About EMDB
Meet the team
The Electron Microscopy Data Bank (EMDB) team operates out of EMBL-EBI and you can read more about us here.
EMDB history
The EMDB is a public repository for cryogenic-sample Electron Microscopy (cryoEM) volumes and representative tomograms of macromolecular complexes and subcellular structures. It covers a variety of techniques, including single-particle analysis, helical reconstruction, electron tomography, subtomogram averaging, and electron crystallography (for more information, see the EMDB Policies).
EMDB was founded at EMBL-EBI in 2002 under the leadership of Kim Henrick. From 2007, the archive has been operated jointly by EMBL-EBI and the Research Collaboratory for Structural Bioinformatics (RCSB)a. In 2013, the Protein Data Bank Japan (PDBj) also became involved in EMDB. As of the first of January, 2021, EMDB is an archive operated under the aegis of the Worldwide Protein Data Bank (wwPDB), and has also joined that organisation as a full member.
Results of cryo-EM studies are archived in three collaborating archives:
- EMDB stores the processed 3D volumes and tomograms;
- PDB stores any atomic models that have been constructed based on EMDB data;
- EMPIAR stores the raw EM data underpinning the data in EMDB/PDB.
Data for EMDB and PDB can be deposited through the wwPDB deposition and annotation system OneDep.
EMPIAR (Electron Microscopy Public Image Archive) is a companion archive to EMDB, founded at and operated by EMBL-EBI, and with a mirror site at PDBj.
Citing EMDB
Please cite the following publication in your papers and on websites: The wwPDB Consortium, EMDB—the Electron Microscopy Data Bank, Nucleic Acids Research, Volume 52, Issue D1, 5 January 2024, Pages D456–D465, https://doi.org/10.1093/nar/gkad1019
To cite individual entries, please quote the EMDB accession code(s) and cite the original publication(s) in which the entries are described.
EMDB logos and branding should not be used on public-facing websites unless explicit prior permission has been obtained from us. However, if you want to use an EMDB logo in a presentation or report, you can use the images in the following table royalty-free and without the need to obtain prior permission from us.
More information
Please see our FAQ, Policies, description of the EMDB data model, or contact the EMDB helpdesk.
Funding
The work on EMDB at EMBL-EBI has been funded in the past by the European Commission, NIH, UKRI-BBSRC and EMBL-EBI (through the EMBL member states). It is currently funded by the Wellcome Trust and EMBL-EBI.
Quick links
Recent Entries
(Show all)Cryo-EM structure of P. urativorans 70S ribosome after 2h acute stress - State 1: Rotated with E-tRNA/P-tRNA
Structure of human SLC37A4 bound to chlorogenic acid in a lipid nanodisc
Cryo-EM structure of PGT121 Fab and Rhesus macaque Ab4 Fab in complex with HIV-1 Env trimer BG505 SOSIP.664
Cryo-EM structure of PGT121 Fab and Rhesus macaque Ab76 Fab in complex with HIV-1 Env trimer BG505 SOSIP.664
The CryoEM structure of Rhesus macaque 1G3 and PGT121 Fabs in complex with BG505 SOSIP.664
Architecture of human Voltage Dependent Anion Channel 1 in nanodiscs
THE CRYOEM STRUCTURE OF RHESUS MACAQUE 1A8 AND PGT121 FABS IN COMPLEX WITH BG505 SOSIP.664.
Structures of multiple states of the nicotinamide nucleotide transhydrogenase from Escherichia coli
Single-subunit apo Escherichia coli nicotinamide nucleotide transhydrogenase
Single-subunit apo Escherichia coli nicotinamide nucleotide transhydrogenase
Escherichia coli nicotinamide nucleotide transhydrogenase single dIII attached to dII state in the presence of NADPH
Wild-type apo Escherichia coli nicotinamide nucleotide transhydrogenase
Escherichia coli transhydrogenase the dissociated (dI)2 dimer in the presence of both NADPH and NADP+
Structures of multiple states of the nicotinamide nucleotide transhydrogenase from Escherichia coli
Structures of multiple states of the nicotinamide nucleotide transhydrogenase from Escherichia coli
Single-subunit Escherichia coli nicotinamide nucleotide transhydrogenase in the presence of palmitoyl-CoA
Escherichia coli transhydrogenase single dIII attached to dII state in the presence of both NADPH and NADP+
Cryo-EM structure of the Nipah virus RNA-dependent RNA polymerase complex bound to allosteric inhibitor ERDRP-0519
Cryo-EM structure of full-length self-sufficient P450 from Shimazuella soli
Cryo-EM structure of the human measles virus RNA-dependent RNA polymerase complex
Cryo-EM structure of the human measles virus RNA-dependent RNA polymerase
Cryo-EM structure of the human measles virus RNA-dependent RNA polymerase complex bound to viral protein C
Cryo-EM structure of the human measles virus RNA-dependent RNA polymerase bound to allosteric inhibitor ERDRP-0519
Cryo-EM structure of one-heme-missing self-sufficient P450 from Shimazuella soli
Cryo-EM structure of full-length self-sufficient P450 in complex with NADPH from Shimazuella soli
Cryo-EM structure of loop truncated self-sufficient P450 from Shimazuella soli
Structure of the anthrax protective antigen in complex with a potent neutralizing antibody
Cryo-EM structure of the PI3K alpha/KRas complex on POPC/POPS/PIP2 nanodiscs
Cryo-EM structure of the Class 2 PI3K alpha/KRas complex on POPC/POPS nanodiscs
Structure of hTWIK2RM (K2P6.1RM) ion channel without lipid plug in DDM detergent
Structure of hTWIK2RM-R257A (K2P6.1RM-R257A) ion channel with lipid plug in DDM detergent
Structure of hTWIK2RM-R257A (K2P6.1RM-R257A) ion channel without lipid plug in DDM detergent
Structure of hTWIK2RM (K2P6.1RM) ion channel with lipid plug in DDM detergent
Human claudin 18.2 in complex with the Fab fragment of Zolbetuximab
The composite Cryo-EM structure of bacteriophage RAN69 pre-ejectosome-portal complex
Local refinement of the portal region within the bacteriophage RAN69 pre-ejectosome-portal complex
Cryo-EM structure of human bradykinin receptor B2R bound to antagonist Win64338
Local refinement of the pre-ejectosome region within the bacteriophage RAN69 pre-ejectosome-portal complex
The consensus Cryo-EM structure of bacteriophage RAN69 pre-ejectosome-portal complex
The composite Cryo-EM structure of the tail region of bacteriophage RAN69
Cryo-EM structure of human bradykinin receptor B1R bound to antagonist ELN441958
The consensus Cryo-EM structure of the tail region of bacteriophage RAN69
Cryo-EM structure of human bradykinin receptor B1R bound to antagonist R715
Cryo-EM structure of the histone deacetylase complex Rpd3L in complex with di-nucleosome
Human claudin 18.2 in complex with the Fab fragment of Osemitamab (TST001)
Human claudin 18.2 (dimer form) in complex with the Fab fragment of Osemitamab (TST001)
Cryo-EM structure of icosahedrally averaged bacteriophage RAN69 capsid
Cellular environment of FIB-sectioned yeast cell overexpressing Brr6(I149D)
Aquifex aeolicus lumazine synthase 10-pentamer cage in complex with riboflavin synthase trimer
Aquifex aeolicus lumazine synthase 11-pentamer cage in complex with riboflavin synthase trimer
Aquifex aeolicus lumazine synthase 11-pentamer cage in complex with C5-symmetrized riboflavin synthase C-termini
Aquifex aeolicus lumazine synthase 12-pentamer cage in complex with I-symmetry-masked riboflavin synthase
Cryo-EM structure of human sodium pump W931R mutant in K+-occluded E2-Pi state
Cryo-EM structure of the human LENG8-PCID2-DSS1 complex bound to UAP56 and RRP1B
Cryo-EM structure of a human sodium pump wildtype in ouabain-bound E2P state
Cryo-EM structure of a human sodium pump W931R mutant in ouabain-bound E2P state
Cryo-EM structure of the human GANP-PCID2-DSS1 complex bound to UAP56
Cryo-EM structure of the C. elegans UBR4/KCMF1 complex (composite map)
Mammalian AP3 complex on tubular membranes (ARF1 centered Beta3-ARF1 dimer-Delta interface)
Mammalian AP3 complex on tubular membranes (ARF1 centered Beta3-ARF1 dimer-Beta3 interface)
CryoEM structure of transcribing RNA polymerase II elongation complex
Mammalian AP3 complex on tubular membranes (ARF1 centered Delta-ARF1 dimer-Delta3 interface)
Adenosine receptor A2a (A2AR)-beta-lactamase fusion bound to beta-lactamase inhibitory protein II (BLIPII) and ZM241385
Assembly intermediate of human mitochondrial ribosome small subunit in complex with PUS1, METTL15 and RBFA(IN conformation) (state M1)
Structure of the human chimera HCN112 hyperpolarization-activated cyclic nucleotide-gated ion channel in complex with cAMP.
Cryo-EM structure of hSA3, a mutated hyper-soluble human serum albumin designed for bacterial expression
Polysaccharide co-polymerase closed FepE 9 subunit complex C1 symmetry.
Polysaccharide co-polymerase FepE closed 9 subunit complex C9 symmetry
Cryo-ET of mitochondrial membrane in direct interaction with alpha-synuclein exhibiting membrane morphological distortion
Supplemental: irregularly shaped mitochondria interacting with alpha-synuclein
Supplemental: alpha-synuclein oligomers on the surface of a mitochondrial membrane
Cryo-EM structure of EV-D68 B3 VLP bound by neutralizing antibody 5H03
Cryo-EM structure of EV-D68 B3 VLP bound by neutralizing antibody 1E11
Structure of ADan amyloid filaments from synthesized ADan peptide
Structure of Type III ABri amyloid filaments extracted from human brain of Familial British Dementia patient
Structure of ABri amyloid filaments from synthesized ABri peptide
Structure of Type I ABri amyloid filaments extracted from human brain of Familial British Dementia patient
Structure of ADan amyloid filaments extracted from human brain of Familial Danish Dementia patient
Structure of Type II ABri amyloid filaments extracted from human brain of Familial British Dementia patient
CryoEM structure of the E. coli zinc ABC transporter ZnuB-ZnuC E146Q in complex with ATP
CryoEM structure of the E. coli zinc ABC transporter ZnuB-ZnuC in complex with AMP-PNP
CryoEM structure of the E. coli zinc ABC transporter ZnuB-ZnuC treated with EDTA
Localized reconstruction of the asymmetric unit of SINV/EEEV in complex with Fab EEEV-33 at arm 4 at pH 5.6.
Cryo-EM structure of the salivary protein complex Saglin-SGS4 from Anopheles gambiae
Localized reconstruction of the asymmetric unit of the low pH treated back neutralized SINV/EEEV in complex with Fab fragment of the antibody EEEV-179
Localized reconstruction of the asymmetric unit of SINV/EEEV at pH 5.6.
Localized reconstruction of the asymmetric unit of SINV/EEEV at 40C sample.
Localized reconstruction of the asymmetric unit of SINV/EEEV in complex with Fab EEEV-179 at 40C sample.
Chloroplast Glutamyl Peptidase S781R in closed-closed conformation
Cryo-EM structure of the core region of cIL-U1A-Fab1R-PGA1-sfFab quaternary complex at 2.9 A resolution
Cryo-EM structure of the open state of cIL RNA region at 4.3 A resolution
The composite map of cIL-U1A-Fab1R-PGA1-sfFab18 quaternary complex
Localized reconstruction of the asymmetric unit of the low pH treated back neutralized SINV/EEEV.
Composite map of six VRC35 Fabs and three MEDI8852 Fabs bound to influenza H3N2 Victoria 2011 hemagglutinin
Structure of an adenovirus hexon with Zwitterionic insertion in HVR5
Complex of B19V VP1u RBD and human transferrin receptor ectodomain
Cryo-EM structure of GPR119 in complex with partial agonist AS1268574 and Gs protein
Cryo-EM structure of the 48-nm repeat doublet microtubule from mouse sperm
The binding of a C-based single-domain antibody stabilizes spikes of SARS-CoV2 (JN.1) in all-RBD-up conformation
The binding of a C-based single-domain antibody stabilizes spikes of SARS-CoV2 (Delta) in all-RBD-up conformation
The binding of a C-based single-domain antibody stabilizes spikes of SARS-CoV2 (BA.5) in all-RBD-up conformation
The binding of a C-based single-domain antibody stabilizes spikes of SARS-CoV2 (BA.2) in all-RBD-up conformation
The binding of a C-based single-domain antibody stabilizes spikes of SARS-CoV2 (BA.1) in all-RBD-up conformation
Cryo-EM structure of the human KCNQ2/3 heteromer channel in the XEN1101-bound open state
Three RBD domains of the spike protein of SARS-CoV-2 JN.1 present two up and one down conformation
The local refine of 3D reconstruction of the complex formed by SARS-CoV2 BA.1 spike glycoprotein and a single-domain antibody
Three RBD domains of the spike protein of SARS-CoV-2 JN.1 present all down conformation.
Three RBD domains of the spike protein of SARS-CoV-2 JN.1 present one up and two down conformation
Structure of the apo state of human betaine/GABA transporter 1 in the inward-facing conformation
Structure of the apo state of human betaine/GABA transporter 1 in the occluded conformation
Structure of GABA-bound state of the human betaine/GABA transporter 1
Structure of ATPCA-bound state of the human betaine/GABA transporter 1
Structure of BPDBA-bound state of the human betaine/GABA transporter 1
Structure of betaine-bound state of the human betaine/GABA transporter 1
Cryo-EM structure of human MOR-Gi1 complex protein bound with DAMGO and BMS986187
Cryo-EM structure of the inner core of ArlA2 filament of Haloarcula marismortui
Visualization of PriA/PriB/DnaT complexes reveals mechanisms governing structure-specific assembly of the DNA replication restart primosome
Visualization of PriA/PriB/DnaT complexes reveals mechanisms governing structure-specific assembly of the DNA replication restart primosome
Human Excitatory Amino Acid Transporter 3 in 300 mM potassium and 0.1 mM Cmpd 3e in the outward-facing (OFS) state
Cryo-EM structure of HCoV-OC43-Lab Spike glycoprotein in complex with 9O-acetyl GD3 sialoglycan
Cryo-EM structure of HCoV-OC43-C2 Spike glycoprotein (local refined D1 domain)
Cryo-EM structure of HCoV-OC43-C2 Spike glycoprotein in complex with 9O-acetyl GD3 sialoglycan (Local refined D1 domain)
Chlamydia muridarum major outer membrane protein bound to Mus musculus MAB-18B Fab
Cryo-EM structure of HCoV-OC43-Lab Spike glycoprotein in complex with 9O-acetyl GD3 sialoglycan (D1 domain local refine)
Focused refinement cryo-EM map of the A/B/C subunits of the T=3 lake sinai virus 1 (delta N-terminal 48 residues) virus-like particle at pH 6.5
Cryo-EM structure of human ABCD3 in inward-facing conformation in the presence of phytanoyl-CoA
Cryo-EM structure of ATP bound state human ABCD3 in outward-facing conformation
Cryo-EM structure of CHS bound state human ABCD3 in inward-facing conformation
Cryo-EM structure of C20:5-CoA bound state human ABCD3 in inward-facing conformation
Cryo-EM structure of ATP bound state human ABCD3 in inward-facing conformation
CryoEM structure of transcribing RNA polymerase II elongation complex in post-catalysis state
Focused refinement of the MGRN1 ubiquitin ligase in complex with helix-stabilized MEGF8, MOSMO and nanobody 270
Focused refinement of the MEGF8 and MOSMO extracellular domains with nanobody 992
Focused refinement of the MGRN1 ubiquitin ligase in complex with MEGF8, MOSMO and nanobody 270
Structure of the MEGF8-MOSMO complex with nanobody 270 (Focused refinement)
Structure of the MMM ubiquitin ligase complex with nanobody 992 (Consensus map)
Structure of the MMM ubiquitin ligase complex with nanobody 270 (Consensus map)
Focused refinement of the MGRN1 ubiquitin ligase in complex with MEGF8, MOSMO and nanobody 992
Cryo-EM structure of the helix-stabilized MMM ubiquitin ligase complex with nanobody 270 (Composite map)
Structure of the helix-stabilized MMM ubiquitin ligase complex with nanobody 270 (Consensus map)
Cryo-EM structure of the MMM ubiquitin ligase complex with nanobody 270 (Composite map)
Cryo-EM structure of the MMM ubiquitin ligase complex with nanobody 992 (Composite map)
Cryo-EM structure of the binary MEGF8-MOSMO complex with nanobody 270
Human Signal Peptidase in complex with artificial Signal Peptide L11
Focused refinement of the helix-stabilized MEGF8-MOSMO complex with nanobody 270
EMCV IRES captured on mammalian 40S ribosome with initiator tRNA and eIF2
Cryo-EM structure of KCa2.2/calmodulin channel in complex with SKA111.
Cryo-EM structure of P. urativorans 70S ribosome after 24h acute stress - State 2: E-tRNA/P-tRNA/A-tRNA
Cryo-EM structure of P. urativorans 70S ribosome after 2h acute stress - State 2: E-tRNA/P-tRNA/A-tRNA
Cryo-EM structure of P. urativorans 70S ribosome after 2h acute stress - State 4: E-tRNA/RaiA/Balon




