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CHEBI:22333 - alkylating agent

ChEBI IDCHEBI:22333
ChEBI Namealkylating agent
Stars
DefinitionHighly reactive chemical that introduces alkyl radicals into biologically active molecules and thereby prevents their proper functioning. It could be used as an antineoplastic agent, but it might be very toxic, with carcinogenic, mutagenic, teratogenic, and immunosuppressant actions. It could also be used as a component of poison gases.
Last Modified1 October 2025
ChEBI Ontology
Outgoing Relation(s)
alkylating agent (CHEBI:22333) is a mutagen (CHEBI:25435)
Incoming Relation(s)
N-ethyl-N-nitrosourea (CHEBI:23995) has role alkylating agent (CHEBI:22333)
N-methyl-N-nitrosourea (CHEBI:50102) has role alkylating agent (CHEBI:22333)
N-methyl-N'-nitro-N-nitrosoguanidine (CHEBI:21759) has role alkylating agent (CHEBI:22333)
N-tosyl-L-phenylalanyl chloromethyl ketone (CHEBI:9642) has role alkylating agent (CHEBI:22333)
S-(chloromethyl)glutathione (CHEBI:136417) has role alkylating agent (CHEBI:22333)
D-mannitol 1,6-bis(methanesulfonate) (CHEBI:18953) has role alkylating agent (CHEBI:22333)
L-mannitol 1,6-bis(methanesulfonate) (CHEBI:18954) has role alkylating agent (CHEBI:22333)
1,2-dimethylhydrazine (CHEBI:73755) has role alkylating agent (CHEBI:22333)
2-aminoacrylic acid (CHEBI:17123) has role alkylating agent (CHEBI:22333)
2-chloroethyl methanesulfonate (CHEBI:19508) has role alkylating agent (CHEBI:22333)
2-fluoroethyl methanesulfonate (CHEBI:19579) has role alkylating agent (CHEBI:22333)
2,5-bis(2-hydroxyethylamino)-3,6-diaziridinylbenzoquinone (CHEBI:90193) has role alkylating agent (CHEBI:22333)
2,5-bis(aziridin-1-yl)-1,4-benzoquinone (CHEBI:19363) has role alkylating agent (CHEBI:22333)
3-bromopyruvic acid (CHEBI:131461) has role alkylating agent (CHEBI:22333)
4-hydroperoxycyclophosphamide (CHEBI:196991) has role alkylating agent (CHEBI:22333)
4-hydroxycyclophosphamide (CHEBI:1864) has role alkylating agent (CHEBI:22333)
acrylamide (CHEBI:28619) has role alkylating agent (CHEBI:22333)
anthramycin (CHEBI:40699) has role alkylating agent (CHEBI:22333)
apholate (CHEBI:33111) has role alkylating agent (CHEBI:22333)
aziridine (CHEBI:30969) has role alkylating agent (CHEBI:22333)
bis(2-chloroethyl) sulfide (CHEBI:25434) has role alkylating agent (CHEBI:22333)
bis(chloromethyl) ether (CHEBI:82270) has role alkylating agent (CHEBI:22333)
bromoethane (CHEBI:47232) has role alkylating agent (CHEBI:22333)
busulfan (CHEBI:28901) has role alkylating agent (CHEBI:22333)
carmustine (CHEBI:3423) has role alkylating agent (CHEBI:22333)
chlorambucil (CHEBI:28830) has role alkylating agent (CHEBI:22333)
chloroacetic acid (CHEBI:27869) has role alkylating agent (CHEBI:22333)
colibactin (CHEBI:156303) has role alkylating agent (CHEBI:22333)
cyclophosphamide (CHEBI:4027) has role alkylating agent (CHEBI:22333)
cyclophosphamide hydrate (CHEBI:4026) has role alkylating agent (CHEBI:22333)
dacarbazine (CHEBI:4305) has role alkylating agent (CHEBI:22333)
diaziquone (CHEBI:90185) has role alkylating agent (CHEBI:22333)
diazomethane (CHEBI:73716) has role alkylating agent (CHEBI:22333)
diethyl sulfate (CHEBI:34699) has role alkylating agent (CHEBI:22333)
dimethyl sulfate (CHEBI:59050) has role alkylating agent (CHEBI:22333)
dimethyl sulfoxide (CHEBI:28262) has role alkylating agent (CHEBI:22333)
dimethylmyleran (CHEBI:67107) has role alkylating agent (CHEBI:22333)
esperamicin A1 (CHEBI:53273) has role alkylating agent (CHEBI:22333)
estramustine (CHEBI:4868) has role alkylating agent (CHEBI:22333)
etanidazole (CHEBI:75473) has role alkylating agent (CHEBI:22333)
ethyl methanesulfonate (CHEBI:23994) has role alkylating agent (CHEBI:22333)
evofosfamide (CHEBI:231678) has role alkylating agent (CHEBI:22333)
fotemustine (CHEBI:131848) has role alkylating agent (CHEBI:22333)
hex-3-yne-2,5-diyl bis(methanesulfonate) (CHEBI:18935) has role alkylating agent (CHEBI:22333)
hexane-2,5-diyl bis(methanesulfonate) (CHEBI:18934) has role alkylating agent (CHEBI:22333)
hycanthone mesylate (CHEBI:24624) has role alkylating agent (CHEBI:22333)
ifosfamide (CHEBI:5864) has role alkylating agent (CHEBI:22333)
iodoacetic acid (CHEBI:74571) has role alkylating agent (CHEBI:22333)
lomustine (CHEBI:6520) has role alkylating agent (CHEBI:22333)
mechlorethamine (CHEBI:28925) has role alkylating agent (CHEBI:22333)
melphalan (CHEBI:28876) has role alkylating agent (CHEBI:22333)
methyl methanesulfonate (CHEBI:25255) has role alkylating agent (CHEBI:22333)
mitomycin A (CHEBI:85412) has role alkylating agent (CHEBI:22333)
mitomycin C (CHEBI:27504) has role alkylating agent (CHEBI:22333)
MTIC (CHEBI:72568) has role alkylating agent (CHEBI:22333)
nimustine (CHEBI:75270) has role alkylating agent (CHEBI:22333)
nitrogen mustard (CHEBI:37598) has role alkylating agent (CHEBI:22333)
pipobroman (CHEBI:8242) has role alkylating agent (CHEBI:22333)
PM00104 (CHEBI:235523) has role alkylating agent (CHEBI:22333)
semustine (CHEBI:6863) has role alkylating agent (CHEBI:22333)
temozolomide (CHEBI:72564) has role alkylating agent (CHEBI:22333)
tilimycin (CHEBI:156293) has role alkylating agent (CHEBI:22333)
tomaymycin (CHEBI:157681) has role alkylating agent (CHEBI:22333)
trabectedin (CHEBI:84050) has role alkylating agent (CHEBI:22333)
tretamine (CHEBI:27919) has role alkylating agent (CHEBI:22333)
triaziquone (CHEBI:27090) has role alkylating agent (CHEBI:22333)
trimethyl phosphite (CHEBI:183313) has role alkylating agent (CHEBI:22333)