PDBe 1pya

X-ray diffraction
2.5Å resolution

REFINED STRUCTURE OF THE PYRUVOYL-DEPENDENT HISTIDINE DECARBOXYLASE FROM LACTOBACILLUS 30A

Released:

Function and Biology Details

Reaction catalysed:
L-histidine = histamine + CO(2). 
Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero hexamer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Histidine decarboxylase beta chain Chains: A, C, E
Molecule details ›
Chains: A, C, E
Length: 81 amino acids
Theoretical weight: 8.85 KDa
Source organism: Lactobacillus sp. 30A
Expression system: Not provided
UniProt:
  • Canonical: P00862 (Residues: 2-82; Coverage: 26%)
Gene name: hdcA
Structure domains: Pyruvoyl-Dependent Histidine Decarboxylas, subunit A
Histidine decarboxylase alpha chain Chains: B, D, F
Molecule details ›
Chains: B, D, F
Length: 229 amino acids
Theoretical weight: 25.29 KDa
Source organism: Lactobacillus sp. 30A
Expression system: Not provided
UniProt:
  • Canonical: P00862 (Residues: 84-311; Coverage: 73%)
Gene name: hdcA
Structure domains: Pyruvoyl-Dependent Histidine Decarboxylase, subunit B

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: I4122
Unit cell:
a: 221.7Å b: 221.7Å c: 107.1Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.15 0.15 not available
Expression system: Not provided