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CHEBI:16914 - salicylic acid
| Formula | C7H6O3 |
| Net Charge | 0 |
| Average Mass | 138.122 |
| Monoisotopic Mass | 138.03169 |
| SMILES | O=C(O)c1ccccc1O |
| InChI | InChI=1S/C7H6O3/c8-6-4-2-1-3-5(6)7(9)10/h1-4,8H,(H,9,10) |
| InChIKey | YGSDEFSMJLZEOE-UHFFFAOYSA-N |
| Wikipedia |
|---|
| Species of Metabolite | Component | Source | Comments |
|---|---|---|---|
| Chlamydomonas reinhardtii (ncbitaxon:3055) | - | PubMed (25515814) | |
| Cordyceps sinensis (ncbitaxon:72228) | mycelium (BTO:0001436) | PubMed (21848266) | Ethanolic extract of dried mycelia |
| Roles Classification |
|---|
| Chemical Role: | Bronsted acid A molecular entity capable of donating a hydron to an acceptor (Brønsted base). |
| Biological Roles: | algal metabolite Any eukaryotic metabolite produced during a metabolic reaction in algae including unicellular organisms like chlorella and diatoms to multicellular organisms like giant kelps and brown algae. analgesic An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms. plant metabolite Any eukaryotic metabolite produced during a metabolic reaction in plants, the kingdom that include flowering plants, conifers and other gymnosperms. EC 1.11.1.11 (L-ascorbate peroxidase) inhibitor An EC 1.11.1.* (peroxidases) inhibitor that inhibits the action of L-ascorbate peroxidase (EC 1.11.1.11). antifungal agent An antimicrobial agent that destroys fungi by suppressing their ability to grow or reproduce. plant hormone A plant growth regulator that modulates the formation of stems, leaves and flowers, as well as the development and ripening of fruit. The term includes endogenous and non-endogenous compounds (e.g. active compounds produced by bacteria on the leaf surface) as well as semi-synthetic and fully synthetic compounds. |
| Applications: | cardiovascular drug A drug that affects the rate or intensity of cardiac contraction, blood vessel diameter or blood volume. antiinfective agent A substance used in the prophylaxis or therapy of infectious diseases. antineoplastic agent A substance that inhibits or prevents the proliferation of neoplasms. dermatologic drug A drug used to treat or prevent skin disorders or for the routine care of skin. keratolytic drug A drug that softens, separates, and causes desquamation of the cornified epithelium or horny layer of skin. Keratolytic drugs are used to expose mycelia of infecting fungi or to treat corns, warts, and certain other skin diseases. analgesic An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms. anticoagulant An agent that prevents blood clotting. antipsoriatic A drug used to treat psoriasis. anti-inflammatory agent Any compound that has anti-inflammatory effects. ophthalmology drug Any compound used for the treatment of eye conditions or eye diseases. antidote Any protective agent counteracting or neutralizing the action of poisons. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| salicylic acid (CHEBI:16914) has role algal metabolite (CHEBI:84735) |
| salicylic acid (CHEBI:16914) has role analgesic (CHEBI:35480) |
| salicylic acid (CHEBI:16914) has role anti-inflammatory agent (CHEBI:67079) |
| salicylic acid (CHEBI:16914) has role anticoagulant (CHEBI:50249) |
| salicylic acid (CHEBI:16914) has role antidote (CHEBI:50247) |
| salicylic acid (CHEBI:16914) has role antifungal agent (CHEBI:35718) |
| salicylic acid (CHEBI:16914) has role antiinfective agent (CHEBI:35441) |
| salicylic acid (CHEBI:16914) has role antineoplastic agent (CHEBI:35610) |
| salicylic acid (CHEBI:16914) has role antipsoriatic (CHEBI:50748) |
| salicylic acid (CHEBI:16914) has role cardiovascular drug (CHEBI:35554) |
| salicylic acid (CHEBI:16914) has role dermatologic drug (CHEBI:50177) |
| salicylic acid (CHEBI:16914) has role EC 1.11.1.11 (L-ascorbate peroxidase) inhibitor (CHEBI:73181) |
| salicylic acid (CHEBI:16914) has role keratolytic drug (CHEBI:50176) |
| salicylic acid (CHEBI:16914) has role ophthalmology drug (CHEBI:66981) |
| salicylic acid (CHEBI:16914) has role plant hormone (CHEBI:37848) |
| salicylic acid (CHEBI:16914) has role plant metabolite (CHEBI:76924) |
| salicylic acid (CHEBI:16914) is a monohydroxybenzoic acid (CHEBI:25389) |
| salicylic acid (CHEBI:16914) is conjugate acid of salicylate (CHEBI:30762) |
| Incoming Relation(s) |
| O-(S-2-hydroxybenzoylpantetheine-4'-phosphoryl)-L-serine residue (CHEBI:86462) has functional parent salicylic acid (CHEBI:16914) |
| D-glucosyl salicylate (CHEBI:133564) has functional parent salicylic acid (CHEBI:16914) |
| 1-salicylate glucuronide (CHEBI:73961) has functional parent salicylic acid (CHEBI:16914) |
| 2-(D-glucosyloxy)benzoic acid (CHEBI:87766) has functional parent salicylic acid (CHEBI:16914) |
| 2-[[2-[(2-hydroxyphenyl)-oxomethoxy]-1-oxoethyl]amino]-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxylic acid methyl ester (CHEBI:121777) has functional parent salicylic acid (CHEBI:16914) |
| 2-hydroxy-3-methylbenzoic acid (3-cyano-4-imino-2-oxopentyl) ester (CHEBI:112747) has functional parent salicylic acid (CHEBI:16914) |
| 2-hydroxy-4-methylbenzoic acid [2-(2-chloroanilino)-2-oxoethyl] ester (CHEBI:116485) has functional parent salicylic acid (CHEBI:16914) |
| 2-Hydroxy-4-trifluoromethyl benzoic acid (CHEBI:174020) has functional parent salicylic acid (CHEBI:16914) |
| 2-hydroxy-5-[(4-methoxyphenyl)sulfamoyl]benzoic acid [2-[1-(3-bicyclo[2.2.1]heptanyl)ethylamino]-2-oxoethyl] ester (CHEBI:121984) has functional parent salicylic acid (CHEBI:16914) |
| 2-hydroxy-6-(12-oxoheptadecyl)benzoic acid (CHEBI:211672) has functional parent salicylic acid (CHEBI:16914) |
| 2-hydroxy-6-(12-oxopentadecyl)benzoic acid (CHEBI:211679) has functional parent salicylic acid (CHEBI:16914) |
| 2-Hydroxy-6-(8-tridecenyl)benzoic acid (CHEBI:192876) has functional parent salicylic acid (CHEBI:16914) |
| 2-Hydroxy-6-(8,11,14-pentadecatrienyl)benzoic acid (CHEBI:174627) has functional parent salicylic acid (CHEBI:16914) |
| 2-hydroxy-6-[(8Z,11Z)-pentadeca-8,11,14-trien-1-yl]benzoic acid (CHEBI:183726) has functional parent salicylic acid (CHEBI:16914) |
| 2-Hydroxy-6-pentadeca-8,11,14-trienyl benzoic acid (CHEBI:181219) has functional parent salicylic acid (CHEBI:16914) |
| 2-Hydroxy-6-tridecylbenzoic acid (CHEBI:175101) has functional parent salicylic acid (CHEBI:16914) |
| 2-hydroxybenzoic acid (3,3,5-trimethylcyclohexyl) ester (CHEBI:91642) has functional parent salicylic acid (CHEBI:16914) |
| 2-hydroxybenzoic acid [2-(2-ethoxyanilino)-2-oxo-1-phenylethyl] ester (CHEBI:114677) has functional parent salicylic acid (CHEBI:16914) |
| 2-hydroxybenzoic acid [2-[[(1-methyl-2-pyrrolyl)-oxomethyl]amino]-2-oxoethyl] ester (CHEBI:108199) has functional parent salicylic acid (CHEBI:16914) |
| 2-hydroxybenzoyl-AMP (CHEBI:86457) has functional parent salicylic acid (CHEBI:16914) |
| 2-hydroxybenzoyl-CoA (CHEBI:32587) has functional parent salicylic acid (CHEBI:16914) |
| 2-hydroxyethyl salicylate (CHEBI:86541) has functional parent salicylic acid (CHEBI:16914) |
| 2,6-dihydroxy-4-[(2R)-2-hydroxyheptyl]benzoic acid (CHEBI:213766) has functional parent salicylic acid (CHEBI:16914) |
| 3-allyl-2-hydroxybenzoic acid (CHEBI:167783) has functional parent salicylic acid (CHEBI:16914) |
| 3-bromo-5-chloro-2,6-dihydroxybenzoic acid* (CHEBI:233864) has functional parent salicylic acid (CHEBI:16914) |
| 3-formylsalicylic acid (CHEBI:34334) has functional parent salicylic acid (CHEBI:16914) |
| 3-Hydroxyphthalic acid (CHEBI:204117) has functional parent salicylic acid (CHEBI:16914) |
| 3-methylsalicylic acid (CHEBI:20141) has functional parent salicylic acid (CHEBI:16914) |
| 3,5-dinitrosalicylic acid (CHEBI:53648) has functional parent salicylic acid (CHEBI:16914) |
| 3,6-dimethylsalicylic acid (CHEBI:70733) has functional parent salicylic acid (CHEBI:16914) |
| 4-[amino(carboxy)methyl]-2-hydroxybenzoic acid (CHEBI:93904) has functional parent salicylic acid (CHEBI:16914) |
| 4-acetamidosalicylic acid (CHEBI:63816) has functional parent salicylic acid (CHEBI:16914) |
| 4-aminosalicylic acid (CHEBI:27565) has functional parent salicylic acid (CHEBI:16914) |
| 4-formylsalicylic acid (CHEBI:20367) has functional parent salicylic acid (CHEBI:16914) |
| 4-hydroxymethylsalicylic acid (CHEBI:20415) has functional parent salicylic acid (CHEBI:16914) |
| 4-methylsalicylic acid (CHEBI:20450) has functional parent salicylic acid (CHEBI:16914) |
| 4R,5R,6S-Trihydroxy-2-hydroxymethyl-2-cyclohexen-1-one 6-(2-hydroxy-6-methylbenzoate) (CHEBI:174940) has functional parent salicylic acid (CHEBI:16914) |
| 5-(diethylsulfamoyl)-2-hydroxybenzoic acid [2-oxo-2-[4-(trifluoromethoxy)anilino]ethyl] ester (CHEBI:123403) has functional parent salicylic acid (CHEBI:16914) |
| 5-[amino(carboxy)methyl]-2-hydroxybenzoic acid (CHEBI:93840) has functional parent salicylic acid (CHEBI:16914) |
| 5-formylsalicylic acid (CHEBI:137371) has functional parent salicylic acid (CHEBI:16914) |
| 5-nitrososalicylic acid (CHEBI:143303) has functional parent salicylic acid (CHEBI:16914) |
| 6-((8Z,11Z,14Z)-heptadeca-8,11,14-trien-1-yl)salicylic acid (CHEBI:186627) has functional parent salicylic acid (CHEBI:16914) |
| 6-((Z)-pentadec-10-en-1-yl)salicylic acid (CHEBI:186923) has functional parent salicylic acid (CHEBI:16914) |
| 6-((Z)-pentadec-8-en-1-yl)salicylic acid (CHEBI:193466) has functional parent salicylic acid (CHEBI:16914) |
| 6-formylsalicylic acid (CHEBI:208549) has functional parent salicylic acid (CHEBI:16914) |
| 6-hydroxy platensimycin A1 methyl ester (CHEBI:68270) has functional parent salicylic acid (CHEBI:16914) |
| 6-methylsalicylic acid (CHEBI:17637) has functional parent salicylic acid (CHEBI:16914) |
| acetylsalicylic acid (CHEBI:15365) has functional parent salicylic acid (CHEBI:16914) |
| aminosalicylate calcium (CHEBI:751730) has functional parent salicylic acid (CHEBI:16914) |
| aminosalicylate potassium (CHEBI:749282) has functional parent salicylic acid (CHEBI:16914) |
| aminosalicylate sodium (CHEBI:750448) has functional parent salicylic acid (CHEBI:16914) |
| ammonium salicylate (CHEBI:751738) has functional parent salicylic acid (CHEBI:16914) |
| Ampelomin G (CHEBI:223031) has functional parent salicylic acid (CHEBI:16914) |
| anacardic acid (CHEBI:2696) has functional parent salicylic acid (CHEBI:16914) |
| anacardic acid diene (CHEBI:233992) has functional parent salicylic acid (CHEBI:16914) |
| Antibiotic SB 202742 (CHEBI:174937) has functional parent salicylic acid (CHEBI:16914) |
| Benzyl salicylate (CHEBI:165211) has functional parent salicylic acid (CHEBI:16914) |
| biphenamine hydrochloride (CHEBI:752077) has functional parent salicylic acid (CHEBI:16914) |
| Butyl salicylate (CHEBI:173949) has functional parent salicylic acid (CHEBI:16914) |
| Chloropupukeananin (CHEBI:216291) has functional parent salicylic acid (CHEBI:16914) |
| Chloropupukeanone A (CHEBI:207995) has functional parent salicylic acid (CHEBI:16914) |
| Choline salicylate (CHEBI:3668) has functional parent salicylic acid (CHEBI:16914) |
| crelosidenib gentisate (CHEBI:760303) has functional parent salicylic acid (CHEBI:16914) |
| detanosal (CHEBI:751852) has functional parent salicylic acid (CHEBI:16914) |
| diflunisal (CHEBI:39669) has functional parent salicylic acid (CHEBI:16914) |
| Ethyl 4-ethoxy-2-hydroxy-3,6-dimethylbenzoate (CHEBI:214582) has functional parent salicylic acid (CHEBI:16914) |
| Ethylhexyl salicylate (CHEBI:88639) has functional parent salicylic acid (CHEBI:16914) |
| Gentisic acid sodium (CHEBI:189437) has functional parent salicylic acid (CHEBI:16914) |
| Gibbestatin B (CHEBI:220560) has functional parent salicylic acid (CHEBI:16914) |
| Ginkgoic acid (CHEBI:5354) has functional parent salicylic acid (CHEBI:16914) |
| Ginkgolic Acid C17-1 (CHEBI:228873) has functional parent salicylic acid (CHEBI:16914) |
| Glycerol 1-hydroxy-2,5-dimethyl benzoate (CHEBI:227951) has functional parent salicylic acid (CHEBI:16914) |
| hydroxyprocaine (CHEBI:751940) has functional parent salicylic acid (CHEBI:16914) |
| hydroxytetracaine (CHEBI:135162) has functional parent salicylic acid (CHEBI:16914) |
| imidazole salicylate (CHEBI:751053) has functional parent salicylic acid (CHEBI:16914) |
| Isoamyl salicylate (CHEBI:173601) has functional parent salicylic acid (CHEBI:16914) |
| Isobutyl salicylate (CHEBI:173947) has functional parent salicylic acid (CHEBI:16914) |
| isopropyl salicylate (CHEBI:38703) has functional parent salicylic acid (CHEBI:16914) |
| menthyl salicylate (CHEBI:135976) has functional parent salicylic acid (CHEBI:16914) |
| mesalamine (CHEBI:6775) has functional parent salicylic acid (CHEBI:16914) |
| Methyl 2-(10-heptadecenyl)-6-hydroxybenzoate (CHEBI:169431) has functional parent salicylic acid (CHEBI:16914) |
| Methyl 2,6-dihydroxybenzoate (CHEBI:192874) has functional parent salicylic acid (CHEBI:16914) |
| Methyl 4-(4,6-dihydroxy-5-methoxy-2,5-dimethyl-3-oxocyclohexen-1-yl)oxy-2-hydroxy-3,6-dimethylbenzoate (CHEBI:181274) has functional parent salicylic acid (CHEBI:16914) |
| Methyl 5-chloro-2-hydroxybenzoate (CHEBI:194865) has functional parent salicylic acid (CHEBI:16914) |
| methyl salicylate (CHEBI:31832) has functional parent salicylic acid (CHEBI:16914) |
| Nabscebetain A (CHEBI:206787) has functional parent salicylic acid (CHEBI:16914) |
| Nabscebetain B (CHEBI:206794) has functional parent salicylic acid (CHEBI:16914) |
| olsalazine (CHEBI:7770) has functional parent salicylic acid (CHEBI:16914) |
| Phenethyl salicylate (CHEBI:173744) has functional parent salicylic acid (CHEBI:16914) |
| phenyl salicylate (CHEBI:34918) has functional parent salicylic acid (CHEBI:16914) |
| Phomone A (CHEBI:205846) has functional parent salicylic acid (CHEBI:16914) |
| Pleoniol C (CHEBI:214724) has functional parent salicylic acid (CHEBI:16914) |
| potassium salicylate (CHEBI:755811) has functional parent salicylic acid (CHEBI:16914) |
| promysalin (CHEBI:171658) has functional parent salicylic acid (CHEBI:16914) |
| Roccellatol (CHEBI:220613) has functional parent salicylic acid (CHEBI:16914) |
| Salaceyin A (CHEBI:224587) has functional parent salicylic acid (CHEBI:16914) |
| Salaceyin B (CHEBI:220151) has functional parent salicylic acid (CHEBI:16914) |
| salcolex (CHEBI:752486) has functional parent salicylic acid (CHEBI:16914) |
| salicylamides (CHEBI:53443) has functional parent salicylic acid (CHEBI:16914) |
| salicylate meglumine (CHEBI:752666) has functional parent salicylic acid (CHEBI:16914) |
| salicylic acid-d4 (CHEBI:178057) has functional parent salicylic acid (CHEBI:16914) |
| salsalate (CHEBI:9014) has functional parent salicylic acid (CHEBI:16914) |
| strontium salicylate (CHEBI:752537) has functional parent salicylic acid (CHEBI:16914) |
| sulprosal (CHEBI:752711) has functional parent salicylic acid (CHEBI:16914) |
| trolamine salicylate (CHEBI:752545) has functional parent salicylic acid (CHEBI:16914) |
| valerylsalicylic acid (CHEBI:78250) has functional parent salicylic acid (CHEBI:16914) |
| salicylate (CHEBI:30762) is conjugate base of salicylic acid (CHEBI:16914) |
| 2-hydroxybenzoyl group (CHEBI:60335) is substituent group from salicylic acid (CHEBI:16914) |
| IUPAC Name |
|---|
| 2-hydroxybenzoic acid |
| Synonyms | Source |
|---|---|
| 2-carboxyphenol | NIST Chemistry WebBook |
| 2-HYDROXYBENZOIC ACID | PDBeChem |
| o-carboxyphenol | NIST Chemistry WebBook |
| o-hydroxybenzoic acid | NIST Chemistry WebBook |
| FEMA NO. 3985 | ChEMBL |
| K-557 | ChEMBL |
| Brand Names | Source |
|---|---|
| Acnisal | ChEMBL |
| Bazuka | ChEMBL |
| Compound v | ChEMBL |
| Cuplex verruca | ChEMBL |
| Duofilm | ChEMBL |
| Edinburgh | ChEMBL |
| Manual Xrefs | Databases |
|---|---|
| 2416 | DrugCentral |
| C00000206 | KNApSAcK |
| C00805 | KEGG COMPOUND |
| CPD-110 | MetaCyc |
| D00097 | KEGG DRUG |
| DB00936 | DrugBank |
| HMDB0001895 | HMDB |
| LSM-4763 | LINCS |
| SAL | PDBeChem |
| Salicylic_Acid | Wikipedia |
| Citations |
|---|