EC 4.2.1.84 - Nitrile hydratase

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IntEnz Enzyme Nomenclature
EC 4.2.1.84

Names

Accepted name:
nitrile hydratase
Other names:
3-cyanopyridine hydratase
H-NHase
L-NHase
NHase
acrylonitrile hydratase
aliphatic nitrile hydratase
nitrilase [ambiguous]
nitrile hydro-lyase
Systematic name:
aliphatic-amide hydro-lyase (nitrile-forming)

Reaction

Comments:

Acts on short-chain aliphatic nitriles, converting them into the corresponding acid amides. Does not act on these amides or on aromatic nitriles. cf. EC 3.5.5.1 nitrilase.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UM-BBD , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0080109 , GO:0018822
CAS Registry Number: 82391-37-5
UniProtKB/Swiss-Prot: (15) [show] [UniProt]

References

  1. Asano, Y., Fujishiro, K., Tani, Y. and Yamada, H.
    Microbial degradation of nitrile compounds. 5. Aliphatic nitrile hydratase from Arthrobacter sp J-1. Purification and characterization.
    Agric. Biol. Chem. 46: 1165-1174 (1982).

[EC 4.2.1.84 created 1989]