PDBe 1qpr

X-ray diffraction
2.45Å resolution

QUINOLINATE PHOSPHORIBOSYLTRANSFERASE (QAPRTASE) FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH PHTHALATE AND PRPCP

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Nicotinate-nucleotide pyrophosphorylase [carboxylating] Chains: A, B, C, D, E, F
Molecule details ›
Chains: A, B, C, D, E, F
Length: 284 amino acids
Theoretical weight: 29.85 KDa
Source organism: Mycobacterium tuberculosis H37Rv
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P9WJJ7 (Residues: 2-285; Coverage: 100%)
Gene names: MTCY336.08c, Rv1596, nadC
Sequence domains:
Structure domains:

Ligands and Environments

3 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RUH2R
Spacegroup: P31
Unit cell:
a: 100.448Å b: 100.448Å c: 145.792Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.186 0.186 0.251
Expression system: Escherichia coli BL21(DE3)