EMD-64563

Single-particle
3.1 Å
EMD-64563
3D View Gallery
Deposition: 12/05/2025
Map released: 27/05/2026
Last modified: 27/05/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-64563

Archive Files (Depositor)

Primary 3D volume (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9uwq summary report (pdf.gz) Map-9uwq FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

A combined Cryo_EM structure of Cagrilintide-AMY1R-Gs complex

EMD-64563

Single-particle
3.1 Å
EMD-64563
3D View Gallery
Deposition: 12/05/2025
Map released: 27/05/2026
Last modified: 27/05/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: A combined Cryo_EM structure of Cagrilintide-AMY1R-Gs complex
Fitted models: 9uwq

Deposition Authors: Yuan Q, Zhao L, Gu Y
Structural and mechanistic insights into dual activation of cagrilintide in amylin and calcitonin receptors.
Gu YM, Yuan QN, Li X, He Q, Xu HE, Zhao LH
(2026) Acta Pharmacol.Sin. , 47 , 162 - 172
PUBMED: 40847076
DOI: doi:10.1038/s41401-025-01635-2
ISSN: 1745-7254