PDBe 1afw

X-ray diffraction
1.8Å resolution

THE 1.8 ANGSTROM CRYSTAL STRUCTURE OF THE DIMERIC PEROXISOMAL THIOLASE OF SACCHAROMYCES CEREVISIAE

Released:

Function and Biology Details

Reaction catalysed:
Acyl-CoA + acetyl-CoA = CoA + 3-oxoacyl-CoA. 
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
3-ketoacyl-CoA thiolase, peroxisomal Chains: A, B
Molecule details ›
Chains: A, B
Length: 393 amino acids
Theoretical weight: 42.08 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P27796 (Residues: 25-417; Coverage: 94%)
Gene names: FOX3, POT1, POX3, YIL160C
Sequence domains:
Structure domains: Peroxisomal Thiolase; Chain A, domain 1

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID2
Spacegroup: P212121
Unit cell:
a: 71.17Å b: 92.65Å c: 116.72Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.187 0.203 0.24