: 100%)
Gene names: JW2131, b2143, cdd
Sequence domains:
Structure domains: Cytidine Deaminase, domain 2

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P3121
Unit cell:
a: 120.3Å b: 120.3Å c: 78.4Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.19 0.19 not available
Expression system: Not provided