EC 4.2.1.96 - 4a-hydroxytetrahydrobiopterin dehydratase

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IntEnz Enzyme Nomenclature
EC 4.2.1.96

Names

Accepted name:
4a-hydroxytetrahydrobiopterin dehydratase
Other names:
4α-hydroxy-tetrahydropterin dehydratase
pterin-4α-carbinolamine dehydratase
tetrahydrobiopterin dehydratase
4a-hydroxytetrahydrobiopterin hydro-lyase
Systematic name:
(6R)-6-(L-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterin hydro-lyase [(6R)-6-(L-erythro-1,2-dihydroxypropyl)-7,8-dihydro-6H-pterin-forming]

Reaction

Comments:

Catalyses the dehydration of 4a-hydroxytetrahydrobiopterins.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , DIAGRAM , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0008124
UniProtKB/Swiss-Prot: (256) [show] [UniProt]

References

  1. Hauer, C.R., Rebrin, I., Thöny, B., Neuheiser, F., Curtius, H.C., Hunziker, P., Blau, N., Ghisla, S., Heizmann, C.W.
    Phenylalanine hydroxylase-stimulating protein: pterin-4α-carbinolamine dehydratase from rat and human liver.
    J. Biol. Chem. 268: 4828-4831 (1993). [PMID: 8444860]

[EC 4.2.1.96 created 1999]