EMBL-EBI | Chemical Biology | ChEBI
Example searches: iron*, InChI=1S/CH4O/c1-2/h2H,1H3, caffeine | Advanced Search
CHEBI:4026 - cyclophosphamide hydrate
| Formula | C7H15Cl2N2O2P.H2O |
| Net Charge | 0 |
| Average Mass | 279.104 |
| Monoisotopic Mass | 278.03538 |
| SMILES | O.O=P1(N(CCCl)CCCl)NCCCO1 |
| InChI | InChI=1S/C7H15Cl2N2O2P.H2O/c8-2-5-11(6-3-9)14(12)10-4-1-7-13-14;/h1-7H2,(H,10,12);1H2 |
| InChIKey | PWOQRKCAHTVFLB-UHFFFAOYSA-N |
| Roles Classification |
|---|
| Biological Roles: | alkylating agent Highly reactive chemical that introduces alkyl radicals into biologically active molecules and thereby prevents their proper functioning. It could be used as an antineoplastic agent, but it might be very toxic, with carcinogenic, mutagenic, teratogenic, and immunosuppressant actions. It could also be used as a component of poison gases. carcinogenic agent A role played by a chemical compound which is known to induce a process of carcinogenesis by corrupting normal cellular pathways, leading to the acquistion of tumoral capabilities. immunosuppressive agent An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response. |
| Applications: | antineoplastic agent A substance that inhibits or prevents the proliferation of neoplasms. immunosuppressive agent An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| cyclophosphamide hydrate (CHEBI:4026) has part cyclophosphamide (CHEBI:4027) |
| cyclophosphamide hydrate (CHEBI:4026) has role alkylating agent (CHEBI:22333) |
| cyclophosphamide hydrate (CHEBI:4026) has role antineoplastic agent (CHEBI:35610) |
| cyclophosphamide hydrate (CHEBI:4026) has role carcinogenic agent (CHEBI:50903) |
| cyclophosphamide hydrate (CHEBI:4026) has role immunosuppressive agent (CHEBI:35705) |
| cyclophosphamide hydrate (CHEBI:4026) is a hydrate (CHEBI:35505) |
| IUPAC Names |
|---|
| N,N-bis(2-chloroethyl)-1,3,2-oxazaphosphinan-2-amine 2-oxide hydrate |
| N,N-bis(2-chloroethyl)-1,3,2-oxazaphosphinan-2-amine 2-oxide—water (1/1) |
| INN | Source |
|---|---|
| cyclophosphamide | ChemIDplus |
| Synonyms | Source |
|---|---|
| Cyclophosphamide | KEGG DRUG |
| (±)-2-(Bis(2-chloroethyl)amino)tetrahydro-2H-1,3,2-oxazaphosphorine 2-oxide monohydrate | ChemIDplus |
| (Bis(chloro-2-ethyl)amino)-2-tetrahydro-3,4,5,6-oxazaphosphorine-1,3,2-oxide-2 monohydrate | ChemIDplus |
| 1-Bis(2-chloroethyl)amino-1-oxo-2-aza-5-oxaphosphoridine monohydrate | ChemIDplus |
| 2-(Bis(2-chloroethyl)amino)-1-oxa-3-aza-2-phosphocyclohexane 2-oxide monohydrate | ChemIDplus |
| 2-(Di(2-chloroethyl)amino)-1-oxa-3-aza-2-phosphacyclohexane-2-oxide monohydrate | ChemIDplus |