EMD-53313

Single-particle
2.65 Å
EMD-53313
3D View Gallery
Deposition: 02/04/2025
Map released: 27/05/2026
Last modified: 17/06/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-53313

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9qqs summary report (pdf.gz) Map-9qqs FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Structure of the MEGF8-MOSMO complex with nanobody 270 (Focused refinement)

EMD-53313

Single-particle
2.65 Å
EMD-53313
3D View Gallery
Deposition: 02/04/2025
Map released: 27/05/2026
Last modified: 17/06/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Lama glama
Sample: Focused refinement of the MEGF8-MOSMO binary complex bound to nanobody 270
Fitted models: 9qqs

Deposition Authors: Williams C, Carrique L, Pardon E, Nocka LM, Hedger G, Pusapati GV, Parashara P, Latorraca NR, Sarkar P, Lartey D, Gao L, Milenkovic L, Chalk R, Steyaert J, Bazan F, Rouse SL, Marqusee S, Kong JH, Rohatgi R, Siebold C
Design principles of a membrane-spanning ubiquitin ligase.
Williams C, Nocka LM, Hedger G, Parashara P, Pardon E, Latorraca NR, Pusapati GV, Sarkar P, Lartey D, Gao L, Milenkovic L, Chalk R, Steyaert J, Marqusee S, Carrique L, Bazan JF, Rouse SL, Kong JH, Siebold C, Rohatgi R
(2026) Mol Cell , 86 , 2207
PUBMED: 42190653
DOI: doi:10.1016/j.molcel.2026.05.001
ISSN: 1097-2765
ASTM: MOCEFL
Grant Support: