CHEBI:15428 - glycine

ChEBI IDCHEBI:15428
ChEBI Nameglycine
Stars
DefinitionThe simplest (and the only achiral) proteinogenic amino acid, with a hydrogen atom as its side chain.
Secondary ChEBI IDsCHEBI:5460, CHEBI:10792, CHEBI:14344, CHEBI:24368, CHEBI:42964
Last Modified16 April 2024
SubmitterMarcus Ennis
DownloadsMolfile
FormulaC2H5NO2
Net Charge0
Average Mass75.067
Monoisotopic Mass75.03203
SMILESNCC(=O)O
InChIInChI=1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)
InChIKeyDHMQDGOQFOQNFH-UHFFFAOYSA-N
Wikipedia
Species of MetaboliteComponentSourceComments
Chlamydomonas reinhardtii (ncbitaxon:3055) - PubMed (25515814)
Daphnia magna (ncbitaxon:35525) - PubMed (20117838)
Escherichia coli (ncbitaxon:562) - PubMed (21988831)
Homo sapiens (ncbitaxon:9606) - DOI (10.1038/nbt.2488)
Mus musculus (ncbitaxon:10090) - PubMed (19425150) Source: BioModels - MODEL1507180067
Saccharomyces cerevisiae (ncbitaxon:4932) - PubMed (24678285) Source: yeast.sf.net
Roles Classification
Chemical Roles:
Bronsted base  A molecular entity capable of accepting a hydron from a donor (Brønsted acid).
Bronsted acid  A molecular entity capable of donating a hydron to an acceptor (Brønsted base).
Biological Roles:
anti-HSV agent  An antiviral agent that destroys or inhibits the replication of the herpes simplex virus (also known as the human herpes virus).
antiviral agent  A substance that destroys or inhibits replication of viruses.
neurotransmitter  An endogenous compound that is used to transmit information across the synapse between a neuron and another cell.
anti-HIV agent  An antiviral agent that destroys or inhibits the replication of the human immunodeficiency virus.
fundamental metabolite  Any metabolite produced by all living cells.
NMDA receptor agonist  An excitatory amino acid agonist which binds to NMDA receptors and triggers a response.
EC 2.1.2.1 (glycine hydroxymethyltransferase) inhibitor  An EC 2.1.2.* (hydroxymethyl-, formyl- and related transferases) inhibitor that interferes with the action of glycine hydroxymethyltransferase (EC 2.1.2.1).
micronutrient  Any nutrient required in small quantities by organisms throughout their life in order to orchestrate a range of physiological functions.
Applications:
nutraceutical  A product in capsule, tablet or liquid form that provide essential nutrients, such as a vitamin, an essential mineral, a protein, an herb, or similar nutritional substance.
antihypertensive agent  Any drug used in the treatment of acute or chronic vascular hypertension regardless of pharmacological mechanism.
anti-asthmatic agent  Any compound that has anti-asthmatic effects.
NMDA receptor agonist  An excitatory amino acid agonist which binds to NMDA receptors and triggers a response.
hepatoprotective agent  Any compound that is able to prevent damage to the liver.
antipsychotic agent  Antipsychotic drugs are agents that control agitated psychotic behaviour, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect.
ChEBI Ontology
Outgoing Relation(s)
glycine (CHEBI:15428) has role anti-asthmatic agent (CHEBI:65023)
glycine (CHEBI:15428) has role anti-HIV agent (CHEBI:64946)
glycine (CHEBI:15428) has role anti-HSV agent (CHEBI:64952)
glycine (CHEBI:15428) has role antihypertensive agent (CHEBI:35674)
glycine (CHEBI:15428) has role antipsychotic agent (CHEBI:35476)
glycine (CHEBI:15428) has role antiviral agent (CHEBI:22587)
glycine (CHEBI:15428) has role EC 2.1.2.1 (glycine hydroxymethyltransferase) inhibitor (CHEBI:64570)
glycine (CHEBI:15428) has role fundamental metabolite (CHEBI:78675)
glycine (CHEBI:15428) has role hepatoprotective agent (CHEBI:62868)
glycine (CHEBI:15428) has role micronutrient (CHEBI:27027)
glycine (CHEBI:15428) has role neurotransmitter (CHEBI:25512)
glycine (CHEBI:15428) has role NMDA receptor agonist (CHEBI:64571)
glycine (CHEBI:15428) has role nutraceutical (CHEBI:50733)
glycine (CHEBI:15428) is a proteinogenic amino acid (CHEBI:83813)
glycine (CHEBI:15428) is a serine family amino acid (CHEBI:26650)
glycine (CHEBI:15428) is a α-amino acid (CHEBI:33704)
glycine (CHEBI:15428) is conjugate acid of glycinate (CHEBI:32508)
glycine (CHEBI:15428) is conjugate base of glycinium (CHEBI:32507)
glycine (CHEBI:15428) is tautomer of glycine zwitterion (CHEBI:57305)
Incoming Relation(s)
N-carbamoylglycine (CHEBI:133351) has functional parent glycine (CHEBI:15428)
N-hydroxyglycine (CHEBI:38049) has functional parent glycine (CHEBI:15428)
N-nonanoylglycine (CHEBI:74439) has functional parent glycine (CHEBI:15428)
N-octanoylglycine (CHEBI:74099) has functional parent glycine (CHEBI:15428)
N-purin-6-oylglycine (CHEBI:63087) has functional parent glycine (CHEBI:15428)
N-tridecanoylglycine (CHEBI:74437) has functional parent glycine (CHEBI:15428)
N-tris(hydroxymethyl)methylglycine (CHEBI:39063) has functional parent glycine (CHEBI:15428)
N-undecanoylglycine (CHEBI:74438) has functional parent glycine (CHEBI:15428)
N-vinylacetylglycine (CHEBI:74435) has functional parent glycine (CHEBI:15428)
L-Phe-L-Phe-Gly-L-Leu-L-Met-NH2 (CHEBI:191176) has functional parent glycine (CHEBI:15428)
L-Phe-Gly-L-Leu-L-Met-NH2 (CHEBI:191175) has functional parent glycine (CHEBI:15428)
2,2-dialkylglycine (CHEBI:16228) has functional parent glycine (CHEBI:15428)
3-methylcrotonyl glycine (CHEBI:68499) has functional parent glycine (CHEBI:15428)
4-chloro-L-phenylalanylglycine (CHEBI:194316) has functional parent glycine (CHEBI:15428)
4-hydroxyphenylglycine (CHEBI:50418) has functional parent glycine (CHEBI:15428)
4-nitrophenyl phthalimidoacetate (CHEBI:75058) has functional parent glycine (CHEBI:15428)
Ala-Ala-Gly (CHEBI:73318) has functional parent glycine (CHEBI:15428)
Ala-Asp-Gly (CHEBI:73341) has functional parent glycine (CHEBI:15428)
Ala-Cys-Gly (CHEBI:73345) has functional parent glycine (CHEBI:15428)
Ala-Gly-Ala-Gly (CHEBI:143968) has functional parent glycine (CHEBI:15428)
Ala-Gly-His (CHEBI:73348) has functional parent glycine (CHEBI:15428)
Ala-Gly-Pro (CHEBI:73349) has functional parent glycine (CHEBI:15428)
Ala-Gly-Ser (CHEBI:73350) has functional parent glycine (CHEBI:15428)
Ala-Gly-Tyr (CHEBI:73351) has functional parent glycine (CHEBI:15428)
Ala-Leu-Asp-Gly (CHEBI:73362) has functional parent glycine (CHEBI:15428)
Arg-Asn-Gly-Ser (CHEBI:73399) has functional parent glycine (CHEBI:15428)
Arg-Gly (CHEBI:157792) has functional parent glycine (CHEBI:15428)
Arg-Lys-Cys-Gly (CHEBI:73401) has functional parent glycine (CHEBI:15428)
Asn-Gly (CHEBI:73422) has functional parent glycine (CHEBI:15428)
Asn-Gly-Pro-His (CHEBI:176851) has functional parent glycine (CHEBI:15428)
Asp-Gly (CHEBI:73450) has functional parent glycine (CHEBI:15428)
Asp-Gly-Pro (CHEBI:73291) has functional parent glycine (CHEBI:15428)
Asp-Val-Gly-Pro (CHEBI:73441) has functional parent glycine (CHEBI:15428)
Cys-Asp-Gly (CHEBI:140231) has functional parent glycine (CHEBI:15428)
Cys-Phe-Phe-Gly (CHEBI:73460) has functional parent glycine (CHEBI:15428)
Glu-Arg-Gly (CHEBI:162704) has functional parent glycine (CHEBI:15428)
Glu-Arg-Gly-Met (CHEBI:191942) has functional parent glycine (CHEBI:15428)
Glu-Arg-Gly-Met-Thr (CHEBI:191943) has functional parent glycine (CHEBI:15428)
Glu-Glu-Gly (CHEBI:73494) has functional parent glycine (CHEBI:15428)
Glu-Gly (CHEBI:73505) has functional parent glycine (CHEBI:15428)
Glu-Gly-Arg-chloromethylketone (CHEBI:157651) has functional parent glycine (CHEBI:15428)
Glu-Gly-Trp (CHEBI:73496) has functional parent glycine (CHEBI:15428)
Gly-L-Leu-L-Met-NH2 (CHEBI:191172) has functional parent glycine (CHEBI:15428)
Gly-Ala-Ala (CHEBI:144460) has functional parent glycine (CHEBI:15428)
Gly-Arg-Pro (CHEBI:144473) has functional parent glycine (CHEBI:15428)
Gly-His (CHEBI:73515) has functional parent glycine (CHEBI:15428)
Gly-Hyp (CHEBI:138515) has functional parent glycine (CHEBI:15428)
Gly-Leu (CHEBI:73514) has functional parent glycine (CHEBI:15428)
Gly-Pro (CHEBI:70744) has functional parent glycine (CHEBI:15428)
Gly-Pro-Hyp (CHEBI:74135) has functional parent glycine (CHEBI:15428)
Gly-Ser (CHEBI:73516) has functional parent glycine (CHEBI:15428)
Gly-Tyr (CHEBI:73517) has functional parent glycine (CHEBI:15428)
glycine derivative (CHEBI:24373) has functional parent glycine (CHEBI:15428)
glycyl radical (CHEBI:32721) has functional parent glycine (CHEBI:15428)
glycylglycine (CHEBI:17201) has functional parent glycine (CHEBI:15428)
Leu-Ala-Gly (CHEBI:73526) has functional parent glycine (CHEBI:15428)
Leu-Asp-Gly (CHEBI:73562) has functional parent glycine (CHEBI:15428)
Leu-enkephalin (CHEBI:89656) has functional parent glycine (CHEBI:15428)
Leu-Gly-Pro (CHEBI:6414) has functional parent glycine (CHEBI:15428)
Leu-Gly-Ser (CHEBI:138513) has functional parent glycine (CHEBI:15428)
Leu-Leu-Gly (CHEBI:73568) has functional parent glycine (CHEBI:15428)
Leu-Val-Gly (CHEBI:73577) has functional parent glycine (CHEBI:15428)
Lys-Gly (CHEBI:73604) has functional parent glycine (CHEBI:15428)
Met-enkephalin (CHEBI:6618) has functional parent glycine (CHEBI:15428)
Met-Gly (CHEBI:73611) has functional parent glycine (CHEBI:15428)
N-(2-anilino-2-oxoethyl)-2-methoxybenzamide (CHEBI:109416) has functional parent glycine (CHEBI:15428)
norophthalmic acid (CHEBI:143251) has functional parent glycine (CHEBI:15428)
Phe-Ala-Gly (CHEBI:73628) has functional parent glycine (CHEBI:15428)
Phe-Gly (CHEBI:73635) has functional parent glycine (CHEBI:15428)
poly(glycyl-L-arginine) (CHEBI:142891) has functional parent glycine (CHEBI:15428)
Pro-Trp-Val-Gly (CHEBI:73650) has functional parent glycine (CHEBI:15428)
Pro-Val-Gly-Pro (CHEBI:73649) has functional parent glycine (CHEBI:15428)
pyroglutamylglycine (CHEBI:83067) has functional parent glycine (CHEBI:15428)
salicyluric acid (CHEBI:9008) has functional parent glycine (CHEBI:15428)
Thr-Asp-Gly (CHEBI:73658) has functional parent glycine (CHEBI:15428)
tiglylglycine (CHEBI:73018) has functional parent glycine (CHEBI:15428)
trofinetide (CHEBI:229599) has functional parent glycine (CHEBI:15428)
Trp-Ala-Gly (CHEBI:73691) has functional parent glycine (CHEBI:15428)
Val-Gly (CHEBI:73699) has functional parent glycine (CHEBI:15428)
glycine-13C2,15N (CHEBI:191950) is a glycine (CHEBI:15428)
glycine-d5 (CHEBI:132194) is a glycine (CHEBI:15428)
glycinium (CHEBI:32507) is conjugate acid of glycine (CHEBI:15428)
glycinate (CHEBI:32508) is conjugate base of glycine (CHEBI:15428)
glycine residue (CHEBI:29947) is substituent group from glycine (CHEBI:15428)
glycino group (CHEBI:46738) is substituent group from glycine (CHEBI:15428)
glycyl group (CHEBI:46740) is substituent group from glycine (CHEBI:15428)
glycine zwitterion (CHEBI:57305) is tautomer of glycine (CHEBI:15428)
IUPAC Names 
aminoacetic acid
glycine
INN  Source
glicinaWHO MedNet
Synonyms  Source
Aminoacetic acidKEGG COMPOUND
AminoessigsäureChEBI
aminoethanoic acidJCBN
aminoethanoic acidChEBI
FEMA NO. 3287ChEMBL
GChEBI
Manual XrefsDatabases
1319DrugCentral
C00001361KNApSAcK
C00037KEGG COMPOUND
D00011KEGG DRUG
DB00145DrugBank
ECMDB00123ECMDB
GLYMetaCyc
GLYPDBeChem
GlycineWikipedia
HMDB0000123HMDB
YMDB00016YMDB
Registry NumbersSources
Gmelin:1808Gmelin
Reaxys:635782Reaxys
CAS:56-40-6KEGG COMPOUND
CAS:56-40-6NIST Chemistry WebBook
CAS:56-40-6ChemIDplus
Citations