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CHEBI:8242 - pipobroman

ChEBI IDCHEBI:8242
ChEBI Namepipobroman
Stars
DefinitionAn N-acylpiperazine that is piperazine in which each of the nitrogens has been acylated by a 3-bromopropionoyl group. An anti-cancer drug.
Last Modified22 June 2018
DownloadsMolfile
FormulaC10H16Br2N2O2
Net Charge0
Average Mass356.058
Monoisotopic Mass353.95785
SMILESO=C(CCBr)N1CCN(C(=O)CCBr)CC1
InChIInChI=1S/C10H16Br2N2O2/c11-3-1-9(15)13-5-7-14(8-6-13)10(16)2-4-12/h1-8H2
InChIKeyNJBFOOCLYDNZJN-UHFFFAOYSA-N
Wikipedia
Roles Classification
Biological Role:
alkylating agent  Highly reactive chemical that introduces alkyl radicals into biologically active molecules and thereby prevents their proper functioning. It could be used as an antineoplastic agent, but it might be very toxic, with carcinogenic, mutagenic, teratogenic, and immunosuppressant actions. It could also be used as a component of poison gases.
Application:
antineoplastic agent  A substance that inhibits or prevents the proliferation of neoplasms.
ChEBI Ontology
Outgoing Relation(s)
pipobroman (CHEBI:8242) has role alkylating agent (CHEBI:22333)
pipobroman (CHEBI:8242) has role antineoplastic agent (CHEBI:35610)
pipobroman (CHEBI:8242) is a N-acylpiperazine (CHEBI:46844)
pipobroman (CHEBI:8242) is a organobromine compound (CHEBI:37141)
pipobroman (CHEBI:8242) is a tertiary carboxamide (CHEBI:140326)
IUPAC Name 
1,1'-piperazine-1,4-diylbis(3-bromopropan-1-one)
INNs  Source
pipobromanChemIDplus
pipobromanumChemIDplus
Synonyms  Source
A-8103ChemIDplus
A 8103ChEBI
1,4-bis(3-bromopropionyl)piperazineNIST Chemistry WebBook
N,N-bis-(3-bromopropionyl)-piperazineNIST Chemistry WebBook
Brand Names  Source
AmedelDrugCentral
VercyteDrugCentral
Manual XrefsDatabases
C07362KEGG COMPOUND
D00467KEGG DRUG
2192DrugCentral
PipobromanWikipedia
HMDB0014381HMDB
DE1138781Patent
DB00236DrugBank
Registry NumbersSources
CAS:54-91-1NIST Chemistry WebBook
Citations