CHEBI:15428 - glycine

ChEBI IDCHEBI:15428
ChEBI Nameglycine
Stars
DefinitionThe simplest (and the only achiral) proteinogenic amino acid, with a hydrogen atom as its side chain.
Secondary ChEBI IDsCHEBI:5460, CHEBI:10792, CHEBI:14344, CHEBI:24368, CHEBI:42964
Last Modified16 April 2024
SubmitterMarcus Ennis
DownloadsMolfile
FormulaC2H5NO2
Net Charge0
Average Mass75.067
Monoisotopic Mass75.03203
SMILESNCC(=O)O
InChIInChI=1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)
InChIKeyDHMQDGOQFOQNFH-UHFFFAOYSA-N
Wikipedia
Species of MetaboliteComponentSourceComments
Homo sapiens (ncbitaxon:9606) - DOI (10.1038/nbt.2488)
Daphnia magna (ncbitaxon:35525) - PubMed (20117838)
Chlamydomonas reinhardtii (ncbitaxon:3055) - PubMed (25515814)
Saccharomyces cerevisiae (ncbitaxon:4932) - PubMed (24678285) Source: yeast.sf.net
Escherichia coli (ncbitaxon:562) - PubMed (21988831)
Mus musculus (ncbitaxon:10090) - PubMed (19425150) Source: BioModels - MODEL1507180067
Roles Classification
Chemical Roles:
Bronsted base  A molecular entity capable of accepting a hydron from a donor (Brønsted acid).
Bronsted acid  A molecular entity capable of donating a hydron to an acceptor (Brønsted base).
Biological Roles:
NMDA receptor agonist  An excitatory amino acid agonist which binds to NMDA receptors and triggers a response.
fundamental metabolite  Any metabolite produced by all living cells.
EC 2.1.2.1 (glycine hydroxymethyltransferase) inhibitor  An EC 2.1.2.* (hydroxymethyl-, formyl- and related transferases) inhibitor that interferes with the action of glycine hydroxymethyltransferase (EC 2.1.2.1).
neurotransmitter  An endogenous compound that is used to transmit information across the synapse between a neuron and another cell.
micronutrient  Any nutrient required in small quantities by organisms throughout their life in order to orchestrate a range of physiological functions.
Applications:
NMDA receptor agonist  An excitatory amino acid agonist which binds to NMDA receptors and triggers a response.
nutraceutical  A product in capsule, tablet or liquid form that provide essential nutrients, such as a vitamin, an essential mineral, a protein, an herb, or similar nutritional substance.
hepatoprotective agent  Any compound that is able to prevent damage to the liver.
ChEBI Ontology
Outgoing Relation(s)
glycine (CHEBI:15428) has role EC 2.1.2.1 (glycine hydroxymethyltransferase) inhibitor (CHEBI:64570)
glycine (CHEBI:15428) has role fundamental metabolite (CHEBI:78675)
glycine (CHEBI:15428) has role hepatoprotective agent (CHEBI:62868)
glycine (CHEBI:15428) has role micronutrient (CHEBI:27027)
glycine (CHEBI:15428) has role neurotransmitter (CHEBI:25512)
glycine (CHEBI:15428) has role NMDA receptor agonist (CHEBI:64571)
glycine (CHEBI:15428) has role nutraceutical (CHEBI:50733)
glycine (CHEBI:15428) is a proteinogenic amino acid (CHEBI:83813)
glycine (CHEBI:15428) is a serine family amino acid (CHEBI:26650)
glycine (CHEBI:15428) is a α-amino acid (CHEBI:33704)
glycine (CHEBI:15428) is conjugate acid of glycinate (CHEBI:32508)
glycine (CHEBI:15428) is conjugate base of glycinium (CHEBI:32507)
glycine (CHEBI:15428) is tautomer of glycine zwitterion (CHEBI:57305)
Incoming Relation(s)
N-carbamoylglycine (CHEBI:133351) has functional parent glycine (CHEBI:15428)
N-hydroxyglycine (CHEBI:38049) has functional parent glycine (CHEBI:15428)
N-nonanoylglycine (CHEBI:74439) has functional parent glycine (CHEBI:15428)
N-octanoylglycine (CHEBI:74099) has functional parent glycine (CHEBI:15428)
N-purin-6-oylglycine (CHEBI:63087) has functional parent glycine (CHEBI:15428)
N-tridecanoylglycine (CHEBI:74437) has functional parent glycine (CHEBI:15428)
N-tris(hydroxymethyl)methylglycine (CHEBI:39063) has functional parent glycine (CHEBI:15428)
N-undecanoylglycine (CHEBI:74438) has functional parent glycine (CHEBI:15428)
N-vinylacetylglycine (CHEBI:74435) has functional parent glycine (CHEBI:15428)
L-Phe-L-Phe-Gly-L-Leu-L-Met-NH2 (CHEBI:191176) has functional parent glycine (CHEBI:15428)
L-Phe-Gly-L-Leu-L-Met-NH2 (CHEBI:191175) has functional parent glycine (CHEBI:15428)
2,2-dialkylglycine (CHEBI:16228) has functional parent glycine (CHEBI:15428)
3-methylcrotonyl glycine (CHEBI:68499) has functional parent glycine (CHEBI:15428)
4-chloro-L-phenylalanylglycine (CHEBI:194316) has functional parent glycine (CHEBI:15428)
4-hydroxyphenylglycine (CHEBI:50418) has functional parent glycine (CHEBI:15428)
4-nitrophenyl phthalimidoacetate (CHEBI:75058) has functional parent glycine (CHEBI:15428)
Ala-Ala-Gly (CHEBI:73318) has functional parent glycine (CHEBI:15428)
Ala-Asp-Gly (CHEBI:73341) has functional parent glycine (CHEBI:15428)
Ala-Cys-Gly (CHEBI:73345) has functional parent glycine (CHEBI:15428)
Ala-Gly-Ala-Gly (CHEBI:143968) has functional parent glycine (CHEBI:15428)
Ala-Gly-His (CHEBI:73348) has functional parent glycine (CHEBI:15428)
Ala-Gly-Pro (CHEBI:73349) has functional parent glycine (CHEBI:15428)
Ala-Gly-Ser (CHEBI:73350) has functional parent glycine (CHEBI:15428)
Ala-Gly-Tyr (CHEBI:73351) has functional parent glycine (CHEBI:15428)
Ala-Leu-Asp-Gly (CHEBI:73362) has functional parent glycine (CHEBI:15428)
Arg-Asn-Gly-Ser (CHEBI:73399) has functional parent glycine (CHEBI:15428)
Arg-Gly (CHEBI:157792) has functional parent glycine (CHEBI:15428)
Arg-Lys-Cys-Gly (CHEBI:73401) has functional parent glycine (CHEBI:15428)
Asn-Gly (CHEBI:73422) has functional parent glycine (CHEBI:15428)
Asn-Gly-Pro-His (CHEBI:176851) has functional parent glycine (CHEBI:15428)
Asp-Gly (CHEBI:73450) has functional parent glycine (CHEBI:15428)
Asp-Gly-Pro (CHEBI:73291) has functional parent glycine (CHEBI:15428)
Asp-Val-Gly-Pro (CHEBI:73441) has functional parent glycine (CHEBI:15428)
Cys-Asp-Gly (CHEBI:140231) has functional parent glycine (CHEBI:15428)
Cys-Phe-Phe-Gly (CHEBI:73460) has functional parent glycine (CHEBI:15428)
Glu-Arg-Gly (CHEBI:162704) has functional parent glycine (CHEBI:15428)
Glu-Arg-Gly-Met (CHEBI:191942) has functional parent glycine (CHEBI:15428)
Glu-Arg-Gly-Met-Thr (CHEBI:191943) has functional parent glycine (CHEBI:15428)
Glu-Glu-Gly (CHEBI:73494) has functional parent glycine (CHEBI:15428)
Glu-Gly (CHEBI:73505) has functional parent glycine (CHEBI:15428)
Glu-Gly-Arg-chloromethylketone (CHEBI:157651) has functional parent glycine (CHEBI:15428)
Glu-Gly-Trp (CHEBI:73496) has functional parent glycine (CHEBI:15428)
Gly-L-Leu-L-Met-NH2 (CHEBI:191172) has functional parent glycine (CHEBI:15428)
Gly-Ala-Ala (CHEBI:144460) has functional parent glycine (CHEBI:15428)
Gly-Arg-Pro (CHEBI:144473) has functional parent glycine (CHEBI:15428)
Gly-His (CHEBI:73515) has functional parent glycine (CHEBI:15428)
Gly-Hyp (CHEBI:138515) has functional parent glycine (CHEBI:15428)
Gly-Leu (CHEBI:73514) has functional parent glycine (CHEBI:15428)
Gly-Pro (CHEBI:70744) has functional parent glycine (CHEBI:15428)
Gly-Pro-Hyp (CHEBI:74135) has functional parent glycine (CHEBI:15428)
Gly-Ser (CHEBI:73516) has functional parent glycine (CHEBI:15428)
Gly-Tyr (CHEBI:73517) has functional parent glycine (CHEBI:15428)
glycine derivative (CHEBI:24373) has functional parent glycine (CHEBI:15428)
glycyl radical (CHEBI:32721) has functional parent glycine (CHEBI:15428)
glycylglycine (CHEBI:17201) has functional parent glycine (CHEBI:15428)
Leu-Ala-Gly (CHEBI:73526) has functional parent glycine (CHEBI:15428)
Leu-Asp-Gly (CHEBI:73562) has functional parent glycine (CHEBI:15428)
Leu-enkephalin (CHEBI:89656) has functional parent glycine (CHEBI:15428)
Leu-Gly-Pro (CHEBI:6414) has functional parent glycine (CHEBI:15428)
Leu-Gly-Ser (CHEBI:138513) has functional parent glycine (CHEBI:15428)
Leu-Leu-Gly (CHEBI:73568) has functional parent glycine (CHEBI:15428)
Leu-Val-Gly (CHEBI:73577) has functional parent glycine (CHEBI:15428)
Lys-Gly (CHEBI:73604) has functional parent glycine (CHEBI:15428)
Met-enkephalin (CHEBI:6618) has functional parent glycine (CHEBI:15428)
Met-Gly (CHEBI:73611) has functional parent glycine (CHEBI:15428)
N-(2-anilino-2-oxoethyl)-2-methoxybenzamide (CHEBI:109416) has functional parent glycine (CHEBI:15428)
norophthalmic acid (CHEBI:143251) has functional parent glycine (CHEBI:15428)
Phe-Ala-Gly (CHEBI:73628) has functional parent glycine (CHEBI:15428)
Phe-Gly (CHEBI:73635) has functional parent glycine (CHEBI:15428)
poly(glycyl-L-arginine) (CHEBI:142891) has functional parent glycine (CHEBI:15428)
Pro-Trp-Val-Gly (CHEBI:73650) has functional parent glycine (CHEBI:15428)
Pro-Val-Gly-Pro (CHEBI:73649) has functional parent glycine (CHEBI:15428)
pyroglutamylglycine (CHEBI:83067) has functional parent glycine (CHEBI:15428)
salicyluric acid (CHEBI:9008) has functional parent glycine (CHEBI:15428)
Thr-Asp-Gly (CHEBI:73658) has functional parent glycine (CHEBI:15428)
tiglylglycine (CHEBI:73018) has functional parent glycine (CHEBI:15428)
trofinetide (CHEBI:229599) has functional parent glycine (CHEBI:15428)
Trp-Ala-Gly (CHEBI:73691) has functional parent glycine (CHEBI:15428)
Val-Gly (CHEBI:73699) has functional parent glycine (CHEBI:15428)
glycine-13C2,15N (CHEBI:191950) is a glycine (CHEBI:15428)
glycine-d5 (CHEBI:132194) is a glycine (CHEBI:15428)
glycinium (CHEBI:32507) is conjugate acid of glycine (CHEBI:15428)
glycinate (CHEBI:32508) is conjugate base of glycine (CHEBI:15428)
glycine residue (CHEBI:29947) is substituent group from glycine (CHEBI:15428)
glycino group (CHEBI:46738) is substituent group from glycine (CHEBI:15428)
glycyl group (CHEBI:46740) is substituent group from glycine (CHEBI:15428)
glycine zwitterion (CHEBI:57305) is tautomer of glycine (CHEBI:15428)
IUPAC Names 
aminoacetic acid
glycine
Synonyms  Source
GlycineKEGG COMPOUND
Aminoacetic acidKEGG COMPOUND
GlyKEGG COMPOUND
GChEBI
aminoethanoic acidChEBI
aminoethanoic acidJCBN
Manual XrefsDatabases
C00037KEGG COMPOUND
GLYPDBeChem
GlycineWikipedia
D00011KEGG DRUG
DB00145DrugBank
HMDB0000123HMDB
GLYMetaCyc
YMDB00016YMDB
ECMDB00123ECMDB
C00001361KNApSAcK
1319DrugCentral
Registry NumbersSources
Gmelin:1808Gmelin
Reaxys:635782Reaxys
CAS:56-40-6KEGG COMPOUND
CAS:56-40-6ChemIDplus
CAS:56-40-6NIST Chemistry WebBook
Citations