EMD-75049

Single-particle
3.24 Å
EMD-75049
3D View Gallery
Deposition: 09/01/2026
Map released: 27/05/2026
Last modified: 27/05/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-75049
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
EMICSS annotations (xml)

Human Excitatory Amino Acid Transporter 3 in 300 mM potassium and 0.1 mM Cmpd 3e in the outward-facing (OFS) state

EMD-75049

Single-particle
3.24 Å
EMD-75049
3D View Gallery
Deposition: 09/01/2026
Map released: 27/05/2026
Last modified: 27/05/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: human excitatory amino acid transporter 3

Deposition Authors: Earsley A , Qiu B , Boudker O
Structure-guided optimization of SLC1A1/EAAT3-selective inhibitors targeting renal cancer metabolism.
Koochaki P, Qiu B , Coker JA, Earsley A , Wang NS, Romigh T, Goins CM, Salem C, Mi D, Days E, Bauer JA, Stauffer SR, Boudker O , Chakraborty AA
(2026) EMBO J
PUBMED: 42020573
DOI: doi:10.1038/s44318-026-00776-2
ISSN: 1460-2075
ASTM: EMJODG
Grant Support: