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CHEBI:37598 - nitrogen mustard

ChEBI IDCHEBI:37598
ChEBI Namenitrogen mustard
Stars
DefinitionCompounds having two β-haloalkyl groups bound to a nitrogen atom, as in (X‒CH2‒CH2)2NR.
Last Modified13 June 2014
SubmitterKirill Degtyarenko
Wikipedia
Roles Classification
Biological Role:
alkylating agent  Highly reactive chemical that introduces alkyl radicals into biologically active molecules and thereby prevents their proper functioning. It could be used as an antineoplastic agent, but it might be very toxic, with carcinogenic, mutagenic, teratogenic, and immunosuppressant actions. It could also be used as a component of poison gases.
ChEBI Ontology
Outgoing Relation(s)
nitrogen mustard (CHEBI:37598) has role alkylating agent (CHEBI:22333)
nitrogen mustard (CHEBI:37598) is a organonitrogen compound (CHEBI:35352)
Incoming Relation(s)
2-({4-[bis(2-chloroethyl)amino]-2-methylphenyl}diazenyl)benzoic acid (CHEBI:34193) is a nitrogen mustard (CHEBI:37598)
3,4-dibromopyrrole-2,5-dione (CHEBI:210335) is a nitrogen mustard (CHEBI:37598)
3,4-Dichloro-5-hydroxy-2H-pyrrol-2-one (CHEBI:184738) is a nitrogen mustard (CHEBI:37598)
4-hydroperoxycyclophosphamide (CHEBI:196991) is a nitrogen mustard (CHEBI:37598)
4-hydroxycyclophosphamide (CHEBI:1864) is a nitrogen mustard (CHEBI:37598)
4-Ketocyclophosphamide (CHEBI:1887) is a nitrogen mustard (CHEBI:37598)
5-[bis(2-chloroethyl)amino]uracil (CHEBI:9884) is a nitrogen mustard (CHEBI:37598)
Alcophosphamide (CHEBI:80559) is a nitrogen mustard (CHEBI:37598)
Aldophosphamide (CHEBI:2560) is a nitrogen mustard (CHEBI:37598)
bis(2-chloroethyl)amine (CHEBI:37599) is a nitrogen mustard (CHEBI:37598)
Carboxyphosphamide (CHEBI:3410) is a nitrogen mustard (CHEBI:37598)
chlorambucil (CHEBI:28830) is a nitrogen mustard (CHEBI:37598)
cyclophosphamide (CHEBI:4027) is a nitrogen mustard (CHEBI:37598)
ifosfamides (CHEBI:55369) is a nitrogen mustard (CHEBI:37598)
mechlorethamine (CHEBI:28925) is a nitrogen mustard (CHEBI:37598)
melphalan (CHEBI:28876) is a nitrogen mustard (CHEBI:37598)
N-[[4-[bis(2-chloroethyl)amino]-2-methylphenyl]methylideneamino]-2-furancarboxamide (CHEBI:116496) is a nitrogen mustard (CHEBI:37598)
Nitrogen mustard N-oxide (CHEBI:82354) is a nitrogen mustard (CHEBI:37598)
Nitrogen mustard N-oxide hydrochloride (CHEBI:31913) is a nitrogen mustard (CHEBI:37598)
perfosfamide (CHEBI:135223) is a nitrogen mustard (CHEBI:37598)
phosphoramide mustard (CHEBI:8163) is a nitrogen mustard (CHEBI:37598)
quinacrine mustard (CHEBI:37595) is a nitrogen mustard (CHEBI:37598)
IUPAC Name 
nitrogen mustards
Synonyms  Source
nitrogen mustardsChEBI
nitrogen mustard compoundsChEBI
nitrogen mustard compoundChEBI
Manual XrefsDatabases
Nitrogen_mustardWikipedia