PDBe 1b66

X-ray diffraction
1.9Å resolution

6-PYRUVOYL TETRAHYDROPTERIN SYNTHASE

Released:

Function and Biology Details

Reaction catalysed:
7,8-dihydroneopterin 3'-triphosphate = 6-pyruvoyl-5,6,7,8- tetrahydropterin + triphosphate. 
Biochemical function:
Cellular component:

Structure analysis Details

Assemblies composition:
homo hexamer
homo trimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
6-pyruvoyl tetrahydrobiopterin synthase Chains: A, B
Molecule details ›
Chains: A, B
Length: 140 amino acids
Theoretical weight: 15.88 KDa
Source organism: Rattus rattus
Expression system: Escherichia coli
UniProt:
  • Canonical: P27213 (Residues: 5-144; Coverage: 97%)
Gene name: Pts
Sequence domains: 6-pyruvoyl tetrahydropterin synthase
Structure domains: Tetrahydropterin Synthase; Chain A

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: MPG/DESY, HAMBURG BEAMLINE BW6
Spacegroup: P321
Unit cell:
a: 120.27Å b: 120.27Å c: 61.25Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.227 0.227 0.258
Expression system: Escherichia coli