EMD-72985
AM12-351 Fab in complex with HIV-1 Env 5MUT-3fill SOSIP
EMD-72985
Single-particle4.3 Å
Deposition: 01/10/2025Map released: 27/05/2026
Last modified: 08/07/2026
Sample Organism:
Human immunodeficiency virus 1
Sample: HIV-1 Envelope protein
Fitted models: 9yib
Deposition Authors: Gristick HB
,
Gavor E ,
Bjorkman PJ
Sample: HIV-1 Envelope protein
Fitted models: 9yib
Deposition Authors: Gristick HB
,
Gavor E ,
Bjorkman PJ
Induction of broadly neutralizing HIV antibodies by a two-step mechanism informs vaccine design.
Skelly AN ,
Gristick HB ,
Li H ,
Gavor E ,
Connell AJ ,
Kreider EF ,
Marchitto L ,
Hogarty MP ,
Newby ML ,
Allen JD ,
Liu W ,
West Jr AP ,
Ayyanathan K ,
Campion MS,
Winters K,
Gordon CG,
Osbaldeston RA ,
Akeley MJ ,
Lewis E ,
Li Y ,
Singh A ,
Cruickshank K ,
Park Y ,
Zhao C,
Li X ,
Amereh K ,
Van Itallie E ,
Carey JW ,
Albertus A ,
DeLaitsch AT ,
Keeffe JR ,
Lituchy MG,
Walsh AA,
Morris DJ ,
Habib R ,
Bibollet-Ruche F ,
Mishra N ,
Avillion G ,
Koranda NS,
Plante SJ ,
Martella CL ,
Lora J ,
Wang EJD ,
Lewis MG ,
Martin MA ,
Nussenzweig MC ,
Seaman MS ,
Irvine DJ ,
Wiehe KJ,
Haynes BF ,
Wagh K ,
Korber B ,
Andrabi R ,
Crispin M ,
Weissman D ,
Bjorkman PJ ,
Hahn BH,
Shaw GM
(2026) Science , 392 , eaec6396 - eaec6396
,
Gristick HB ,
Li H ,
Gavor E ,
Connell AJ ,
Kreider EF ,
Marchitto L ,
Hogarty MP ,
Newby ML ,
Allen JD ,
Liu W ,
West Jr AP ,
Ayyanathan K ,
Campion MS,
Winters K,
Gordon CG,
Osbaldeston RA ,
Akeley MJ ,
Lewis E ,
Li Y ,
Singh A ,
Cruickshank K ,
Park Y ,
Zhao C,
Li X ,
Amereh K ,
Van Itallie E ,
Carey JW ,
Albertus A ,
DeLaitsch AT ,
Keeffe JR ,
Lituchy MG,
Walsh AA,
Morris DJ ,
Habib R ,
Bibollet-Ruche F ,
Mishra N ,
Avillion G ,
Koranda NS,
Plante SJ ,
Martella CL ,
Lora J ,
Wang EJD ,
Lewis MG ,
Martin MA ,
Nussenzweig MC ,
Seaman MS ,
Irvine DJ ,
Wiehe KJ,
Haynes BF ,
Wagh K ,
Korber B ,
Andrabi R ,
Crispin M ,
Weissman D ,
Bjorkman PJ ,
Hahn BH,
Shaw GM
(2026) Science , 392 , eaec6396 - eaec6396
Grant Support: